The Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, and Metabolic and Disease Implications

Carrico, Chris, Meyer, Jesse G., He, Wenjuan, Gibson, Brad W., Verdin, Eric·2018·Cell Metabolism

Cited by (343)

Items 201–300 of 343

  1. SIRT5 inhibition impairs mitochondrial metabolism and enhances venetoclax-induced elimination of acute myeloid leukemia cells
    Moran Wang, Ruiqi Zhu, Donald Small, Lan Lin, Li Li, Shengling Ma, Linghui Xia, Shanshan Luo, Wenjuan He, Jianming Yu et al. · 2025 · Leukemia
  2. Mitochondrial malfunction-initiated Leydig cell premature senescence partially participates in 1-nitropyrene-evoked downregulation of steroidogenic synthases in testes
    Jian Li, Xin Dong, Lan Gao, Weiwei Zhang, Fang-Jie Zhong, Suya Liu, Yichao Huang, Yan Wang, Wei Wei, DongDong Xie · 2024 · Free Radical Biology and Medicine
  3. In‐depth analysis of the Sirtuin 5‐regulated mouse brain malonylome and succinylome using library‐free data‐independent acquisitions
    Joanna Bons, Jacob Rose, Ran Zhang, Jordan B. Burton, Christopher Carrico, Eric M. Verdin, Birgit Schilling · 2022 · PROTEOMICS
  4. Proteomics of Long‐Lived Mammals
    Gregory Tombline, Jonathan Gigas, Nicholas Macoretta, Max Zacher, Stephan Emmrich, Yang Zhao, Andrei Seluanov, Vera A. Gorbunova · 2019 · PROTEOMICS
  5. Mitochondrial protein phosphorylation in yeast revisited
    Ján Frankovský, Veronika Vozáriková, Jozef Nosek, Ľubomír Tomáška · 2021 · Mitochondrion
  6. Epigenetic Regulation by Dietary Restriction: Part II.
    Gavin Yong-Quan Ng, David Yang‐Wei Fann, Dong‐Gyu Jo, Christopher Graeme Sobey, Thiruma Valavan Arumugam · 2019 · PubMed
  7. Deacetylation of GLUD1 maintains the survival of lung adenocarcinoma cells under glucose starvation by inhibiting autophagic cell death
    Qifan Hu, Longhua Sun, Zhujun Cheng, Lei Wang, Xiaorui Wan, Jing Xu, Junyao Cheng, Zuorui Wang, Yi Yuan, Keru Wang et al. · 2024 · Cell Insight
  8. Mitochondrial Sirt3 serves as a biomarker for sepsis diagnosis and mortality prediction
    Jingjing Liu, Gaosheng Zhou, Rongping Chen, Zewen Tong, Hongmin Zhang, Xiaoting Wang, Dawei Liu · 2022 · Scientific Reports
  9. A high-fat diet increases hepatic mitochondrial turnover through restricted acetylation in a NAFLD mouse model
    Mirjavid Aghayev, Andrea Arias-Alvarado, Sergei Ilchenko, Josephine Lepp, Iain Scott, Yeong‐Renn Chen, Guofang Zhang, Tsung‐Heng Tsai, Takhar Kasumov · 2023 · American Journal of Physiology-Endocrinology and Metabolism
  10. In-silico screening of bioactive phytopeptides for novel anti-ageing therapeutics
    Rahagir Salekeen, Asif Ahmed, Md. Emdadul Islam, Md Morsaline Billah, Hafizur Rahman, Kazi Mohammed Didarul Islam · 2020 · Journal of Biomolecular Structure and Dynamics
  11. SIRT4 regulates rat dental papilla cell differentiation by promoting mitochondrial functions
    Haoling Chen, Jun Kang, Fuping Zhang, Tong Yan, Wenguo Fan, Hongwen He, Fang Ping Huang · 2021 · The International Journal of Biochemistry & Cell Biology
  12. A Comprehensive Proteome and Acetyl-Proteome Atlas Reveals Molecular Mechanisms Adapting to the Physiological Changes From Pre-laying to Peak-Laying Stage in Liver of Hens (Gallus gallus)
