Cited by 42Radiopharmaceutical Chemistry and ApplicationsMedical Imaging Techniques and ApplicationsArtificial Intelligence in Healthcare and Education

Role of Artificial Intelligence in Theranostics

Open access
Brosch-Lenz, Julia, Yousefirizi, Fereshteh, Zukotynski, Katherine, Beauregard, Jean-Mathieu, Gaudet, Vincent, Saboury, Babak, Rahmim, Arman, Uribe, Carlos·2021·PET Clinics

Abstract

We highlight emerging uses of artificial intelligence (AI) in the field of theranostics, focusing on its significant potential to enable routine and reliable personalization of radiopharmaceutical therapies (RPTs). Personalized RPTs require patient-specific dosimetry calculations accompanying therapy. Additionally we discuss the potential to exploit biological information from diagnostic and therapeutic molecular images to derive biomarkers for absorbed dose and outcome prediction; toward personalization of therapies. We try to motivate the nuclear medicine community to expand and align efforts into making routine and reliable personalization of RPTs a reality.

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Crossref · 10.1016/j.cpet.2021.06.002

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  • AI optimizes planning of radiopharmaceutical therapy by incorporating patient-specific factors, radiotracer biodistribution profiles, and dosimetry calculations.

    “AI’s role extends to optimizing the planning of radiopharmaceutical therapy, incorporating patient-specific factors, radiotracer biodistribution profiles, and dosimetry calculations [122].”

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References 113 · Cited by 42

Authors
Brosch-Lenz, J., Yousefirizi, F., Zukotynski, K., Beauregard, J.-M., Gaudet, V., Saboury, B., Rahmim, A., & Uribe, C.
Affiliations
  • BC Cancer Agency (CA)
  • McMaster University (CA)
  • Université Laval (CA)
  • University of Waterloo (CA)
  • National Institutes of Health (US)
Corresponding author
Uribe, Carlos
Venue
PET Clinics
Publisher
Elsevier BV
Published
2021-10
Volume
16
Issue
4
Pages
627-641
ISSN
1556-8598 (ISSN-L)
OpenAlex
W3199922519
Cited by
42
References
113
Citations by year
2026: 9 · 2025: 10 · 2024: 14 · 2023: 3 · 2022: 4 · 2021: 2
FWCI
0.94
Type
journal article
Language
en
Open access
Locations
  • PET Clinics (publishedVersion)
  • PubMed (publishedVersion)
  • UWSpace (University of Waterloo) (submittedVersion, cc-by-nc-nd)
Funders
Natural Sciences and Engineering Research Council of Canada (RGPIN-2019-06467, RGPIN-2021-02965)
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiopharmaceutical Chemistry and Applications
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
Keywords
artificial intelligence, theranostics, radiopharmaceutical therapy, personalized treatment, patient-specific dosimetry, outcome prediction, biomarkers, molecular imaging, nuclear medicine
MeSH terms
Artificial Intelligence, Humans, Nuclear Medicine, Radiometry, Radiopharmaceuticals, Precision Medicine

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