The multifaceted role of Nrf2 in mitochondrial function
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Items 101–200 of 368
- Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathwaysManon Lernoux, Michaël Schnekenburger, Mario A. Dicato, Marc F. Diederich · 2017 · Pharmacological Research
- Mitochondrial protective effect of neferine through the modulation of nuclear factor erythroid 2‐related factor 2 signalling in ischaemic strokeChuanhong Wu, Jianxin Chen, Ruocong Yang, Feipeng Duan, Shaojing Li, Xiuping Chen · 2018 · British Journal of Pharmacology
- Nrf2/Wnt resilience orchestrates rejuvenation of glia-neuron dialogue in Parkinson's diseaseBianca Marchetti · 2020 · Redox Biology
- NF‐E2‐related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin‐1 mutated Alzheimer's disease astrocytesMinna Oksanen, Ida Hyötyläinen, Kalevi Trontti, Taisia Rõlova, Sara Wojciechowski, Marja Koskuvi, Matti H. Viitanen, Anna–Liisa Levonen, Iiris Hovatta, Laurent Roybon et al. · 2019 · Glia
- Caniferolide A, a Macrolide from Streptomyces caniferus, Attenuates Neuroinflammation, Oxidative Stress, Amyloid-Beta, and Tau Pathology in VitroRebeca Alvariño, Eva Alonso, Rodney Lacret, Daniel Oves‐Costales, Olga Genilloud, Fernando Reyes, Amparo Alfonso, Luis Miguel Botana · 2019 · Molecular Pharmaceutics
- Nrf2 deficiency aggravates PM2.5-induced cardiomyopathy by enhancing oxidative stress, fibrosis and inflammation via RIPK3-regulated mitochondrial disorderChenxu Ge, Linfeng Hu, Deshuai Lou, Qiang Li, Jing Feng, Yekuan Wu, Jun Tan, Minxuan Xu · 2020 · Aging
- Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorderAlessandra Pecorelli, Francesca Ferrara, Nicolò Messano, Valeria Cordone, Maria Lucia Schiavone, Franco Cervellati, Brittany L. Woodby, Carlo Cervellati, Joussef Hayek, Giuseppe Valacchi · 2020 · The FASEB Journal
- The implication of mitochondrial dysfunction and mitochondrial oxidative damage in di (2-ethylhexyl) phthalate induced nephrotoxicity in both in vivo and in vitro modelsSorour Ashari, Mohammad Yasin Karami, Mohammad Shokrzadeh, Morteza Ghandadi, Nasrin Ghassemi-Barghi, Ayat Dashti, Mohammad Ranaee, Hamidreza Mohammadi · 2020 · Toxicology Mechanisms and Methods
- Mitochondrial dysfunction in cognitive neurodevelopmental disorders: Cause or effect?Ayyappan Anitha, Ismail Thanseem, Mary Iype, Sanjeev V. Thomas · 2023 · Mitochondrion
- Omaveloxolone: an activator of Nrf2 for the treatment of Friedreich ataxiaVictoria Profeta, Kellie McIntyre, McKenzie Wells, Courtney C. Park, David R. Lynch · 2023 · Expert Opinion on Investigational Drugs
- Sulforaphane Promotes Mitochondrial Protection in SH-SY5Y Cells Exposed to Hydrogen Peroxide by an Nrf2-Dependent MechanismMarcos Roberto de Oliveira, Flávia Bittencourt Brasil, Cristina Ribas Fürstenau · 2017 · Molecular Neurobiology
- Neuron-based high-content assay and screen for CNS active mitotherapeuticsBoglárka H. Várkuti, Miklós Képiró, Ze Liu, Kyle A. Vick, Yosef Avchalumov, Rodrigo Pacifico, Courtney MacMullen, Theodore M. Kamenecka, Sathyanarayanan V. Puthanveettil, Ronald L. Davis · 2020 · Science Advances
