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Cited by 14Physiological and biochemical adaptationsNeurobiology and Insect Physiology ResearchNeuroscience and Neuropharmacology Research

Resilience of circuits to environmental challenge

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Schapiro, Kyra, Marder, Eve·2024·Current Opinion in Neurobiology
DOI 10.1016/j.conb.2024.102885PMC PMC11316650
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Abstract

Animals of all kinds evolved to deal with anticipated and unanticipated changes in a variety of features in their environments. Consequently, all environmental perturbations, adaptations, and acclimation involve a myriad of factors that, together, contribute to environmental resilience. New work highlights the importance of neuromodulation in the control of environmental resilience, and illustrates that different components of the nervous system may be differentially resilient to environmental perturbations. Climate change is today pushing animals to deal with previously unanticipated environmental challenges, and therefore understanding the complex biology of adaptation and acclimation to various environmental conditions takes on new urgency.

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  • Many biological processes vary considerably over 4-5 °C, well within the range of what is normally considered room temperature.

    “because many biological processes vary considerably over 4-5 • C [40,55-59], well within the range of what is normally considered room temperature.”

    From A feature and not a bug: Replication failures can lead to new biology (2026) · cites this paper as [58]

    The Introduction section “Temperature and pH Change Dynamics of Neuronal and Circuit Function” (page unavailable) says temperature affects most biological molecules and that even very small changes can alter neuronal network behavior. It does not establish that many biological processes vary considerably over a 4–5 °C interval or discuss that interval as part of room temperature. (LLM, conf=0.86)

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Cited by

Sorted by citations

Authors
Schapiro, K., & Marder, E.
Affiliations
Brandeis University (US)
Corresponding author
Marder, Eve
ORCID
Venue
Current Opinion in Neurobiology
Publisher
Elsevier BV
Published
2024-08
Volume
87
Pages
102885
ISSN
0959-4388 (ISSN-L)
DOI
10.1016/j.conb.2024.102885
PMC
PMC11316650
OpenAlex
W4399474183
Cited by
14
References
2
Citations by year
2026: 8 · 2025: 4 · 2024: 2
FWCI
0.64
Type
journal article
Language
en
Open access
Licence
Locations
  • Current Opinion in Neurobiology (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institutes of Health
Topics
  • Physical Sciences › Environmental Science › Ecology › Physiological and biochemical adaptations
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
environmental resilience, neuromodulation, environmental disturbance, adaptation, acclimation, climate change, nervous system, animal behavior
MeSH terms
Acclimatization, Adaptation, Physiological, Animals, Environment, Humans, Climate Change

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