Biosensors for the monitoring of harmful algal blooms

Progress in Understanding Harmful Algal Blooms: Paradigm Shifts and New Technologies for Research, Monitoring, and Management

Anderson, D. M., Cembella, A. D., & Hallegraeff, G. M. (2012) · Annual Review of Marine Science · doi:10.1146/annurev-marine-120308-081121 · Cited by 1,165

The re-eutrophication of Lake Erie: Harmful algal blooms and hypoxia

Watson, S. B., Miller, C. J., Arhonditsis, G. B., Boyer, G. L., Carmichael, W. W., Charlton, M. N., Confesor, R., Depew, D. C., Höök, T. O., Ludsin, S. A., et al. (2016) · Harmful Algae · doi:10.1016/j.hal.2016.04.010 · Cited by 699

A watery arms race

Smetacek, V. S. (2001) · Nature · doi:10.1038/35081210 · Cited by 235

Toxicity assessment using different bioassays and microbial biosensors

Hassan, S. H. A., Ginkel, S. W. V., Hussein, M. A., Abskharon, R. N. N., & Oh, S. (2016) · Environment International · doi:10.1016/j.envint.2016.03.003 · Cited by 174

Remote Detection of Marine Microbes, Small Invertebrates, Harmful Algae, and Biotoxins using the Environmental Sample Processor (ESP)

Scholin, C. A., Doucette, G. J., Jensen, S. D., Roman, B., Pargett, D. M., Marin, R., Preston, C. M., Jones, W., Feldman, J., Everlove, C., et al. (2009) · Oceanography · doi:10.5670/oceanog.2009.46 · Cited by 160

Formation of harmful algal blooms cannot be explained by allelopathic interactions

Jonsson, P. R., Pavia, H., & Toth, G. B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900964106 · Cited by 154

Algal bloom and its economic impact

Sanseverino, I., Sofia, C. A. D., Pozzoli, L., Dobricic, S., & Lettieri, T. (2016) · Joint Research Centre (European Commission) · doi:10.2788/660478 · Cited by 152

Field applications of the second‐generation Environmental Sample Processor (ESP) for remote detection of harmful algae: 2006‐2007

Greenfield, D. I., Marin, R., Doucette, G. J., Mikulski, C. M., Jones, K. L., Jensen, S. D., Roman, B., Alvarado, N., Feldman, J., & Scholin, C. A. (2008) · Limnology and Oceanography Methods · doi:10.4319/lom.2008.6.667 · Cited by 93

Application of environmental sample processor (ESP) methodology for quantifying Pseudo‐nitzschia australis using ribosomal RNA‐targeted probes in sandwich and fluorescent in situ hybridization formats

Greenfield, D. I., Marin, R., Jensen, S. D., Massion, E., Roman, B., Feldman, J., & Scholin, C. A. (2006) · Limnology and Oceanography Methods · doi:10.4319/lom.2006.4.426 · Cited by 89

Resolving the complex relationship between harmful algal blooms and environmental factors in the coastal waters adjacent to the Changjiang River estuary

Zhou, Z., Yu, R., & Zhou, M. (2017) · Harmful Algae · doi:10.1016/j.hal.2016.12.006 · Cited by 86

Sources, factors, mechanisms and possible solutions to pollutants in marine ecosystems

Mostofa, K. M. G., Liu, C., Vione, D. V., Gao, K., & Ogawa, H. (2013) · Environmental Pollution · doi:10.1016/j.envpol.2013.08.005 · Cited by 66

Point-of-care diagnostics, a major opportunity for change in traditional diagnostic approaches: potential and limitations

McPartlin, D. A., & O’Kennedy, R. J. (2014) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.2014.960516 · Cited by 58

Scales characterising a high density thin layer of Dinophysis acuta Ehrenberg and its transport within a coastal jet

Farrell, H., Gentien, P., Fernand, L., Lunven, M., Reguera, B., González-Gil, S., & Raine, R. (2011) · Harmful Algae · doi:10.1016/j.hal.2011.11.003 · Cited by 58

Harmful algal blooms and eutrophication along the mexican coast of the Gulf of Mexico large marine ecosystem

Ulloa, M. J., Alvarez‐Torres, P., Horak-Romo, K. P., & Ortega-Izaguirre, R. (2016) · Environmental Development · doi:10.1016/j.envdev.2016.10.007 · Cited by 57

Highly sensitive detection of multiple tumor markers for lung cancer using gold nanoparticle probes and microarrays

Gao, W., Wang, W., Yao, S., Wu, S., Zhang, H., Zhang, J., Jing, F., Mao, H., Jin, Q., Cong, H., et al. (2016) · Analytica Chimica Acta · doi:10.1016/j.aca.2016.12.016 · Cited by 57

Simultaneous monitoring of faecal indicators and harmful algae using an in-situ autonomous sensor

Yamahara, K. M., Demir‐Hilton, E., Preston, C., Marin, R., Pargett, D. M., Roman, B., Jensen, S., Birch, J. M., Boehm, A. B. B., & Scholin, C. A. (2015) · Letters in Applied Microbiology · doi:10.1111/lam.12432 · Cited by 54