- H2O2-preconditioned human adipose-derived stem cells (HC016) increase their resistance to oxidative stress by overexpressing Nrf2 and bioenergetic adaptationPatricia Garrido, Ana Alonso‐Varona, Begoña Castro, María Burón, Teodoro Palomares · 2020 · Stem Cell Research & Therapy
- Role of Mitochondrial Dysfunctions in Neurodegenerative Disorders: Advances in Mitochondrial BiologyDivya Sri Kathiresan, Rubadevi Balasubramani, Kamalesh Marudhachalam, Piyush Jaiswal, Nivedha Ramesh, Gunna Sureshbabu Suruthi, Puthamohan Vinayaga Moorthi, Murali Vijayan · 2024 · Molecular Neurobiology
- Carnosic Acid as a Promising Agent in Protecting Mitochondria of Brain CellsMarcos Roberto de Oliveira · 2018 · Molecular Neurobiology
- The NRF2 Signaling Network Defines Clinical Biomarkers and Therapeutic Opportunity in Friedreich’s AtaxiaPiergiorgio La Rosa, Enrico Bertini, Fiorella Piemonte · 2020 · International Journal of Molecular Sciences
- The interplay between oxidative stress and bioenergetic failure in neuropsychiatric illnesses: can we explain it and can we treat it?Gerwyn Morris, Ken R. Walder, M. Berk, Wolfgang Marx, Adam J. Walker, Michael H. J. Maes, Basant K. Puri · 2020 · Molecular Biology Reports
- Co-signaling receptors regulate T-cell plasticity and immune toleranceHaitao Shen · 2018 · Frontiers in bioscience
- Omega-3 Fatty Acids Upregulate SIRT1/3, Activate PGC-1α via Deacetylation, and Induce Nrf1 Production in 5/6 Nephrectomy Rat ModelSung Hyun Son, Su Mi Lee, Mihwa Lee, Young Ki Son, Seong Eun Kim, Won Suk An · 2021 · Marine Drugs
- Progress in the treatment of Friedreich ataxiaGeneieve Tai, Louise A. Corben, Eppie Mildred Yiu, Sarah Milne, Martin Bruce Delatycki · 2018 · Neurologia i Neurochirurgia Polska
- Nrf2, cellular redox regulation, and neurologic implicationsEduardo Elias Benarroch · 2017 · Neurology
- PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer’s diseaseXiaojuan Wang, Lin Qi, Ya-Fang Cheng, Xuefei Ji, Tianyan Chi, Peng Liu, Libo Zou · 2021 · Acta Pharmacologica Sinica
- miR‑155 modulates high glucose‑induced cardiac fibrosis via the Nrf2/HO‑1 signaling pathwayYu Li, Jing‑Zhu Duan, Qian He, Chong‐Quan Wang · 2020 · Molecular Medicine Reports
- TGR5 Agonist INT-777 Alleviates Inflammatory Neurodegeneration in Parkinson’s Disease Mouse Model by Modulating Mitochondrial Dynamics in MicrogliaRui Huang, Yuyuan Gao, Jianing Chen, Qingrui Duan, Peikun He, Jiahui Zhang, Heling Huang, Qingxi Zhang, Guixian Ma, Yuhu Zhang et al. · 2022 · Neuroscience
- Mitochondrial mechanisms in Cerebral Ischemia-Reperfusion Injury: Unravelling the intricaciesShiv Kumar Saini, Damanpreet Singh · 2024 · Mitochondrion
- NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell DifferentiationChiara De Nuccio, Antonietta Bernardo, Carmen Troiano, Maria Stefania Brignone, Mario Falchi, Anita Greco, Michela Rosini, Filippo Basagni, Cristina Lanni, Melania Maria Serafini et al. · 2020 · International Journal of Molecular Sciences