    Zhang Wang, Dandan Wang, Keren Jiang, Yulong Guo, Zhuanjian Li, Ruirui Jiang, Ruili Han, Guoxi Li, Yadong Tian, Hong Li et al. · 2021 · Frontiers in Veterinary Science
  13. The Multi-Faceted Nature of Renalase for Mitochondrial Dysfunction Improvement in Cardiac Disease
    Dijana R. Stojanović, Miodrag Stojanović, Jelena Milenković, Aleksandra Veličkov, Aleksandra Ignjatović, Maja Milojković · 2023 · Cells
  14. The mitochondrial multi-omic response to exercise training across tissues
    David Amar, Nicole R. Gay, David Jimenez‐Morales, Pierre M. Jean Beltran, Megan E. Ramaker, Archana Natarajan Raja, Bingqing Zhao, Yifei Sun, Shruti Marwaha, David A. Gaul et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  15. SIRT3 regulates PFKFB3-mediated glycolysis to attenuate cisplatin-induced ototoxicity both in vivo and in vitro
    Wei Tang, Shimin Zong, Peiyu Du, Xuan Yu, Ting Li, Bo Liu, Yu Zhong, Wenyang Lei, Wenting Yu, Hongjun Xiao · 2025 · Archives of Toxicology
  16. Endothelial SIRT3 deficiency predisposes brown adipose tissue to whitening in diet-induced obesity
    Qing Zhou, Zongshi Lu, Bowen Wang, Yuyan Wang, Li Li, Mei You, Lijuan Wang, Tingbing Cao, Dan Tong, Jie Xiang et al. · 2025 · International Journal of Biological Sciences
  17. Acetylation of the Mitochondrial Chaperone GRP75 Governs ER‐Mitochondrial Calcium Homeostasis and Hepatocyte Insulin Resistance
    Danni Wang, Jiaqi Zhang, Xinyu Yang, Qiqi Zhang, Xiuya Hu, Xin Lu, Hao Li, Xue Li Bai, Kai Zhang, Michael N. Sack et al. · 2025 · Advanced Science
  18. Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis in the Regulation of Metabolism, Aging, and Neurodegeneration
    Stephanie Maxine Ross · 2021 · Holistic Nursing Practice
  19. Aberrant SENP1-SUMO-Sirt3 Signaling Causes the Disturbances of Mitochondrial Deacetylation and Oxidative Phosphorylation in Prion-Infected Animal and Cell Models
    Dongdong Chen, Qi Shi, Xin Zhe Liu, Dong-Lin Liang, Yue-Zhang Wu, Qin Fan, Kang Xiao, Cao Chen, Xiao‐Ping Dong · 2023 · ACS Chemical Neuroscience
  20. 4′-O-methylbavachalcone alleviates ischemic stroke injury by inhibiting parthanatos and promoting SIRT3
    Hong-qing Chen, Q G Zhang, Xin-yuan Zhang, Xiang-bing Zeng, Jin‐Wen Xu, Shuang Ling · 2024 · European Journal of Pharmacology
  21. Recent advances in MDS mutation landscape: Splicing and signalling
    Matilde Y. Follo, Andrea Pellagatti, Stefano Ratti, Giulia Ramazzotti, Irene Faenza, Roberta Fiume, Sara Mongiorgi, Pann‐Ghill Suh, James Andrew McCubrey, Lucia Manzoli et al. · 2019 · Advances in Biological Regulation
  22. LncRNA DLEU2 regulates sirtuins and mitochondrial respiratory chain complex IV: a novel pathway in obesity and offspring’s health
    Jian Zhang, Matthew Kay, Min Hi Park, Sunitha Meruvu, Catherine A. Powell, Mahua Choudhury · 2022 · International Journal of Obesity
  23. Six mitophagy-related hub genes as peripheral blood biomarkers of Alzheimer’s disease and their immune cell infiltration correlation
    Kun Zhao, Yinyan Wu, Dongliang Zhao, Hui Zhang, Jianyang Lin, Yuanwei Wang · 2023 · Frontiers in Neuroscience
  24. Alterations in mitochondrial structure and function in response to environmental temperature changes in Apostichopus japonicus