Variability of paralytic shellfish toxin occurrence and profiles in bivalve molluscs from Great Britain from official control monitoring as determined by pre-column oxidation liquid chromatography and implications for applying immunochemical tests

Turner, A. D., Stubbs, B., Coates, L., Dhanji‐Rapkova, M., Hatfield, R. G., Lewis, A. M., Rowland-Pilgrim, S. J., O’Neil, A., Stubbs, P., Ross, S. H., et al. (2013) · Harmful Algae · doi:10.1016/j.hal.2013.10.014 · Cited by 53

Harmful algal bloom forecast system for SW Ireland. Part II: Are operational oceanographic models useful in a HAB warning system

Cusack, C. K., Dabrowski, T., Lyons, K., Berry, A., Westbrook, G., Salas, R., Duffy, C. M. C., Nolan, G. D., & Silke, J. (2016) · Harmful Algae · doi:10.1016/j.hal.2015.11.013 · Cited by 47

Application of passive (SPATT) and active sampling methods in the profiling and monitoring of marine biotoxins

McCarthy, M., van Pelt, F. N. A. M., Bane, V., O’Halloran, J., & Furey, A. (2014) · Toxicon · doi:10.1016/j.toxicon.2014.07.005 · Cited by 46

Advances in Microfluidics and Lab-on-a-Chip Technologies

Jayamohan, H., Romanov, V., Li, H., Son, J., Samuel, R., Nelson, J., & Gale, B. K. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802971-8.00011-0 · Cited by 46

Seasonality in the excystment of Alexandrium minutum and Alexandrium tamarense in Irish coastal waters

Rathaille, A. N., & Raine, R. (2011) · Harmful Algae · doi:10.1016/j.hal.2011.04.015 · Cited by 44

Effect of environmental and nutritional factors on growth and azaspiracid production of the dinoflagellate Azadinium spinosum

Jauffrais, T., Séchet, V., Herrenknecht, C., Truquet, P., Savar, V., Tillmann, U., & Heß, P. (2013) · Harmful Algae · doi:10.1016/j.hal.2013.05.009 · Cited by 37

The ALGADEC device: A semi-automated rRNA biosensor for the detection of toxic algae

Diercks‐Horn, S., Metfies, K., Jäckel, S., & Medlin, L. K. (2011) · Harmful Algae · doi:10.1016/j.hal.2011.02.001 · Cited by 36

Probing the living ocean with ecogenomic sensors

Ottesen, E. A. (2016) · Current Opinion in Microbiology · doi:10.1016/j.mib.2016.03.012 · Cited by 33

Harmful algal bloom forecast system for SW Ireland. Part I: Description and validation of an operational forecasting model

Dabrowski, T., Lyons, K., Nolan, G. D., Berry, A., Cusack, C. K., & Silke, J. (2016) · Harmful Algae · doi:10.1016/j.hal.2015.11.015 · Cited by 33

Use of biosensors for the detection of marine toxins

McPartlin, D. A., Lochhead, M. J., Connell, L. B., Doucette, G. J., & O’Kennedy, R. J. (2016) · Essays in Biochemistry · doi:10.1042/ebc20150006 · Cited by 31

Monoclonal antibody against the surface of Alexandrium minutum used in a whole-cell ELISA

Gas, F., Pinto, L., Baus, B., Gaufres, L., Crassous, M.-P., Compère, C., & Quéméneur, É. (2008) · Harmful Algae · doi:10.1016/j.hal.2008.08.027 · Cited by 28

Electrochemical RNA genosensors for toxic algal species: enhancing selectivity and sensitivity

Orozco, J., Villa, E., Manes, C.-L. D. O., Medlin, L. K., & Guillebault, D. (2016) · Talanta · doi:10.1016/j.talanta.2016.08.073 · Cited by 28

Molecular probes and microarrays for the detection of toxic algae in the genera Dinophysis and Phalacroma (Dinophyta)

Edvardsen, B., Dittami, S. M., Groben, R., Brubak, S., Escalera, L., Rodríguez, F., Reguera, B., Chen, J., & Medlin, L. K. (2012) · Environmental Science and Pollution Research · doi:10.1007/s11356-012-1403-1 · Cited by 26

Rapid detection and quantification of the marine toxic algae, Alexandrium minutum, using a super-paramagnetic immunochromatographic strip test

Gas, F., Baus, B., Quéré, J., Chapelle, A., & Dréanno, C. (2015) · Talanta · doi:10.1016/j.talanta.2015.10.036 · Cited by 26

Monitoring a toxic bloom of Alexandrium minutum using novel microarray and multiplex surface plasmon resonance biosensor technology

McCoy, G. R., McNamee, S. E., Campbell, K., Elliott, C. T., Fleming, G. T. A., & Raine, R. (2014) · Harmful Algae · doi:10.1016/j.hal.2013.12.003 · Cited by 23

Biosensor-Based Technologies for the Detection of Pathogens and Toxins

Moran, K., Fitzgerald, J., McPartlin, D. A., Loftus, J. H., & O’Kennedy, R. J. (2016) · Comprehensive analytical chemistry · doi:10.1016/bs.coac.2016.04.002 · Cited by 23