- Circadian control of p75 neurotrophin receptor leads to alternate activation of Nrf2 and c-Rel to reset energy metabolism in astrocytes via brain-derived neurotrophic factorTetsuro Ishii, Eiji Warabi, Giovanni E. Mann · 2018 · Free Radical Biology and Medicine
- Induced Ketosis as a Treatment for Neuroprogressive Disorders: Food for Thought?Gerwyn Morris, Basant K. Puri, Andre Ferrer Carvalho, Michael H. J. Maes, Michael Berk, Anu A. Ruusunen, LISA S. OLIVE · 2020 · The International Journal of Neuropsychopharmacology
- Unlocking the Mystery of the Therapeutic Effects of Chinese Medicine on CancerShao-Hsiang Liu, P. Chen, Chun-Chieh Huang, Yi-Tu Hung, Mei-Ying Lee, Wei-Hung Lin, Yuan-Chuan Lin, A. Lee · 2021 · Frontiers in Pharmacology
- Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular basis to therapyMaria Concetta Scuto, Sergio Modafferi, Francesco Rampulla, Vincenzo Zimbone, Mario Tomasello, Sestina Maria Spanò, Maria Laura Ontario, Agostino Palmeri, Angela Trovato Salinaro, Rosalba Siracusa et al. · 2022 · Mechanisms of Ageing and Development
- Anticancer Effects of Thymoquinone through the Antioxidant Activity, Upregulation of Nrf2, and Downregulation of PD-L1 in Triple-Negative Breast Cancer CellsGetinet Mequanint Adinew, Samia S. Messeha, Equar Taka, Ramesh Babu Badisa, Karam F. A. Soliman · 2022 · Nutrients
- The Interplay of Protein Aggregation, Genetics, and Oxidative Stress in Alzheimer’s Disease: Role for Natural Antioxidants and ImmunotherapeuticsJawad Ali, Kyonghwan Choe, Jun Sung Park, Hyun Young Park, Heeyoung Kang, Tae Ju Park, Myeong-Ok Kim · 2024 · Antioxidants
- Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncouplingVerena Coleman, Piangkwan Sa‐nguanmoo, Jeannette Koenig, Tim J. Schulz, Tilman Grune, Susanne Klaus, Anna Patricia Kipp, Mario Ost · 2018 · Scientific Reports
- Chronic mild Hyperhomocysteinemia impairs energy metabolism, promotes DNA damage and induces a Nrf2 response to oxidative stress in rats brainTiago Marcon dos Santos, Cassiana Siebert, Micaela Federizzi de Oliveira, Vanusa Manfredini, Ângela Terezinha de Souza Wyse · 2019 · Cellular and Molecular Neurobiology
- New developments in pharmacotherapy for Friedreich ataxiaAlexandra Clay, Patrick Hearle, Kimberly A. Schadt, David R. Lynch · 2019 · Expert Opinion on Pharmacotherapy
- The activation of nuclear factor-E2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling blunts cholestasis-induced liver and kidney injuryKhadijeh Mousavi, Hossein Niknahad, Huifeng Li, Zhipeng Jia, Ram Kumar Manthari, Yangfei Zhao, Xiong Shi, Yuanyu Chen, Asrin Ahmadi, Negar Azarpira et al. · 2021 · Toxicology Research
- Trehalose inhibits H2O2-induced autophagic death in dopaminergic SH-SY5Y cells via mitigation of ROS-dependent endoplasmic reticulum stress and AMPK activationZhijie Gao, Helei Wang, Bo Zhang, Xuemei Wu, Yanfeng Zhang, Pengfei Ge, Guangfan Chi, Jianmin Liang · 2018 · International Journal of Medical Sciences
- Anthocyanin Extract from Purple Sweet Potato Exacerbate Mitophagy to Ameliorate Pyroptosis in Klebsiella pneumoniae InfectionGuokai Dong, Nana Xu, Meng Wang, Yunyun Zhao, Fei Jiang, Huimin Bu, Jinjuan Liu, Bo Yuan, Rongpeng Li · 2021 · International Journal of Molecular Sciences
