New insights on the role of microglia in synaptic pruning in health and disease
Cited by (558)
Items 501–558 of 558
- Author response: Human iPSC-derived Microglial Cells Integrated into Mouse Retina and Recapitulated Features of Endogenous MicrogliaWenxin Ma, Lian Zhao, Biying Xu, Robert N. Fariss, T. Michael Redmond, Jizhong Zou, Wai T. Wong, Wei Li · 2024 · eLife
- Microglia are Required for Developmental Specification of AgRP Innervation in the Hypothalamus of Offspring Exposed to Maternal High Fat Diet During LactationHaley N Mendoza-Romero, Jessica E. Biddinger, Michelle N. Bedenbaugh, Richard B. Simerly · 2024 · eLife
- Novel fluorinated cannabinoid analogs modulate cytokine expression in human C20 microglial cellsRandall L. Davis, Sascha Grotjahn, Burkhard König, Daniel J. Buck, Jimmie D. Weaver · 2024 · Pharmacological Reports
- Reduced levels of synaptic vesicle protein 2A in the extracellular vesicles and brain of Alzheimer’s disease- associations with Aβ, tau and synaptophysinJana Nussbaumer, Aatmika Barve, Valentin Zufferey, Jeanne Espourteille, Tunahan Kirabali, Uwe Konietzko, Daniel Razansky, Axel Rominger, Agneta K. Nordberg, Luc Buée et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Crosstalk between gut-brain axis and brain components along with associated neurological disordersPriya Bindal, Swati Kaushal, Charan Singh, Arti Singh · 2025 · Elsevier eBooks
- Microglia are Required for Developmental Specification of AgRP Innervation in the Hypothalamus of Offspring Exposed to Maternal High-Fat Diet During LactationHaley N Mendoza-Romero, Jessica E. Biddinger, Michelle N. Bedenbaugh, Richard B. Simerly · 2025 · eLife
- A schizophrenia-associated radial glia cell state perturbs early human brain developmentSusmita Malwade, Samudyata Samudyata, Jessica Gracias Lekander, Angelika Langeder, Katharina Weinberger, Marja Koskuvi, Ana Osório Oliveira, Šárka Lehtonen, Luis Enrique Arroyo‐García, Aiden Peter Corvin et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- G-protein coupled receptor chemokine CX3CR1 influences extracellular Tau internalization in Alzheimer’s diseaseSubashchandrabose Chinnathambi, Nagaraj Rangappa, Madhura Chandrashekar · 2025 · Advances in protein chemistry and structural biology
- Additional file 3 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 3 of Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3Wenzhi Hao, Ma, Qingyu, Wang, Lu, Naijun Yuan, Hua Tian Gan, He, Liangliang, Li, Xiaojuan, Huang, Junqing, Jiaxu Chen · 2024 · Figshare
- Additional file 2 of Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3Wenzhi Hao, Ma, Qingyu, Wang, Lu, Naijun Yuan, Hua Tian Gan, He, Liangliang, Li, Xiaojuan, Huang, Junqing, Jiaxu Chen · 2024 · Figshare
- Additional file 1 of Functional role of brain-engrafted macrophages against brain injuriesXi Feng, Elma S. Frias, Paladini, Maria S., David Chen, Zoe Boosalis, McKenna Becker, Sonali Gupta, Liu, Sharon, Gupta, Nalin, Rosi, Susanna · 2021 · Figshare
- Additional file 1 of Intermittent hypoxia exacerbates anxiety in high-fat diet-induced diabetic mice by inhibiting TREM2-regulated IFNAR1 signalingWenyu Ni, Niu, Yun, Sitong Cao, Fan, Chunsun, Jian Fan, Zhu, Li, Xueting Wang · 2024 · Figshare