    Lixin Lu, Yang Yu, Guojun Shi, Xiaohua He, Xiaohui Xu, Yanwei Feng, Weijun Wang, Zan Li, Jianmin Yang, Bin Li et al. · 2023 · Marine Environmental Research
  25. Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization
    Xueshu Xie, Samah Shah, Anja N. Holtz, Jacob Rose, Nathan Basisty, Birgit Schilling · 2020 · Journal of Visualized Experiments
  26. Regulation of apoptosis, ferroptosis, and pyroptosis mediated by acetylation
    Weijie Lu, Yaoting Deng, Mengyang Liu, Yujie Hu, Kang Yang, Bowen Wang, Yanling Li, gang wang, Li Ma, JIA LIU et al. · 2026 · Cell Death Discovery
  27. Sirtuins—Novel Regulators of Epigenetic Alterations in Airway Inflammation
    Shunyu Wu, Huanhai Liu · 2022 · Frontiers in Genetics
  28. Post-Translational Modifications by Lipid Metabolites during the DNA Damage Response and Their Role in Cancer
    Guang-Rong Zhu, Xiangyang Zheng, Zhifeng Wang, Xingzhi Xu · 2022 · Biomolecules
  29. Low-level Nd:YAG laser inhibiting inflammation and oxidative stress in human gingival fibroblasts via AMPK/SIRT3 axis
    Haizheng Zhang, Chenyi Zhang, Lai Pan, Yifan Chen, Zirui Bian, Yuxuan Yang, Ting Ke, Weilian Sun, Lili Chen, Jingyi Tan · 2024 · Journal of Photochemistry and Photobiology B Biology
  30. Energy metabolism and redox balance: How phytochemicals influence heart failure treatment
    Cong Chen, Jie Wang, Xueying Zhu, Jun Hu, Chao Liu, Lanchun Liu · 2024 · Biomedicine & Pharmacotherapy
  31. Succinylation regulates boar sperm linear motility via reprogramming glucose metabolism
    Qi Wang, Shanpeng Wang, Wenxian Zeng, Adedeji O. Adetunji, Lingjiang Min, Masayuki Shimada, Zhendong Zhu · 2025 · Communications Biology
  32. Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function
    Dharendra Thapa, Janet R. Manning, Bellina A.S. Mushala, Michael Wayne Stoner, Manling Zhang, Iain Scott · 2020 · Current Research in Physiology
  33. Non-oncogene Addiction to SIRT5 in Acute Myeloid Leukemia
    Meng Li, Ari M. Melnick · 2021 · Blood Cancer Discovery
  34. Protein succinylation mechanisms and potential targeted therapies in urinary disease
    Yuanquan Lou, Caitao Dong, Qinhong Jiang, Ziqi He, Sixing Yang · 2025 · Cellular Signalling
  35. Targeted Redox Regulation α-Ketoglutarate Dehydrogenase Complex for the Treatment of Human Diseases
    Ryan J. Mailloux · 2025 · Cells
  36. A bicyclic pentapeptide-based highly potent and selective pan-SIRT1/2/3 inhibitor harboring Nε-thioacetyl-lysine
    Renwu Li, Lingling Yan, Xun Sun, Weiping Zheng · 2020 · Bioorganic & Medicinal Chemistry
  37. Lysine acetylome profiling in mouse hippocampus and its alterations upon FMRP deficiency linked to abnormal energy metabolism
    Yue-Ying Wu, Cui Yang, Hua-Juan Yan, Ping Lu, Li Zhang, Weng-Cai Feng, Yue‐Sheng Long · 2022 · Journal of Proteomics
  38. Sirt3 increases CNPase enzymatic activity through deacetylation and facilitating substrate accessibility
    Dongfang Wang, Keai Sinn Tan, Xabier Arias‐Moreno, Wen Tan, Guohua Cheng · 2021 · Biochemical and Biophysical Research Communications
  39. Kinetic characterization of inhibitors of histone deacetylases (HDACs) and sirtuins