- Homocysteine and Parkinson's diseaseLingyan Zhou · 2023 · CNS Neuroscience & Therapeutics
- Ilexgenin A inhibits mitochondrial fission and promote Drp1 degradation by Nrf2‐induced PSMB5 in endothelial cellsYingchao Zhu, Ming Li, Ya‐Wen Lu, Jun Li, Ke Ye, Jie Yang · 2019 · Drug Development Research
- Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney diseaseXia Gu, Yi Liu, Na Wang, Junhui Zhen, Bo Zhang, Shaoshuai Hou, Zheng‐Guo Cui, Qiang Wan, Hong Feng · 2021 · Free Radical Biology and Medicine
- Nrf2: A unifying transcription factor in the pathogenesis of Fuchs’ endothelial corneal dystrophyMatthew Lovatt, Viridiana Kocaba, Dawn Jing Hui Neo, Yu Qiang Soh, Jodhbir Singh Mehta · 2020 · Redox Biology
- MitoQ protects against high glucose-induced brain microvascular endothelial cells injury via the Nrf2/HO-1 pathwayMin-yan Yang, Zhen Fan, Zhao Zhang, Jin Fan · 2020 · Journal of Pharmacological Sciences
- An NRF2 Perspective on Stem Cells and AgeingMatthew B. Dodson, Annadurai Anandhan, Donna D. Zhang, Lalitha Madhavan · 2021 · Frontiers in Aging
- Recurrent Human Papillomavirus–Related Head and Neck Cancer Undergoes Metabolic Reprogramming and Is Driven by Oxidative PhosphorylationAvani Vyas, R. Alex Harbison, Daniel L. Faden, Mark Kubik, Drake Palmer, Qing Zhang, Hatice U. Osmanbeyoglu, Kirill I. Kiselyov, Eduardo Méndez, Umamaheswar Duvvuri · 2021 · Clinical Cancer Research
- Pattern of Mitochondrial Respiration in Peripheral Blood Cells of Patients with Parkinson’s DiseaseTommaso Schirinzi, Illari Salvatori, Henri Zenuni, Piergiorgio Grillo, Cristiana Valle, Giuseppina Martella, Nicola Biagio Mercuri, Alberto Ferri · 2022 · International Journal of Molecular Sciences
- Immunometabolic reprogramming of macrophages by gut microbiota-derived cadaverine controls colon inflammationRodrigo de Oliveira Formiga, Qing Li, Yining Zhao, Márcio A. C. Ribeiro, Perle Guarino-Vignon, Rand Fatouh, Léonard Dubois, Laura Creusot, Virginie Puchois, Salomé Amouyal et al. · 2025 · Cell Host & Microbe
- Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophagesSheyda Bahiraii, Martin Brenner, Fangfang Yan, Wolfram Weckwerth, Elke H. Heiß · 2022 · Frontiers in Immunology
- The Antinociceptive Role of Nrf2 in Neuropathic Pain: From Mechanisms to Clinical PerspectivesKęstutis Petrikonis, Jurga Bernatonienė, Dalia M. Kopustinskienė, Roberto Casale, Sergio Davinelli, Luciano Saso · 2024 · Pharmaceutics
- Promotion of mitochondrial protection by naringenin in methylglyoxal-treated SH-SY5Y cells: Involvement of the Nrf2/GSH axisMarcos Roberto de Oliveira, Izabel Cristina Custódio de Souza, Cristina Ribas Fürstenau · 2019 · Chemico-Biological Interactions
- The Nrf2 pathway in psychiatric disorders: pathophysiological role and potential targetingRanjana Bhandari, Japneet Kaur, Simerpreet Kaur, Anurag Kuhad · 2021 · Expert Opinion on Therapeutic Targets
