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Multi-modal vertebrae recognition using Transformed Deep Convolution Network
Abstract
Automatic vertebra recognition, including the identification of vertebra locations and naming in multiple image modalities, are highly demanded in spinal clinical diagnoses where large amount of imaging data from various of modalities are frequently and interchangeably used. However, the recognition is challenging due to the variations of MR/CT appearances or shape/pose of the vertebrae. In this paper, we propose a method for multi-modal vertebra recognition using a novel deep learning architecture called Transformed Deep Convolution Network (TDCN). This new architecture can unsupervisely fuse image features from different modalities and automatically rectify the pose of vertebra. The fusion of MR and CT image features improves the discriminativity of feature representation and enhances the invariance of the vertebra pattern, which allows us to automatically process images from different contrast, resolution, protocols, even with different sizes and orientations. The feature fusion and pose rectification are naturally incorporated in a multi-layer deep learning network. Experiment results show that our method outperforms existing detection methods and provides a fully automatic location+naming+pose recognition for routine clinical practice.
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“While a survey on deep learning in medical image analysis has shown a wide variety of applications in all imaging subspecialties (13), applications in musculoskeletal imaging remain limited (14–17).”
From Deep learning approach for evaluating knee MR images: achieving high diagnostic performance for cartilage lesion detection. (2018) · cites this paper as [15]
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Research works printed but not linked: 9
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- Major, 2013, Automated landmarking and labeling of fully and partially scanned spinal columns in CT images, Med Image Anal, 17, 1151, 10.1016/j.media.2013.07.005 · DOI
- Štern, 2010, Automated detection of spinal centrelines, vertebral bodies and intervertebral discs in CT and MR images of lumbar spine, Phys Med Biol, 55, 247, 10.1088/0031-9155/55/1/015 · DOI
- Kelm, 2013, Spine detection in CT and MR using iterated marginal space learning, Med Image Anal, 17, 1283, 10.1016/j.media.2012.09.007 · DOI
- Alomari, 2011, Labeling of lumbar discs using both pixel- and object-level features with a two-level probabilistic model, IEEE Trans Med Imaging, 30, 1, 10.1109/TMI.2010.2047403 · DOI
- Cai, 2013, Detecting, grouping, and structure inference for invariant repetitive patterns in images, IEEE Trans Image Process, 22, 2343, 10.1109/TIP.2013.2251649 · DOI
- Oktay, 2013, Simultaneous localization of lumbar vertebrae and intervertebral discs with SVM-based MRF, IEEE Trans BME, 60, 2375, 10.1109/TBME.2013.2256460 · DOI
- Ma, 2013, Hierarchical segmentation and identification of thoracic vertebra using learning-based edge detection and coarse-to-fine deformable model, Comput Vis Image Underst, 117, 1072, 10.1016/j.cviu.2012.11.016 · DOI
- Cai, 2015, Multi-modality vertebra recognition in arbitrary views using 3D deformable hierarchical model, IEEE Trans Med Imaging, 34, 1676, 10.1109/TMI.2015.2392054 · DOI
Cited by
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A survey on deep learning in medical image analysis
Litjens, G., Kooi, T., Bejnordi, B. E., Setio, A. A. A., Ciompi, F., Ghafoorian, M., van der Laak, J. A. W. M., van Ginneken, B., & Sánchez, C. I. (2017) · Medical Image Analysis · doi:10.1016/j.media.2017.07.005 · Cited by 15,332
Liu, F., Zhou, Z., Samsonov, A., Blankenbaker, D., Larison, W., Kanarek, A., Lian, K., Kambhampati, S., & Kijowski, R. (2018) · Radiology · doi:10.1148/radiol.2018172986 · Cited by 297
Metadata
- Authors
- Cai, Y., Landis, M., Laidley, D. T., Kornecki, A., Lum, A., & Li, S.
- Affiliations
- Western University (CA)
- Corresponding author
- Li, Shuo
- Venue
- Computerized Medical Imaging and Graphics
- Publisher
- Elsevier BV
- Published
- 2016-07
- Volume
- 51
- Pages
- 11-19
- ISSN
- 0730-4862 (ISSN-L)
- 0895-6111
- OpenAlex
- W2321283863
- Cited by
- 95
- References
- 0
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 8 · 2023: 7 · 2022: 13 · 2021: 13 · 2020: 13 · 2019: 17 · 2018: 9 · 2017: 7 · 2016: 1
- FWCI
- 5.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Computerized Medical Imaging and Graphics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Medical Imaging and Analysis
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Advanced Neural Network Applications
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
- Keywords
- multimodal image fusion, spinal imaging
- MeSH terms
- Machine Learning, Automation, Humans, Spine
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