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Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides
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Functional Brown Adipose Tissue in Healthy Adults
Virtanen, K. A., Lidell, M. E., Orava, J., Heglind, M., Westergren, R., Niemi, T., Taittonen, M., Laine, J., Savisto, N.-J., Enerbäck, S., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808949 · Cited by 3,058
High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans
Saito, M., Okamatsu-Ogura, Y., Matsushita, M., Watanabe, K., Yoneshiro, T., Nio-Kobayashi, J., Iwanaga, T., Miyagawa, M., Kameya, T., Nakada, K., et al. (2009) · Diabetes · doi:10.2337/db09-0530 · Cited by 1,848
Liu, C., Wu, J., Zhu, J., Kuei, C., Yu, J., Shelton, J., Sutton, S. W., Li, X., Yun, S. J., Mirzadegan, T., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m806409200 · Cited by 606
Stimson, R. H., Anderson, A. J., Ramage, L. E., Macfarlane, D. P., de Beaux, A. C., Mole, D. J., Andrew, R., & Walker, B. R. (2017) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.12899 · Cited by 63
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Research works printed but not linked: 32
- Ahmed, 2010, An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81, Cell Metab., 11, 311, 10.1016/j.cmet.2010.02.012 · DOI
- Astrup, 1985, Contribution of BAT and skeletal muscle to thermogenesis induced by ephedrine in man, Am. J. Physiol., 248, E507
- Barbe, 2001, Measurements of white adipose tissue metabolism by microdialysis technique, Methods Mol. Biol., 155, 305
- Blondin, 2017, Inhibition of intracellular triglyceride lipolysis suppresses cold-induced brown adipose tissue metabolism and increases shivering in humans, Cell Metab., 25, 438, 10.1016/j.cmet.2016.12.005 · DOI · Paper page
- Blondin, 2015, Contributions of white and brown adipose tissues and skeletal muscles to acute cold-induced metabolic responses in healthy men, J. Physiol., 593, 701, 10.1113/jphysiol.2014.283598 · DOI
- Cannon, 1979, The physiological role of pyruvate carboxylation in hamster brown adipose tissue, Eur. J. Biochem., 94, 419, 10.1111/j.1432-1033.1979.tb12909.x · DOI
- Chakrabarty, 1983, Glycerokinase activity in human brown adipose tissue, J. Lipid Res., 24, 381, 10.1016/S0022-2275(20)37978-5 · DOI
- Chen, 2013, Brown fat activation mediates cold-induced thermogenesis in adult humans in response to a mild decrease in ambient temperature, J. Clin. Endocrinol. Metab., 98, E1218, 10.1210/jc.2012-4213 · DOI
- Chondronikola, 2016, Brown adipose tissue activation is linked to distinct systemic effects on lipid metabolism in humans, Cell Metab., 23, 1200, 10.1016/j.cmet.2016.04.029 · DOI
- Cypess, 2015, Activation of human brown adipose tissue by a beta3-adrenergic receptor agonist, Cell Metab., 21, 33, 10.1016/j.cmet.2014.12.009 · DOI · Paper page
- Din, 2016, Human brown adipose tissue [(15)O]O2 PET imaging in the presence and absence of cold stimulus, Eur. J. Nucl. Med. Mol. Imaging, 43, 1878, 10.1007/s00259-016-3364-y · DOI
- Goossens, 2008, Human adipose tissue blood flow and micromanipulation of human subcutaneous blood flow, Methods Mol. Biol., 456, 97, 10.1007/978-1-59745-245-8_7 · DOI
- Hao, 2015, Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism, Am. J. Physiol. Endocrinol. Metab., 308, E380, 10.1152/ajpendo.00277.2014 · DOI
- Hu, 2013, Characterization of human brown adipose tissue by chemical-shift water-fat MRI, AJR Am. J. Roentgenol., 200, 177, 10.2214/AJR.12.8996 · DOI
- Janderova, 2003, Human mesenchymal stem cells as an in vitro model for human adipogenesis, Obes. Res., 11, 65, 10.1038/oby.2003.11 · DOI · Paper page