- The compensatory antioxidant response system with a focus on neuroprogressive disordersGerwyn Morris, Basant K. Puri, Adam J. Walker, Michael Berk, Ken R. Walder, Chiara C. Bortolasci, Wolfgang Marx, Andre Ferrer Carvalho, Michael H. J. Maes · 2019 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Protective Effect of Sulforaphane on Oxidative Stress and Mitochondrial Dysfunction Associated with Status Epilepticus in Immature RatsJaroslava Folbergrová, Pavel Ješina, Jakub Otáhal · 2023 · Molecular Neurobiology
- From Microcirculation to Aging-Related Diseases: A Focus on Endothelial SIRT1Martin Law, Peichun Wang, Zhong-Yan Zhou, Yu Wang · 2024 · Pharmaceuticals
- Mitochondria-Targeted Hydrogen Sulfide Delivery Molecules Protect Against UVA-Induced Photoaging in Human Dermal Fibroblasts, and in Mouse Skin In VivoJinapath Lohakul, Saowanee Jeayeng, Anyamanee Chaiprasongsuk, Roberta Torregrossa, Mark E. Wood, Malinee Saelim, Weerawon Thangboonjit, Matthew Whiteman, Uraiwan Panich · 2021 · Antioxidants and Redox Signaling
- Crosstalk between mitochondrial metabolism and oxidoreductive homeostasis: a new perspective for understanding the effects of bioactive dietary compoundsMariangela Di Giacomo, Vincenzo Zara, Paolo Bergamo, Alessandra Ferramosca · 2019 · Nutrition Research Reviews
- Alternative NADH dehydrogenase extends lifespan and increases resistance to xenobiotics in DrosophilaDmytro V. Gospodaryov, O. Strilbytska, U. Semaniuk, Natalia V. Perkhulyn, B. Rovenko, Ihor Yurkevych, Ana G. Barata, T. Dick, O. Lushchak, H. Jacobs · 2019 · Biogerontology (Dordrecht)
- NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytesXinyuan Zhang, Ye Liang, Hao Xu, Qin Zhou, Bin Tan, Qin Yi, Yan Liang, Min Xie, Yin Zhang, Jie Tian et al. · 2021 · Stem Cell Research & Therapy
- Pathogenic Mechanisms of Myeloma Bone Disease and Possible Roles for NRF2Chia‐Hung Yen, Chin‐Mu Hsu, Samuel Yien Hsiao, Hui‐Hua Hsiao · 2020 · International Journal of Molecular Sciences
- Mechanisms underlying the hormetic effect of conjugated linoleic acid: Focus on Nrf2, mitochondria and NADPH oxidasesDi Cristofano M, Alessandra Ferramosca, Mariangela Di Giacomo, Carmela Fusco, Floriana Boscaino, Diomira Luongo, Vera Rotondi Aufiero, Francesco Maurano, Ennio Cocca, Giuseppe Mazzarella et al. · 2021 · Free Radical Biology and Medicine
- Targeting the Metabolic Paradigms in Cancer and DiabetesMira Bosso, Dania Haddad, Ashraf Said Al Madhoun, Fahd Al‐Mulla · 2024 · Biomedicines
- CRISPR/Cas9 Editing of Glia Maturation Factor Regulates Mitochondrial Dynamics by Attenuation of the NRF2/HO-1 Dependent Ferritin Activation in Glial CellsGovindhasamy Pushpavathi Selvakumar, Mohammad Ejaz Ahmed, Sudhanshu P. Raikwar, Ramasamy Thangavel, Duraisamy Kempuraj, Iuliia Dubova, Daniyal Saeed, Haris Zahoor, Keerthivaas Premkumar, Smita A. Zaheer et al. · 2019 · Journal of Neuroimmune Pharmacology
- Isoorientin exerts a protective effect against 6-OHDA-induced neurotoxicity by activating the AMPK/AKT/Nrf2 signalling pathwayLi Ma, Boxi Zhang, Jiahe Liu, Chunyu Qiao, Yuanyuan Liu, Shize Li, Hongming Lv · 2020 · Food & Function
