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Bactericidal effect of graphene oxide and reduced graphene oxide: Influence of shape of bacteria

Sengupta, Iman, Bhattacharya, Proma, Talukdar, Monikangkana, Neogi, Sudarsan, Pal, Surjya K., Chakraborty, Sudipto·2019·Colloid and Interface Science Communications

Abstract

Abstract The emergence of multi-drug resistant bacteria due to the misuse of antibiotics and inadequate development of antibiotic drugs is a global threat to human health. Recent development in materials research caused the emergence of nanomaterials with promising bactericidal properties. Carbon based nanomaterials like graphene and graphene oxide(GO) have appealed researchers for antimicrobial properties, although some researchers claimed that they promote bacteria growth. To address the conflict, authors performed experiments to study the influence of GO and reduced GO(rGO) on gram positive Staphylococcus aureus and gram negative Pseudomonas aeruginosa bacteria. GO restricts S. aureus and P. aeruginosa cell growth by 93.7% and 48.6% whereas, percentage inhibition by rGO are 67.7% and 93.3% respectively. GO destructs bacteria by cell membrane damage through chemical reaction whereas, rGO induce mechanical stress and pierce the cell membrane. Shape and type of bacteria act as the controlling factors in determining the bactericidal efficacy of the nanomaterials.

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Metadata

Authors
Sengupta, I., Bhattacharya, P., Talukdar, M., Neogi, S., Pal, S. K., & Chakraborty, S.
Venue
Colloid and Interface Science Communications
Publisher
Elsevier BV
Published
2019-01
Volume
28
Pages
60-68
ISSN
2215-0382 (ISSN-L)
OpenAlex
W2905966424
Cited by
199
References
2
FWCI
5.10
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Bactericidal effect of graphene oxide and reduced graphene oxide: Influence of shape of bacteria. https://app.cochat.ai/papers/10.1016/j.colcom.2018.12.001
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Sengupta, I., Bhattacharya, P., Talukdar, M., Neogi, S., Pal, S. K., & Chakraborty, S. (2019). Bactericidal effect of graphene oxide and reduced graphene oxide: Influence of shape of bacteria. Colloid and Interface Science Communications. https://doi.org/10.1016/j.colcom.2018.12.001

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