Process modeling of recombinant adeno-associated virus production in HEK293 cells
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Registry
Cites
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Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Most existing viral vector models are vector specific and typically require re-derivation or extensive re-parameterization when applied to other viral systems.
“Most existing models are vector specific and typically require re-derivation or extensive re-parameterization when applied to other viral systems.”
From Mechanistic model for HEK293 viral vector processes and its application in a digital shadow framework (2026) · cites this paper as [5]
For AAV, several mechanistic frameworks describe triple transfection dynamics, cell growth, metabolism, genome replication, and capsid formation.
“For AAV, several mechanistic frameworks describe triple transfection dynamics, cell growth, metabolism, genome replication, and capsid formation [5, 16, 17].”
From Mechanistic model for HEK293 viral vector processes and its application in a digital shadow framework (2026) · cites this paper as [5]
Several mechanistic modeling efforts have characterized HEK293 based viral vector production, although most of them remain vector specific.
“Several mechanistic modeling efforts have characterized HEK293 based viral vector production, although most of them remain vector specific.”
From Mechanistic model for HEK293 viral vector processes and its application in a digital shadow framework (2026) · cites this paper as [5]
Cites
A community-driven global reconstruction of human metabolism
Thiele, I., Swainston, N., Fleming, R. M. T., Hoppe, A., Sahoo, S., Aurich, M. K., Haraldsdottir, H., Mo, M. L., Rolfsson, O., Stobbe, M. D., et al. (2013) · Nature Biotechnology · doi:10.1038/nbt.2488 · Cited by 1,019 · see citing works
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Cited by
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Kuchemüller, K. B., Austerjost, J., Machleid, R., Roßkamp, A., Niemann, J., & McCready, C. (2026) · Bioprocess and Biosystems Engineering · doi:10.1007/s00449-026-03362-2
- Authors
- Joiner, J., Huang, Z., McHugh, K., Stebbins, M., Aron, K., Borys, M., & Khetan, A.
- Venue
- Current Opinion in Chemical Engineering
- Publisher
- Elsevier BV
- Published
- 2022-06
- Volume
- 36
- Pages
- 100823
- ISSN
- 2211-3398
- Cited by
- 18
- References
- 1
- Language
- en
- Licence
- Funders
- Bristol-Myers Squibb
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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