- Synthetic Control of Mitochondrial Dynamics: Developing Three-Coordinate Au(I) Probes for Perturbation of Mitochondria Structure and FunctionRandall Tyler Mertens, William C. Jennings, Samuel Ofori, Jong Hyun Kim, Sean Parkin, Gunnar F. Kwakye, Samuel G. Awuah · 2021 · JACS Au
- Activation of the Nrf2/ARE signaling pathway protects against palmitic acid-induced renal tubular epithelial cell injury by ameliorating mitochondrial reactive oxygen species-mediated mitochondrial dysfunctionXu-shun Jiang, Meng-yao Cai, Xunjia Li, Qing Peter Wild Zhong, Man-li Li, Yunfeng Xia, Qing Xiang Shen, Xiaogang Du, Hua Gan · 2022 · Frontiers in Medicine
- Reactive Oxygen Species-Mediated Autophagy Defines the Fate of Cancer Stem CellsMatilde Esther LLeonart, Etna Abad, Dmitry Graifer, Alex Lyakhovich · 2017 · Antioxidants and Redox Signaling
- Gastrodin alleviates glucocorticoid induced osteoporosis in rats via activating the Nrf2 signaling pathwaysShengye Liu, Long Zhou, Liyu Yang, Shuai Mu, Tao Fang, Qin Fu · 2018 · Oncotarget
- Antioxidant and Hepatoprotective Effects of Croton hypoleucus Extract in an Induced-Necrosis Model in RatsThania Alejandra Urrutia-Hernández, Jorge Arturo Santos-López, Juana Benedı́, Francisco José Sánchez-Muniz, Claudia Velázquez, Minarda De la O‐Arciniega, Osmar Antonio Jaramillo‐Morales, Mirandeli Bautista · 2019 · Molecules
- Orosomucoid 1 Attenuates Doxorubicin‐Induced Oxidative Stress and Apoptosis in Cardiomyocytes via Nrf2 SignalingXiaoli Cheng, Dan Liu, Ruinan Xing, Haixu Song, Xiaoxiang Tian, Chenghui Yan, Yaling Han · 2020 · BioMed Research International
- Pachymic Acid Ameliorates Pulmonary Hypertension by Regulating Nrf2-Keap1-ARE PathwayYuan Zhang He, Jian-hua Zhong, Xiaodong Wei, Chuying Huang, Pailan Peng, Jun Yao, Xiusheng Song, Wan-li Fan, Guang‐Cai Li · 2021 · Current Medical Science
- The Development of Dyslipidemia in Chronic Kidney Disease and Associated Cardiovascular Damage, and the Protective Effects of CurcuminoidsZeltzin Alejandra Ceja-Galicia, Ana Karina Aranda‐Rivera, Isabel Amador‐Martínez, Omar Emiliano Aparicio‐Trejo, Edilia Tapia, Joyce Trujillo, Victoria Ramírez, José Pedraza‐Chaverrí · 2023 · Foods
- Inhibition of the Nrf2/HO-1 Axis Suppresses the Mitochondria-Related Protection Promoted by Gastrodin in Human Neuroblastoma Cells Exposed to ParaquatMarcos Roberto de Oliveira, Flávia Bittencourt Brasil, Cristina Ribas Fürstenau · 2018 · Molecular Neurobiology
- Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD modelsWing Hei Au, Leonor Miller‐Fleming, Álvaro Sánchez-Martínez, James Lee, Madeleine J. Twyning, Hiran A. Prag, Laura Raik, Scott P. Allen, Pamela J. Shaw, Laura Ferraiuolo et al. · 2024 · Life Science Alliance
- Cytoprotective Effects of Punicalagin on Hydrogen–Peroxide–Mediated Oxidative Stress and Mitochondrial Dysfunction in Retinal Pigment Epithelium CellsMaria Elisabetta Clementi, Giuseppe Maulucci, Giada Bianchetti, Michela Pizzoferrato, Beatrice Sampaolese, Giuseppe Tringali · 2021 · Antioxidants
- Sulforaphane and Brain Health: From Pathways of Action to Effects on Specific DisordersJed W. Fahey, Hua Liu, Holly Batt, Anita A. Panjwani, Petra Akiko Tsuji · 2025 · Nutrients