    Carlos Moreno–Yruela, Andreas S. Madsen, Christian Adam Olsen · 2019 · Research Square
  40. The Great Deceiver: miR-2392’s Hidden Role in Driving SARS-CoV-2 Infection
    Jackie McDonald, Francisco J. Enguita, Deanne M. Taylor, Robert J. Griffin, Waldemar Priebe, Mark R. Emmett, Mohammad M. Sajadi, Anthony D. Harris, Jean Clement, Joseph M. Dybas et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  41. The Crucial Role of NAD+ in Mitochondrial Metabolic Regulation
    Kumudesh Mishra, Or Kakhlon · 2025 · Biocell
  42. Design, synthesis and biological evaluation of 2,4,6- trisubstituted triazine derivatives as new nonpeptide small-molecule SIRT5 inhibitors
    Lijiao Wang, Lei Hu, Jianlin Deng, Suyan Hou, Luohe Mou, Pengcheng Lei, Xi Chen, Jiayu Liu, Yingying Jiang, Rui Xiong et al. · 2023 · Bioorganic & Medicinal Chemistry
  43. Natural compounds targeting cellular redox homeostasis in malignancies
    Xue Li, Dan Li · 2023 · Cellular and Molecular Biology
  44. Timing of dietary effects on the epigenome and their potential protective effects against toxins
    Lynnea A. Nicholls, Kendall A. Zeile, London D. Scotto, Rebecca Jean Ryznar · 2025 · Epigenetics
  45. Preventative effect of TSPO ligands on mixed antibody-mediated rejection through a Mitochondria-mediated metabolic disorder
    Yannan Zhang, Jiannan He, Zhe Yang, Haofeng Zheng, Haoxiang Deng, Zihuan Luo, Qipeng Sun, Qiquan Sun · 2023 · Journal of Translational Medicine
  46. Modulation of the Activity of Succinate Dehydrogenase by Acetylation with Chemicals, Drugs, and Microbial Metabolites
    Nadezhda I. Fedotcheva, Marie N. Kondrashova, E. G. Litvinova, Marina V. Zakharchenko, Natalia V. Khunderyakova, Beloborodova Nv · 2018 · BIOPHYSICS
  47. Hepatic ketogenesis regulates lipid homeostasis via ACSL1-mediated fatty acid partitioning
    Sadeesh Kumar Ramakrishnan, Raja Gopal Reddy Mooli, Yerin Han, Ericka J. Fiorenza, Suchita Kumar, Fiona M. Bello, Anoop R. Nallanagulagari, Shreya Karra, Lihong Teng, Michael J. Jurczak · 2023 · Research Square
  48. Hepatic Ketogenesis Regulates Lipid Homeostasis via ACSL1-mediated Fatty Acid Partitioning
    Raja Gopal Reddy Mooli, Yerin Han, Ericka J. Fiorenza, Karthik Balakrishnan, Jitendra Singh Kanshana, Suchita Kumar, Fiona M. Bello, Anoop R. Nallanagulagari, Shreya Karra, Junyan Tao et al. · 2025 · Cellular and Molecular Gastroenterology and Hepatology
  49. TRAP1 inhibits KANSL3 acetylation to alleviate mitochondrial dysfunction by promoting mitophagy in cardiomyocytes under diabetic conditions
    Xiaoyu Zhang, Shiyao Cheng, Wenxin Li, Xintian Xu, Xiaojing Huang, Zhichong Chen, Qinglang Li, Wanjing Huang, Lingxiao Zhang, Mao Ouyang · 2025 · Cell Communication and Signaling
  50. Alpha-ketoglutarate dehydrogenase: more than just a TCA cycle enzyme
    Ryan J. Mailloux · 2026 · Free Radical Biology and Medicine
  51. The Role of the Sirt1/Foxo3a Pathway in Mitigating Myocardial Ischemia–Reperfusion Injury by Dexmedetomidine
    Hanlin Ding, Danyong Liu, Jianfeng He, Dongcheng Zhou, Chan Wang, Changming Yang, Zhongyuan Xia · 2025 · Chemical Biology & Drug Design
