Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
Best, Sarah A., De Souza, David P., Kersbergen, Ariena, Policheni, Antonia N., Dayalan, Saravanan, Tull, Dedreia, Rathi, Vivek, Gray, Daniel H., Ritchie, Matthew E., McConville, Malcolm J., Sutherland, Kate D.·2018·Cell Metabolism
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- Variant-informed multimodal tissue-state modeling reveals an NRF2 stress niche and dependency axis in KEAP1/NFE2L2-altered cancerMo-Wei Kong, Qiu-Ting Li, Xing-Wei Zhao, Yu Wang, Ya-Mei Luo, Yang Yu, Chun-Xiang Zhang · 2026 · Frontiers in Immunology
- BindingDB Entry 50010105: Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Inhibition: An Emerging Strategy in Cancer Therapy.BindingDB · 2021 · UC San Diego
- CUL3-mediated NRF2 dysregulation in TP53-driven non-small cell lung cancer: neddylation-associated structural perturbationsPoobana Dharmalingam, Chinnappan Sudandiradoss · 2026 · Frontiers in Bioinformatics