Microarray testing for the presence of toxic algae monitoring programme in Galicia (NW Spain)

Dittami, S. M., Pazos, Y., Laspra, M., & Medlin, L. K. (2013) · Environmental Science and Pollution Research · doi:10.1007/s11356-012-1295-0 · Cited by 21

Application of reverse dot blot hybridization to simultaneous detection and identification of harmful algae

Chen, G. F., Zhang, C. Y., Wang, Y. Y., & Chen, W. (2015) · Environmental Science and Pollution Research · doi:10.1007/s11356-015-4141-3 · Cited by 14

Interannual variability in the timing of New England shellfish toxicity and relationships to environmental forcing

Nair, A., Thomas, A. C., & Borsuk, M. E. (2013) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2013.01.023 · Cited by 12

Improved DNA microarray detection sensitivity through immobilization of preformed in solution streptavidin/biotinylated oligonucleotide conjugates

Mavrogiannopoulou, E., Petrou, P. S., Koukouvinos, G., Yannoukakos, D., Siafaka‐Kapadai, A., Fornal, K., Awsiuk, K., Budkowski, A., & Kakabakos, S. E. (2015) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2015.02.045 · Cited by 11

A retrospective appraisal of the importance of high-resolution sampling for harmful algal blooms: Lessons from long-term phytoplankton monitoring at Sherkin Island, S.W. Ireland

Dale, B., & Murphy, M. (2014) · Harmful Algae · doi:10.1016/j.hal.2014.09.007 · Cited by 11

Evolution of the MIDTAL microarray: the adaption and testing of oligonucleotide 18S and 28S rDNA probes and evaluation of subsequent microarray generations with Prymnesium spp. cultures and field samples

McCoy, G. R., Touzet, N., Fleming, G. T. A., & Raine, R. (2015) · Environmental Science and Pollution Research · doi:10.1007/s11356-015-4152-0 · Cited by 8

Environmental links to interannual variability in shellfish toxicity in Cobscook Bay and eastern Maine, a strongly tidally mixed coastal region

Horecka, H. M., Thomas, A. C., & Weatherbee, R. A. (2013) · Deep Sea Research Part II Topical Studies in Oceanography · doi:10.1016/j.dsr2.2013.01.013 · Cited by 3

Future HAB science: Directions and challenges in a changing climate

Wells, M. L., Karlson, B., Wulff, A., Kudela, R. M., Trick, C. G., Asnaghi, V., Berdalet, E., Cochlan, W. P., Davidson, K., Rijcke, M. D., et al. (2019) · Harmful Algae · doi:10.1016/j.hal.2019.101632 · Cited by 491

Recent Progress in Biosensors for Environmental Monitoring: A Review

Justino, C. I. L., Duarte, A. C., & Rocha‐Santos, T. (2017) · Sensors · doi:10.3390/s17122918 · Cited by 457

Harmful Algal Blooms in Eutrophic Marine Environments: Causes, Monitoring, and Treatment

Lan, J., Liu, P., Hu, X., & Zhu, S. (2024) · Water · doi:10.3390/w16172525 · Cited by 246

Improved Prediction of Harmful Algal Blooms in Four Major South Korea’s Rivers Using Deep Learning Models

Lee, S. M., & Lee, D.-H. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15071322 · Cited by 215

Harmful algal blooms under changing climate and constantly increasing anthropogenic actions: the review of management implications

Nwankwegu, A. S., Li, Y., Huang, Y., Wei, J., Norgbey, E., Sarpong, L., Lai, Q., & Wang, K. (2019) · 3 Biotech · doi:10.1007/s13205-019-1976-1 · Cited by 121

Optical assessment of harmful algal blooms (HABs)

Busch, J. A., Zielinski, O., & Cembella, A. D. (2013) · Elsevier eBooks · doi:10.1533/9780857093523.2.171 · Cited by 4

Use of biosensors for the detection of marine toxins

McPartlin, D. A., Lochhead, M. J., Connell, L. B., Doucette, G. J., & O’Kennedy, R. J. (2016) · Essays in Biochemistry · doi:10.1042/ebc20150006 · Cited by 31

Development of low cost device for in-situ algae monitoring

Bradley, A. J., Caruso, W. C., Zheng, Y., Thangaraj, C., & McPheron, B. D. (2016) · IEEE MIT Undergraduate Research Technology Conference (URTC) · doi:10.1109/urtc.2016.8284076 · Cited by 3

Harmful Microalgae Detection: Biosensors versus Some Conventional Methods

Chin, J. J. C. C., Rahman, M., Ibrahim, N., Heng, L. Y., Tan, L. L., & Ahmad, A. (2022) · Sensors · doi:10.3390/s22093144 · Cited by 45

Advances in Harmful Algal Blooms (HABs) Monitoring: A Review of Sensor and Platform Technologies

Yang, Z., Tao, A., & Wang, G. (2026) · Journal of Marine Science and Engineering · doi:10.3390/jmse14100946 · Cited by 1