  52. Glutamate Dehydrogenase as a Promising Target for Hyperinsulinism Hyperammonemia Syndrome Therapy
    Yunfei Bian, Wei Hou, Xinrou Chen, Jinzhang Fang, Ning Xu, Benfang Helen Ruan · 2021 · Current Medicinal Chemistry
  53. Proteomics profiling for the global and acetylated proteins of papillary thyroid cancers
    Wei Wei, Yue-Zhang Wu, Dongdong Chen, Yuntao Song, Guohui Xu, Qi Wu Shi, Xiao‐Ping Dong · 2023 · Proteome Science
  54. SIRT5 Regulates Lipid Deposition in Goat Preadipocytes via PI3K-Akt and MAPK Signaling Pathways
    Haiyang Li, Wenli Yao, Changheng Yang, Wenyang Zhang, Yong Wang, Yaqiu Lin, Zhanyu Du, Changhui Zhang, Lian Huang, Ming Zhang et al. · 2025 · Animals
  55. New role of obscure acylation modifications in cardiovascular diseases: what's beyond?
    Zhongyi Zhang, Wei Hu, Qian Ding, Yi Zhun Zhu · 2025 · Life Sciences
  56. Mechanism-driven multitarget therapeutics for diabetic peripheral neuropathy
    Shiyu Kong, Guanglei Nan, Yueyang Wang, Mingyan Du, Yuanfang Kong, Lifeng Zhu, Xu Shen, Xiaofei Li, Chunhong Dong · 2025 · Neuroscience
  57. New insight into molecular mechanisms of different polyphenols affecting Sirtuin 3 deacetylation activity
    Yulong Wei, Yiman Zhang, Ziyuan Wang, Zihui Yang, Zongwei Wang, Yiming Hao, Genying Li, Fei Gao, Gaoqi Ye, Jing Wang et al. · 2024 · International Journal of Biological Macromolecules
  58. Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization
    Xueshu Xie, Samah Shah, Anja N. Holtz, Jacob Rose, Nathan Basisty, Birgit Schilling · 2020 · Journal of Visualized Experiments
  59. The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function
    João Soeiro Teodoro, João A. Amorim, Ivo F. Machado, Ana Catarina Castela, Clemens Steegborn, David A. Sinclair, Anabela Pinto Rolo, Carlos M. Palmeira · 2020 · International Journal of Molecular Sciences
  60. Sea buckthorn flavonoids and their derivatives: potential natural compounds for the treatment of diabetic cardiomyopathy
    Quan Zhang, Jiahong Zhang, Yujie Ouyang, Hongyan Liu, Chunguang Xie, Xiaoxu Fu · 2025 · Frontiers in Pharmacology
  61. SERPINE1 drives ferroptosis in acute respiratory distress syndrome by disrupting mitochondrial NAD+ homeostasis and suppressing Sirt3 activity
    Nan Gao, Wei-Jian Zhang, Yixin Qian, Song Yang, Zheng-Nan Zhang, Hao-tian Lu, Guo-Qiang Zhang · 2026 · Redox Biology
  62. SIRT7 promotes dental pulp stem cells replicative senescence through desuccinylation of ROCK1
    Rui Zhang, Jie Chen, Yuanyuan Chen, Yangyang Li · 2024 · Tissue and Cell
  63. The roles and mechanisms of CDGSH iron-sulfur domain 1 in kainic acid-induced mitochondrial iron overload, dysfunction and neuronal damage
    Jing Wang, Shuo Li, Haidong Xu, Jie Xue, Xiaorui Wan, Weilong Wu, Jiani Huang, Huiling Zhang, Zheng‐Hong Qin, Yán Wāng · 2025 · Biomedicine & Pharmacotherapy
  64. Preparation of Affinity Purified Antibodies against ε-Glutaryl-Lysine Residues in Proteins for Investigation of Glutarylated Proteins in Animal Tissues
    Artem V. Artiukhov, Ekaterina F. Kolesanova, Alexandra I. Boyko, Anastasiya A. Chashnikova, Sergei N. Gnedoy, Thilo Kaehne, Daria A. Ivanova, Alyona V. Kolesnichenko, Vasily A. Aleshin, Victoria I. Bunik · 2021 · Biomolecules