- Additional file 5 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 1 of Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3Wenzhi Hao, Ma, Qingyu, Wang, Lu, Naijun Yuan, Hua Tian Gan, He, Liangliang, Li, Xiaojuan, Huang, Junqing, Jiaxu Chen · 2024 · Figshare
- Additional file 4 of Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3Wenzhi Hao, Ma, Qingyu, Wang, Lu, Naijun Yuan, Hua Tian Gan, He, Liangliang, Li, Xiaojuan, Huang, Junqing, Jiaxu Chen · 2024 · Figshare
- Additional file 8 of Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3Wenzhi Hao, Ma, Qingyu, Wang, Lu, Naijun Yuan, Hua Tian Gan, Liangliang He, Li, Xiaojuan, Huang, Junqing, Jiaxu Chen · 2024 · Figshare
- Additional file 1 of Neuronal hibernation following hippocampal demyelinationSelva Baltan, Safdar Jawaid, Anthony M. Chomyk, Grahame J. Kidd, Chen, Jacqueline, Harsha D. Battapady, Chan, Ricky, Ranjan Dutta, Trapp, Bruce D. · 2021 · Figshare
- Additional file 1 of IL-1R/C3aR signaling regulates synaptic pruning in the prefrontal cortex of depressionZhang, Man-Man, Guo, Min-Xia, Zhang, Qiu-Ping, Chen, Xue-Qin, Li, Na-Zhi, Liu, Qing, Cheng, Jie, Wang, Shi-Le, Xu, Guang-Hui, Li, Cheng-Fu et al. · 2022 · Figshare
- Additional file 1 of Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsicFrancesca Logiacco, Laura Cathleen Grzegorzek, Elizabeth Cordell, Oliver Popp, Mertins, Philipp, David H. Gutmann, Helmut Kettenmann, Marcus Semtner · 2023 · Figshare
- Additional file 2 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 2 of Intermittent hypoxia exacerbates anxiety in high-fat diet-induced diabetic mice by inhibiting TREM2-regulated IFNAR1 signalingWenyu Ni, Niu, Yun, Sitong Cao, Fan, Chunsun, Jian Fan, Zhu, Li, Xueting Wang · 2024 · Figshare
- Additional file 7 of Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3Wenzhi Hao, Ma, Qingyu, Wang, Lu, Naijun Yuan, Hua Tian Gan, Liangliang He, Li, Xiaojuan, Huang, Junqing, Jiaxu Chen · 2024 · Figshare
- Additional file 6 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 1 of Pyruvate kinase isoform M2 impairs cognition in systemic lupus erythematosus by promoting microglial synaptic pruning via the β-catenin signaling pathwayLi Lu, Wang, Hailin, Liu, Xuan, Tan, Liping, Xiaoyue Qiao, Jiali Ni, Sun, Yang, Jun Liang, Hou, Yayi, Huan Dou · 2021 · Figshare
- Additional file 4 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 5 of Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3Wenzhi Hao, Ma, Qingyu, Wang, Lu, Naijun Yuan, Hua Tian Gan, He, Liangliang, Li, Xiaojuan, Huang, Junqing, Jiaxu Chen · 2024 · Figshare
- Additional file 1 of Microglia/macrophages are ultrastructurally altered by their proximity to spinal cord injury in adult female miceSt-Pierre, Marie-Kim, Fernando Gonzàlez Ibáñez, Antje Kroner, Marie‐Ève Tremblay · 2024 · Figshare
- Additional file 1 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 6 of Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3Wenzhi Hao, Ma, Qingyu, Wang, Lu, Naijun Yuan, Hua Tian Gan, Liangliang He, Li, Xiaojuan, Huang, Junqing, Jiaxu Chen · 2024 · Figshare
- Additional file 2 of Microglia/macrophages are ultrastructurally altered by their proximity to spinal cord injury in adult female miceSt-Pierre, Marie-Kim, Fernando Gonzàlez Ibáñez, Antje Kroner, Marie‐Ève Tremblay · 2024 · Figshare