- Jensen, 2007, In vivo and in vitro microdialysis sampling of free fatty acids, J. Pharm. Biomed. Anal., 43, 1751, 10.1016/j.jpba.2006.12.014 · DOI
- Kiskinis, 2014, RIP140 represses the “brown-in-white” adipocyte program including a futile cycle of triacylglycerol breakdown and synthesis, Mol. Endocrinol., 28, 344, 10.1210/me.2013-1254 · DOI
- Labbe, 2015, In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis, FASEB J., 29, 2046, 10.1096/fj.14-266247 · DOI
- Lee, 2011, Hot fat in a cool man: infrared thermography and brown adipose tissue, Diabetes Obes. Metab., 13, 92, 10.1111/j.1463-1326.2010.01318.x · DOI
- Lee, 2014, Temperature-acclimated brown adipose tissue modulates insulin sensitivity in humans, Diabetes, 63, 3686, 10.2337/db14-0513 · DOI
- Ma, 1986, Uptake of glucose and release of fatty acids and glycerol by rat brown adipose tissue in vivo, Can. J. Physiol. Pharmacol., 64, 609, 10.1139/y86-101 · DOI
- Macfarlane, 2014, Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with type 2 diabetes with and without fatty liver, Am. J. Physiol. Gastrointest. Liver Physiol., 307, G760, 10.1152/ajpgi.00030.2014 · DOI
- Muller, 1996, Measurement of interstitial muscle glucose and lactate concentrations during an oral glucose tolerance test, Am. J. Physiol., 271, E1003
- Muzik, 2013, 15O PET measurement of blood flow and oxygen consumption in cold-activated human brown fat, J. Nucl. Med., 54, 523, 10.2967/jnumed.112.111336 · DOI
- Nagao, 2017, Increased dynamics of tricarboxylic acid cycle and glutamate synthesis in obese adipose tissue: in vivo metabolic turnover analysis, J. Biol. Chem., 292, 4469, 10.1074/jbc.M116.770172 · DOI
- Orava, 2011, Different metabolic responses of human brown adipose tissue to activation by cold and insulin, Cell Metab., 14, 272, 10.1016/j.cmet.2011.06.012 · DOI · Paper page
- Ouellet, 2012, Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans, J. Clin. Invest., 122, 545, 10.1172/JCI60433 · DOI · Paper page
- Raiko, 2015, Brown adipose tissue triglyceride content is associated with decreased insulin sensitivity, independently of age and obesity, Diabetes Obes. Metab., 17, 516, 10.1111/dom.12433 · DOI
- Ramage, 2016, Glucocorticoids acutely increase brown adipose tissue activity in humans, revealing species-specific differences in UCP-1 regulation, Cell Metab., 24, 130, 10.1016/j.cmet.2016.06.011 · DOI
- Rosdahl, 1998, Metabolite levels in human skeletal muscle and adipose tissue studied with microdialysis at low perfusion flow, Am. J. Physiol., 274, E936
- Stahle, 1991, A comparison between three methods for estimation of extracellular concentrations of exogenous and endogenous compounds by microdialysis, J. Pharmacol. Methods, 25, 41, 10.1016/0160-5402(91)90021-V · DOI
- Yoneshiro, 2011, Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men, Obesity (Silver Spring), 19, 13, 10.1038/oby.2010.105 · DOI
Metadata
- Authors
- Weir, G., Ramage, L. E., Akyol, M., Rhodes, J. K., Kyle, C. J., Fletcher, A. M., Craven, T. H., Wakelin, S. J., Drake, A. J., Gregoriades, M.-L., Ashton, C., Weir, N., van Beek, E. J. R., Karpe, F., Walker, B. R., & Stimson, R. H.
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2018-06
- Volume
- 27
- Issue
- 6
- Pages
- 1348-1355.e4
- ISSN
- 1550-4131
- Cited by
- 133
- References
- 4
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- creativecommons.org/licenses/by/4.0/ (vor)
- Funders
- National Rosacea Society
- Wellcome Trust (107049/Z/15/Z)
- Medical Research Council (MR/K010271/1)
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.