  65. Mitochondrial lysine acylation and cardiometabolic stress: truth or consequence?
    Deborah M. Muoio, Ashley S. Williams, Paul A. Grimsrud · 2022 · Current Opinion in Physiology
  66. GBDT_KgluSite: An improved computational prediction model for lysine glutarylation sites based on feature fusion and GBDT classifier
    Xin Liu, Bao Ting Zhu, Xia-Wei Dai, Zhi-Ao Xu, Rui Li, Yuting Qian, Yaping Lu, Wenqing Zhang, Yong U. Liu, Junnian Zheng · 2023 · BMC Genomics
  67. Identification of phytoestrogens as sirtuin inhibitor against breast cancer: Multitargeted approach
    Kojja Venkateswarlu, Vanitha Rudraram, Kancharla Bhanukiran, Hemalatha Siva, Anjana Devi Tangutur, Prasanta Kumar Nayak · 2024 · Computational Biology and Chemistry
  68. A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function
    Rachid Boutoual, Hyunsun Jo, Indra Heckenbach, Ritesh Tiwari, Herbert G. Kasler, Chad A. Lerner, Samah Shah, Birgit Schilling, Vincenzo Calvanese, Matthew J. Rardin et al. · 2022 · Scientific Reports
  69. Sirtuins, healthspan, and longevity in mammals
    Surinder Kumar, William Giblin, David B. Lombard · 2021 · Elsevier eBooks
  70. Sirt5 affects the metabolic remodeling of eosinophils by negatively regulating the level of succinylation modification of Pkm2 in eosinophilic chronic rhinosinusitis
    Shun‐Yu Wu, Bo‐Yu Cai, Zhi‐Wen Cao, Tianyu Wang, Caiquan Liang, Enhong Xu, Hu Peng, Jianchun‐Liao, Huanhai Liu · 2024 · World Journal of Otorhinolaryngology - Head and Neck Surgery
  71. Research progress on sirtuin family genes in colorectal cancer
    Tong Liu, Tianhua Wu, Lijun Luo, Wei Li, Minglin Zhang · 2025 · Frontiers in Oncology
  72. Urinary acetylated protein as a biomarker of lupus nephritis: a prospective cohort study
    Yeo‐Jin Lee, Eun‐Ju Lee, Kyunggon Kim, Minji Kim, Ji Young Yu, M.-S. Kim, Soo Min Ahn, Seok-Chan Hong, Chang‐Keun Lee, Bin Yoo et al. · 2025 · Arthritis Research & Therapy
  73. Destabilization of cardiac myosin acetylation and sequestration with type 2 diabetes mellitus
    Mahault Mathilde Degezelle, Chahida Chaami, Christopher T. A. Lewis, Chengxin Zhang, Anthony L. Hessel, Peter P. Rainer, Jonathan A. Kirk, Mathis K. Stokke, Robert A. E. Seaborne, Julien Ochala · 2026 · Cardiovascular Diabetology
  74. Gene Therapy for Heart Failure: Impact on Mitochondrial Dysfunction
    Mikhail Lvovich Blagonravov, Anastasia P. Sklifasovskaya, R. M. Karpov, Vera S. Ovechkina, S. K. Andrianova, Sergey P. Syatkin, Vsevolod Vadimovich Belousov, Andrey A. Mozhaev · 2026 · Biomedicines
  75. Novel high-resolution ion mobility mass spectrometry for site-specific quantification of the sirtuin-5 regulated kidney succinylome
    Birgit Schilling, Leonard C. Rorrer, Lauren Royer, Anne C. Silva Barbosa, Katherine E. Pfister, Eric S. Goetzman, Sunder Sims‐Lucas, Daniel DeBord, Joanna Bons · 2026 · Journal of Proteomics
  76. Chondrocyte Senescence in Osteoarthritis: Potential Targets and Pharmacological Interventions
