Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging
Andersson, Daniel C., Betzenhauser, Matthew J., Reiken, Steven, Meli, Albano C., Umanskaya, Alisa, Xie, Wenjun, Shiomi, Takayuki, Zalk, Ran +2 more·2011·Cell Metabolism
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- Prolonged force depression after mechanically demanding contractions is largely independent of Ca 2+ and reactive oxygen speciesSigitas Kamandulis, Felipe de Souza Leite, Andrés Hernández, Abram Katz, Marius Brazaitis, Joseph D. Bruton, Tomas Venckūnas, Nerijus Masiulis, Dalia Mickevičienė, Nerijus Eimantas et al. · 2017 · The FASEB Journal
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- Mechanisms Modulating Skeletal Muscle PhenotypeBert Blaauw, Stefano Schiaffino, Carlo Reggiani · 2013 · Comprehensive physiology
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- Diet quality and osteosarcopenic obesity in community-dwelling adults 50 years and olderKim, Jinhee, Lee, Yunhwan, Kye, Seunghee, Chung, Yoon-Sok, Kim, Jae-Hyun, Chon, Doukyoung, Lee, Kyung Eun · 2017 · Maturitas
- Enhanced dihydropyridine receptor calcium channel activity restores muscle strength in JP45/CASQ1 double knockout miceBarbara Mosca, Osvaldo Delbono, Marı́a Laura Messi, Leda Bergamelli, Zhongmin Wang, Mirko Vukcevic, Rubén López, Susan Treves, Miyuki Nishi, Hiroshi Takeshima et al. · 2013 · Nature Communications
- Coupling of excitation to Ca2+release is modulated by dysferlinValeriy I. Lukyanenko, Joaquin M. Muriel, Robert J. Bloch · 2017 · The Journal of Physiology
- Preclinical model systems of ryanodine receptor 1-related myopathies and malignant hyperthermia: a comprehensive scoping review of works published 1990–2019Tokunbor A. Lawal, Emily S. Wires, Nancy L. Terry, James J. Dowling, Joshua J. Todd · 2020 · Orphanet Journal of Rare Diseases
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- Cellular crosstalk in cardioprotection: Where and when do reactive oxygen species play a role?Tânia Martins‐Marques, Antonio Rodríguez‐Sinovas, Henrique Girão · 2021 · Free Radical Biology and Medicine
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- Weakness, SR function and stress in gastrocnemius muscles of aged male ratsDavid W. Russ, Allison M. Wills, Iva M. Boyd, Jodi Krause · 2013 · Experimental Gerontology
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- "Sr stress" in mixed hindlimb muscles of aging Male ratsRuss, David W., Krause, Jodi, Wills, Allison, Arreguin, Raymond · 2012 · Biogerontology
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- A TGF-β pathway associated with cancer cachexiaDenis C. Guttridge D · 2015 · Nature Medicine
- Impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca2+ handling across the adult lifespan in menMarina Cefis, Vincent Marcangeli, Rami Hammad, Jordan Granet, Jean‐Philippe Leduc‐Gaudet, Pierrette Gaudreau, Caroline Trumpff, Qiuhan Huang, Martin A. Picard, Mylène Aubertin‐Leheudre et al. · 2025 · Cell Reports Medicine
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- Causes and consequences of age-related changes at the neuromuscular junctionDaniel J. Ham, Markus A. Rüegg · 2018 · Current Opinion in Physiology
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