- Sestrins: Darkhorse in the regulation of mitochondrial health and metabolismAshish A. Kumar, Deepshikha Dhiman, Chandrima Shaha · 2020 · Molecular Biology Reports
- Enhanced NRF2 expression mitigates the decline in neural stem cell function during agingAnnadurai Anandhan, Konner R. Kirwan, Mandi J. Corenblum, Lalitha Madhavan · 2021 · Aging Cell
- NRF2 in Cancer: Cross-Talk with Oncogenic Pathways and Involvement in Gammaherpesvirus-Driven CarcinogenesisMara Cirone, Gabriella D’Orazi · 2022 · International Journal of Molecular Sciences
- Promoting a pro-oxidant state in skeletal muscle: Potential dietary, environmental, and exercise interventions for enhancing endurance-training adaptationsAdam Jordan, Christopher G. R. Perry, Arthur J. Cheng · 2021 · Free Radical Biology and Medicine
- Omaveloxolone and TX63682 are hepatoprotective in the STAM mouse model of nonalcoholic steatohepatitisScott A. Reisman, Deborah A. Ferguson, Chun‐Yue I. Lee, Joel W. Proksch · 2020 · Journal of Biochemical and Molecular Toxicology
- Pinocembrin pretreatment counteracts the chlorpyrifos-induced HO-1 downregulation, mitochondrial dysfunction, and inflammation in the SH-SY5Y cellsFlávia Bittencourt Brasil, Fhelipe Jolner Souza de Almeida, Matheus Dargesso Luckachaki, Evandro Luiz Dall’Oglio, Marcos Roberto de Oliveira · 2021 · Metabolic Brain Disease
- “Reframing” dopamine signaling at the intersection of glial networks in the aged Parkinsonian brain as innate Nrf2/Wnt driver: Therapeutical implicationsBianca Marchetti, Carmela Giachino, Cataldo Tirolo, Maria Francesca Serapide · 2022 · Aging Cell
- Genome-wide identification and analysis of Nrf2 binding sites – Antioxidant response elements in zebrafishAzhwar Raghunath, Nagarajan Raju, Kiruthika Sundarraj, Lakshmikanthan Panneerselvam, Ekambaram Perumal · 2018 · Toxicology and Applied Pharmacology
- Constitutive Activation of NAD-Dependent Sirtuin 3 Plays an Important Role in Tumorigenesis of Chromium(VI)-Transformed CellsMarco Clementino, Donghern Kim, Zhuo Zhang · 2019 · Toxicological Sciences
- Peripheral Blood NRF2 Expression as a Biomarker in Human Health and DiseaseLee E. Neilson, Joseph F. Quinn, Nora E. Gray · 2020 · Antioxidants
- Nrf2 mitigates sepsis-associated encephalopathy-induced hippocampus ferroptosis via modulating mitochondrial dynamic homeostasisHaifeng Duan, Xin Yang, Shuhan Cai, Lei Zhang, Zebao Qiu, Jin Wang, Shun Wang, Zhi Li, Xinyi Li · 2024 · International Immunopharmacology
- Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodentsTiago Marcon dos Santos, Osmar Vieira Ramires Júnior, Vinícius Santos Alves, Robson Coutinho‐Silva, Luiz Eduardo Baggio Savio, Ângela Terezinha de Souza Wyse · 2021 · Life Sciences
- Nuclear factor erythroid 2-related factor 2 protects bovine mammary epithelial cells against free fatty acid-induced mitochondrial dysfunction in vitroYuanyuan Chen, Yan Jun Tang, Shengbin Luo, Hongdou Jia, Qiushi Xu, Renxu Chang, Zhihao Dong, Shuang Gao, Qian Song, Hao Dong et al. · 2021 · Journal of Dairy Science