    Dunyong Y. Tan, Jiawei Guo, Tianyu Wang, Siyao Yang, Jianquan Liu, Daping Wang, Wencui Li · 2026 · Cartilage
  77. Molecular mechanisms underlying Parkinson’s disease and role of phytochemicals, α-synuclein, sirtuins, and incretin mimetics in potential therapy
    Sanjida Shahid Juthi, Prawej Ansari, Md Ferdos Ahmed, Joyeeta Tahseen Khan, Véronique Seidel, Sandeep Kumar, Reena Kumari, Aine M. McKillop, Yasser H.A. Abdel‐Wahab, Peter R. Flatt · 2026 · Frontiers in Pharmacology
  78. A novel histone acetylation-associated gene signature with prognostic value in Ewing sarcoma
    Anshun Wu, Fayin Liu, Lei Zhou, Runyi Jiang, Shangjiang Yu, Zihuan Zhou, Qi Zhang, Qian Zhang, Dongjie Jiang, Shaohui He et al. · 2024 · Discover Oncology
  79. EpCAM deficiency causes the premature ageing of intestinal stem cells via EGFR/SP1/mTORC1 pathway
    Keying Li, Chang-Long Xu, Lulu Liu, Yunjuan Wang, Jun Chen, Chunyuan Li, Zitong Peng, Xiaoqian Li, Gang Chang, Zili Lei et al. · 2025 · Clinical and Translational Medicine
  80. Mitochondrial sirtuins at the crossroads of energy metabolism and oncogenic transformation
    Maja Grabacka, Przemyslaw Mieszko Plonka · 2021 · Elsevier eBooks
  81. Mechanisms of biological sensitivity and resistance to a rapidly changing ocean
    Tyler G. Evans, Cheryl A. Logan · 2019 · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
  82. In-depth Analysis of the Sirtuin 5-regulated Mouse Brain Acylome using Library-free Data-Independent Acquisitions
    Joanna Bons, Jacob Rose, Ran Zhang, Jordan B. Burton, Christopher Carrico, Eric M. Verdin, Birgit Schilling · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  83. Acetylation-Mediated Post-Translational Modification of Pyruvate Dehydrogenase Plays a Critical Role in the Regulation of the Cellular Acetylome During Metabolic Stress
    Aishwarya Rajakumar, Sarah C. Nguyen, Nicole Ford, Gbenga Ogundipe, Ethan Lopez-Nowak, Olena Kondrachuk, Manish Gupta · 2024 · Metabolites
  84. Nicotinamide Adenine Dinucleotide and Aging
    Zhi Jiang, Li Luo, Yuanyuan Qin, Yuyu Huang, Shuai Yan · 2025 · Springer eBooks
  85. Enteral nutrition intervention improves intestinal ischemia-reperfusion injury by modulating the SENP1/SIRT3 axis
    Shizhuang Wei, Zhenhua Li, Bo Wen, Wei Wang, Daolai Huang, Chao Zhang, Xianghua Wu · 2025 · Journal of Clinical Biochemistry and Nutrition
  86. The Role of Sirtuins in Cellular Senescence and the Development of Age-Associated Diseases
    V. A. Markelov, L. Z. Akhmadishina, О. В. Кочетова, В. В. Эрдман, Gulnaz Faritovna Korytina · 2025 · Russian Journal of Genetics
  87. Sirtuin-3 Regulates the Mechanism of Doxorubicin-induced Cardiotoxicity
    Cheng Zhang, Dan Shi, Ping Chang Yang · 2025 · International Heart Journal
  88. Integrated proteome, phospho-proteome and malonyl-proteome revealed a molecular alteration of breast cancer