- Endurance training mitigates obesity-induced hippocampal impairment by enhancing neurotrophin signalling, synaptic plasticity, and cellular responses in a female rat modelTomáš Kuruc, Karolı́na Kuchárová, Alexandra Kisucká, Mária Ileninová, Lenka Ihnátová, Katarína Bimbová, Martina Magurova, Ján Gálik, Nadežda Lukáčová · 2026 · IBRO Neuroscience Reports
- The influence of the gut-brain axis on neurological and psychiatric well-beingMuhammad Sufyan, Mohammad Amjad Kamal · 2025 · Asia-Pacific Journal of Surgical & Experimental Pathology
- A multimodal single-cell atlas of the adolescent brain reveals gene regulatory networks linking development to disease riskIsabella C. Galvão, Manuela Lemoine, Tomás Vega Waichman, Bhavyaa Chandarana, Steven Hébert, Thaís Crippa de Oliveira, Luciano H. B. dos Santos, Fábio Rogério, Clarissa Lin Yasuda, Enrico Ghizoni et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Ddx20, DEAD-box helicase 20 is essential for maintaining microglial homeostasisYosuke Kawai, Norihisa Bizen, Kei Nishiyama, Hirohide Takebayashi · 2026 · Experimental Neurology
- In vitro and in vivo study of the effects of Levetiracetam on activated microglia during sepsisRenaud Fleurance · 2021 · theses.fr (ABES)
- Role of astrocytic calcium signaling in synaptic transmission, plasticity and memory : implications for neurodegenerative diseasesElsie Moukarzel · 2021 · theses.fr (ABES)
- Influence des lipides membranaires sur les interactions protéiques liées aux anomalies endolysosomales dans un modèle neuronal de la maladie d'AlzheimerMaxime Vigier · 2022 · theses.fr (ABES)
- Post‐Mortem Delay Induces Distinct Transcriptional and Morphological Changes in Microglia With Age‐Specific PatternsStanislav O. Kozlov, Eduard Schmidt, Heidi Theis, Elena De Domenico, Marc Beyer, Annett Halle · 2026 · Glia
- Hétérogénéité et régulation des astrocytes dans la maladie d'Alzheimer : vers des interventions ciblées sur les voies JAK2-STAT3 et NF-kBYiannis Poulot-Becq-Giraudon · 2024 · theses.fr (ABES)
- Myelin alterations in early stages of Alzheimer's disease and preclinical assessment of the protective and therapeutic potential of neurosteroid 3α-O-allyl-allopregnanoloneNwife Getrude Okechukwu · 2023 · theses.fr (ABES)
- Adolescent Astrocyte Dysregulation Impairs Prefrontal Interneuron Maturation and Adult CognitionJohanna Furrer, Viktor Beilmann, Anna Cavaccini, Eliane Boesch, Sina M. Schalbetter, Ali Özgür Argunşah, Sarai Fischer, Aurelia Portmann, Olga Krzyzaniak, Felipe Velasquez Moros et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- TGM2 drives microglial senescence by inhibiting autophagy via the PI3K/AKT/mTORC1 pathwayZhiqiang Li, Yuxiang Tang, Dongyuan Zhang, Jiayi Li, Tianxiang Wang, Qiuxia Pan, Xianbin Meng, Xiaolin Tian, Haiteng Deng · 2026 · Free Radical Biology and Medicine
- Maternal palmitoleic acid supplementation attenuates neurodegenerative programming in aged offspring exposed to gestational diabetesRitsuko Kawaharada, Reiko Kimura, Eri Miyata, Reona Noguchi, Akiyo Toriumi, Akio Nakamura · 2026 · Nutrients
- C1qa□ muscularis macrophages maintain enteric synaptic homeostasis to regulate gastrointestinal motilityMario D’Ambrosio, Juan Sebastian Ortiz Colmenares, Khaled Warasnhe, Yuanhang Liu, Mohamed H. Eldesouki, Vladimir Dokic, Natalie R. Wertish, Xinyi Chai, Sara Traserra, Trace A. Christensen et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Maresin-1 protects against lipopolysaccharide (LPS)-induced depressive-like behavior in adolescent mice and promotes M2 microglial polarization via ERK/NF-κB signalingGuo J, Xiang Cao, Chenxi Liu, Feng Chen, Zixuan Ye, Tian Qiu · 2026 · European Journal of Pharmacology