- Clinical Research Progress of Small Molecule Compounds Targeting Nrf2 for Treating Inflammation-Related DiseasesZhenzhen Zhai, Yanxin Huang, Yawei Zhang, Lili Zhao, Wen Li · 2022 · Antioxidants
- NRF2 signaling in cytoprotection and metabolismShohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi · 2023
- Mutations in genes cnc or dKeap1 modulate stress resistance and metabolic processes in Drosophila melanogasterMaria M. Bayliak, Oleh Demianchuk, Dmytro V. Gospodaryov, Oleksandra Abrat, Maria P. Lylyk, Kenneth B. Storey, Volodymyr I. Lushchak · 2020 · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
- Interplay between nuclear factor erythroid 2-related factor 2 and inflammatory mediators in COVID-19-related liver injuryDandan Zhu, Xuemei Tan, Liqing Lu, Sijia Yu, Ru-Li Jian, Xinfang Liang, Yi-Xuan Liao, Wei Fan, Lucíia Barbier-Torres, Austin Yang et al. · 2021 · World Journal of Gastroenterology
- Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survivalChristopher Lowden, Aren Boulet, Nicholas A. Boehler, Shavanie Seecharran, Julian Rios Garcia, Nicholas J. Lowe, Jiashu Liu, Jonathan L.K. Ong, Wanzhang Wang, Lingfeng Ma et al. · 2021 · Cell Reports
- MnTE-2-PyP protects fibroblast mitochondria from hyperglycemia and radiation exposureArpita Chatterjee, Isin T. Sakallioglu, Divya Murthy, Elizabeth A. Kosmacek, Pankaj K. Singh, John Tyson McDonald, Robert Powers, Rebecca E. Oberley‐Deegan · 2022 · Redox Biology
- Cycloastragenol activation of telomerase improves β-Klotho protein level and attenuates age-related malfunctioning in ovarian tissuesMuhammad Idrees, Vikas Kumar, Abdul Majid Khan, Myeong‐Don Joo, Keun-Woo Lee, Sea Hwan Sohn, Il‐Keun Kong · 2022 · Mechanisms of Ageing and Development
- Neuro-modulatory impact of felodipine against experimentally-induced Parkinson's disease: Possible contribution of PINK1-Parkin mitophagy pathwayHadeer O. Abou-Hany, Mohamed El‐Sherbiny, Sally L. Elshaer, Eman Said, Tarek Moustafa · 2024 · Neuropharmacology
- Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 ExpressionJie Qi, Xiangyuan Chen, Qichao Wu, Jing Wang, Hao Zhang, Anrong Mao, Minmin Zhu, Changhong Miao · 2020 · Oxidative Medicine and Cellular Longevity
- Mitochondrial Protection and Anti-inflammatory Effects Induced by Emodin in the Human Neuroblastoma SH-SY5Y Cells Exposed to Hydrogen Peroxide: Involvement of the AMPK/Nrf2 Signaling PathwayMarcos Roberto de Oliveira, Izabel Cristina Custódio de Souza, Flávia Bittencourt Brasil · 2020 · Neurochemical Research
- Fine particulate matter exposure and perturbation of serum metabolome: A longitudinal study in Baoding, ChinaHuan Shu, Shuna Jin, Hongxiu Liu, Wei Xia, Gaodao Liang, Shunqing Xu, Xingjie Fang, Chunhui Li, Qianqian Wang, Xiaojie Sun et al. · 2021 · Chemosphere
- Novel Keap1-Nrf2 Protein-Protein Interaction Inhibitor UBE-1099 Ameliorates Progressive Phenotype in Alport Syndrome Mouse ModelShota Kaseda, Yuya Sannomiya, Jun Horizono, Jun Kuwazuru, Mary Ann Suico, Sayaka Ogi, Ryoko Sasaki, Hidetoshi Sunamoto, Hirohiko Fukiya, Hayato Nishiyama et al. · 2021 · Kidney360