    Chenxu Guo, Mingliang Zhang, Xin Jin, Chao Zhu, Rui Xu, Jiahe Sun, Jun Qian · 2025 · Scientific Reports
  89. The Role of Sirtuins in Improving Cardiovascular Function and the Prevention of Aging
    Rubi Duran, Manish A. Parikh, Amit Raizada, William H. Frishman, Stephen J. Peterson · 2025 · Cardiology in Review
  90. Sirtuin 5-mediated post-translational modifications as a promising therapeutic approach to attenuate liver diseases
    Yanqin Yue, Yuxin Ge, Rui Wang, Ge Qin, Bowen Fu, Xuemei Li, Wang Guo, Jinying Liu, Xingyuan Yang, Xiaoli Ma et al. · 2025 · European Journal of Pharmacology
  91. Beyond deacetylation: crosstalk mechanisms and context-dependent regulation of sirtuin non-classical enzymatic functions in disease
    Yiran Ma, Junli Chen, Ruixiao Song, Xiaolong Yu · 2026 · Molecular Medicine
  92. RND3 Enhances Cardiac Glucose Metabolism Through Inhibiting ACAT1-Dependent PDHA1 Acetylation and Protects Against Ischemia-Reperfusion Injury
    Zhenyu Xiong, Yueyang Li, Yan Zhang, Zhengjun Ma, Meiying Qi, H R Zhang, Xiaohua Zhang, Mengyuan Jiang, Jie Liu, Erhe Gao et al. · 2026 · Circulation
  93. Progress on mitochondrial silence information regulator family in epilepsy
    Feng ZHU, Yingchun Xiang, Linghui Zeng · 2021 · Journal of Zhejiang University (Medical Sciences)
  94. Lactate: an intracellular metabolite regulates cell cycle progression
    Jinke Cheng, Edward T.H. Yeh · 2023 · Life Metabolism
  95. Dethioacylation by Sirtuins 1–3: Considerations for Drug Design using Mechanism-based Sirtuin Inhibition
    Nima Rajabi, Alexander L. Nielsen, Christian Adam Olsen · 2019 · ChemRxiv
  96. Succinyl-CoA Synthetase Deficiency in Mouse Forebrain Results in Hyper-Succinylation With Perturbed Neuronal Transcriptional Regulation and Metabolism
    Makayla Suzanne Anderson, Emma H. Doud, Hongyu Gao, Duojiao Chen, Edward R. Simpson, Patrick J. Gillespie, Xiaona Chu, Marcus J. Miller, Yue Wang, Yunlong Liu et al. · 2022 · SSRN Electronic Journal
  97. Endogenous nucleophilic scavengers of reactive acyl-species neutralize carbon stress
    Min-Keun Lee, Seon Min Kim, Sanghyuk Lee, Jin Ho Yang, Chang-Ryul Choi, Ting Miao, Jong-Seo Kim, Norbert Perrimon, Yun Pyo Kang, Hyun‐Woo Rhee · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  98. Progress of Melatonin in Reducing Mitochondrial Injury by Interacting with Sirt3
    亚楠 胡 · 2019 · Advances in Clinical Medicine
  99. Protein Acetylation Induced by Dichloroacetate (DCA) Treatment is Associated with Decreased Respiration in Cultured Hepatocytes: Preliminary Results
    Jesse G. Meyer · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  100. Global profiles of a cetylated proteins in the brains of scrapie agents 139A- and ME7-infected mice collected at mid-early, mid-late and terminal stage
    Qi Shi, Dongdong Chen, Adalaiti Maimaitiming, Kang Xiao, Liping Gao, Xuehua Yang, Yue-Zhang Wu, Cao Chen, Xiao‐Ping Dong · 2020