- Microbiome-derived Short Chain Fatty Acids modulate microglial inflammatory responses in a sex- and metabolite-specific mannerMorgan Towriss, Vivien Dang, Jenna Goeres, Jatin Choudhary, Alison Aube, Juliana Montoya Sanchez, Clianta Anindya, Koyah Morgan-Banke, Jordan E. Hamden, Christopher Whidbey et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Coherence-incoherence patterns in coupled excitable systemsIgor Franović, Sebastian Eydam, Jinjie Zhu, Семенова Надежда Игоревна, Frederico P. Costa, Eckehard Schöll · 2026 · Physics of Life Reviews
- Neuroplasticity and immune system are related to altered grey matter networks: a cohort study in sporadic Alzheimer’s diseaseDiederick M de Leeuw, Flora Hillegonde Duits, Ellen Dicks, Eleonora M. Vromen, Charlotte Elisabeth Teunissen, Frederik Barkhof, Wiesje M. van der Flier, Pieter Jelle Visser, Betty Marije Tijms · 2026 · Brain Communications
- Microglial synaptic pruning in early Alzheimer’s disease: emerging roles of the IL-1β-NLRP3 axisArjun Singh Kaushik, Nitin Singh · 2026 · Inflammopharmacology
- L-fucose administration ameliorates chronic social defeat stress-induced depressive-like behaviors by restoring GDP-fucose biosynthetic activation and core fucosylationMeng Zheng, Tomohiko Fukuda, Siming Zhang, Yue Wang, Tsukushi Saito, Yuhang Zhou, Boyu Xia, Kazuki Mochizuki, Teruki Aizawa, Tomoya Isaji et al. · 2026 · Frontiers in Immunology
- Therapeutic strategies in prion disease: current evidence, translational challenges, and emerging directionsYi-Xin Zhu, Barry M. Bradford, N. Mabbott · 2026 · Frontiers in Neuroscience
- A Cross-Region Meta-Analysis and Machine Learning Identifies a 37-Gene Signature Associated with Alzheimer’s DiseaseKashvi Chirag Shah, Ethan Daniel Littlestone, Md Roungu Ahmmad, Chunmei Wang, Yong Xu, Xiaoli Zhang · 2026 · Biomedicines
- Autophagy-lysosomal pathway in neurodegenerationSamantha R. McDonough, Aditya K. Rao, Jacqueline M. McAleer, Bergan M. Babrowicz, Manu Sharma · 2026 · Molecular Neurodegeneration Advances
- Integrative synaptosome multi-omics reveals disrupted synapse organization and localized cryptic transcripts in C9ORF72-frontotemporal dementiaAshton M Spillman, Eric B. Alsop, Lauren M. Gittings, Krystine Garcia‐Mansfield, Ignazio Stefano Piras, Anna Bonfitto, Melissa N. Martinez, Ritin Sharma, Kim R Preller, Matthew J. Huentelman et al. · 2026 · Acta Neuropathologica
- Remodeling of the brain immune microenvironment in Alzheimer’s disease: interactions among microglia, astrocytes, complement, and the neurovascular unitTong Wang, Lu Wang, Jianing Cao, Yi Zhao, Zongling He, Fengmei Lu · 2026 · Frontiers in Immunology
- Transient synaptic refinement and glial adaptations after whisker denervation in adult miceSean Collier, Laxmi Iyer, Kimberly R. Byrnes, Emily Petrus · 2026 · Frontiers in Cellular Neuroscience
- A statistical framework for integrative imaging genomics with biclustering and ensemble penalized regression in Alzheimer’s diseaseHao Chen, He Yong, Lei Hou, Lei Liu, Chencheng Ma · 2026 · NeuroImage