A green light for engineered algae: redirecting metabolism to fuel a biotechnology revolution
Abstract
Microalgae have the potential to revolutionize biotechnology in a number of areas including nutrition, aquaculture, pharmaceuticals, and biofuels. Although algae have been commercially cultivated for over 50 years, metabolic engineering now seems necessary in order to achieve their full processing capabilities. Recently, the development of a number of transgenic algal strains boasting recombinant protein expression, engineered photosynthesis, and enhanced metabolism encourage the prospects of designer microalgae. Given the vast contributions that these solar-powered, carbon dioxide-sequestering organisms can provide to current global markets and the environment, an intensified focus on microalgal biotechnology is warranted. Ongoing advances in cultivation techniques coupled with genetic manipulation of crucial metabolic networks will further promote microalgae as an attractive platform for the production of numerous high-value compounds.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Algae production strains have the potential to be bioengineered, allowing improvement of specific traits and production of valuable co-products, which may allow algal biofuels to compete economically with petroleum.
“Algae production strains also have the potential to be bioengineered, allowing improvement of specific traits [25,26] and production of valuable co-products, which may allow algal biofuels to compete economically with petroleum.”
From Biofuels from algae: Challenges and potential (2010) · cites this paper as [25]
Many industrial enzymes can be produced with values ranging between $25 and $50 per kg, and large markets currently exist for them.
“there are many industrial enzymes that can be produced, with values ranging between $25 and $50 per kg, and for which large markets currently exist [25]”
From Biofuels from algae: Challenges and potential (2010) · cites this paper as [25]
The citation lists haven’t been fetched yet
References 58 · Cited by 631
- Authors
- Rosenberg, J. N., Oyler, G. A., Wilkinson, L., & Betenbaugh, M. J.
- Affiliations
- Johns Hopkins University (US)
- Corresponding author
- Rosenberg, Julian N
- Oyler, George A
- Wilkinson, Loy
- Betenbaugh, Michael J
- Venue
- Current Opinion in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2008-10
- Volume
- 19
- Issue
- 5
- Pages
- 430-436
- ISSN
- 0958-1669 (ISSN-L)
- OpenAlex
- W2139554559
- Cited by
- 631
- References
- 58
- Citations by year
- 2026: 6 · 2025: 16 · 2024: 22 · 2023: 21 · 2022: 32 · 2021: 20 · 2020: 25 · 2019: 39 · 2018: 35 · 2017: 37 · 2016: 52 · 2015: 49 · 2014: 45 · 2013: 60 · 2012: 53
- FWCI
- 1.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Keywords
- microalgae, metabolic engineering, transgenic algae, recombinant protein expression, biofuels, algae cultivation, CO2 sequestration, aquaculture feed, pharmaceuticals
- MeSH terms
- Bioelectric Energy Sources, Biotechnology, Conservation of Natural Resources, Forecasting, Genetic Engineering, Recombinant Proteins, Metabolomics, Eukaryota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
