The clinical significance of loneliness: a literature review

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1. Prevalence of Loneliness and Associated Factors Among Iranian College Students During 2015
   Mehri Alaviani, Reza Parvan, Fattaneh Karimi, Saeid Safiri, Nader Mahdavi · 2017 · Journal of Archives in Military Medicine
2. Relationship of Deterministic Thinking With Loneliness and Depression in the Elderly
   Mehdi Sharifi, Dana Mohammad Aminzadeh, Erfan Soleimani Sefat, Nasrin Sudmand, Jalal Younesi · 2017 · Salmand
3. Formulating a model for the relationship between alexithymia, social support, loneliness, and marital satisfaction: Path analysis model
   Aliasghar Hoseinzadeh, MojganShariat Panahi, Mehdi Razaghpour, Nasrin Hosieni · 2018 · Journal of Family Medicine and Primary Care
4. The Perfect Storm: Mapping the Life Course Trajectories of Serial Killers
   Sasha Reid, Aleece Katan, Ayah Ellithy, Ran Della Stua, Egor V. Denisov · 2019 · International Journal of Offender Therapy and Comparative Criminology
5. Peer Victimization and Loneliness: The Moderating Role of School Connectedness by Gender.
   JoLynn V. Carney, Isak Kim, David Bright, Richard J. Hazler · 2020 · Journal of school counseling
6. Domestic violence and mental health in a Dutch community sample: The adverse role of loneliness
   Maarten Jacob Johannes Kunst, Stefan Bogaerts, Frans Willem Winkel · 2010 · Journal of Community & Applied Social Psychology
7. The Experience of Loneliness: Main and Interactive Effects of Interpersonal Stress, Social Support and Positive Affect
   Mette M. Aanes, Maurice B. Mittelmark, Jørn Hetland · 2009 · International Journal of Mental Health Promotion
8. Associations of Parental and Peer Rejection With Preadolescents’ Loneliness: Emotional Sensitivities as Mediators
   Samantha Ferguson, Melanie J. Zimmer‐Gembeck · 2014 · Journal of Relationships Research
9. Sex differences in loneliness, social isolation, and their impact on psychiatric symptoms and cognitive functioning in schizophrenia
   Jinghui Chi, Nannan Liu, Tian Tian, Qiaona Jiang, Chenghao Lu, Yanzhe Li, Xiaofei Zhang, Yanyan Ma, Lili Wang, Shen Li · 2024 · BMC Psychiatry
10. Social Processes Associated With Health and Health Behaviors Linked to Early Mortality in People With a Diagnosis of a Serious Mental Illness
    Karen L. Fortuna, Ashley Williams, George Mois, Kendra Jason, Cynthia L. Bianco · 2021 · Perspectives on Psychological Science
11. Loneliness Among the Elderly: a Mini Review
    Sandeep Grover · 2022 · Consortium Psychiatricum
12. Soledad y ansiedad durante el confinamiento por COVID-19. El efecto mediador de la regulación emocional
    Arturo Enrique Orozco Vargas · 2022 · Interdisciplinaria Revista de Psicología y Ciencias Afines
13. Understanding Loneliness in Brain Injury: Linking the Reaffiliation Motive Model of Loneliness With a Model of Executive Impairment
    Christopher Byrne, Christian E. Salas, Rudi Coetzer, Richard Ramsey · 2022 · Frontiers in Integrative Neuroscience
14. Profiles of interpersonal relationship qualities and trajectories of internalizing problems among Chinese adolescents
    Jianjie Xu, Ruixi Sun, Jingyi Shen, Yuchi Zhang, Wei Tong, Xiaoyi Fang · 2022 · Development and Psychopathology
15. Connected or Cutoff? A 4-Year Longitudinal Study of the Links Between Adolescents’ Compulsive Internet Use and Social Support
    James Nicholas Donald, Joseph Ciarrochi, Jiesi Guo · 2022 · Personality and Social Psychology Bulletin
16. Community-Based Providers’ Perspectives on Addressing Loneliness and Mental Health Services for Migrant Youth and Emerging Adults
    Melissa L. Bessaha, Ushana Persaud, Rukhsar Asfe, Miguel Muñoz‐Laboy · 2023 · Journal of Social Service Research
17. The 100 Top-Cited Studies on Loneliness: A Bibliometric Analysis
    Aditya Banerjee, Sarabjeet Kaur Chawla, Neena Kohli · 2023 · Cureus
18. Sex-related differences in the associations between diurnal cortisol pattern and social and emotional loneliness in older adults
    Carmen Díaz Mardomingo, Lucía Utrera, Shishir Baliyan, Sara García‐Herranz, Juan Carlos Suárez-Falcón, Raquel Rodríguez‐Fernández, Patricia Sampedro‐Piquero, Azucena Valencia, César Venero · 2023 · Frontiers in Psychology
19. The mediating role of sport-specific PERMA in the relationship between physical activity/passive sport and global well-being/loneliness
    Daichi Oshimi, Keita Kinoshita, Rei Yamashita · 2023 · Journal of Leisure Research
20. The double-sided coin of loneliness and social media – young adults’ experiences and perceptions
    Emelie Käcko, Jessica Anne Viveka Hemberg, Pia Nyman-Kurkiala · 2024 · International Journal of Adolescence and Youth
21. The examination of the relationships among digital addiction, loneliness, shyness, and social anxiety in adolescents
    Yakup İme, Yusuf Akyıl, Azmi Çağlar · 2024 · Anales de Psicología
22. The impact of PTSD symptoms on suicide ideation in time of terror and war: A nationwide prospective study on the moderating role of loneliness
    Yossi Levi‐Belz, Carmel Blank, Yoav Groweiss, Yuval Neria · 2024 · Psychiatry Research
23. Pathways linking workplace violence and suicidal ideation/non-suicidal self-injury among nurse staff: the mediating role of loneliness and depressive symptoms
    Changmian Ding, Zhizhou Duan, Wenqun Luo, Lidan Li, Guizhi Li, Xuehua Li, Linli Xie, Rongrong Yang · 2024 · BMC Nursing
24. Temporal associations of emotional and social loneliness and psychosocial functioning in emerging adulthood
    Lynn Mobach, Nine E. Wolters, Anke M. Klein, Jurrijn A. Koelen, Peter Vonk, Claudia Maria Van der Heijde, Viviana M. Wuthrich, Ronald M. Rapee, Reinout W. H. J. Wiers · 2024 · Scandinavian Journal of Psychology
25. Workplace loneliness: Relationships with abstract entities as substitutes for peer relationships
    Madison Suzanne LaBella, Daan van Knippenberg · 2024 · Journal of Applied Social Psychology
26. Toward a National Profile of Loneliness in Old-Age China: Prevalence and Lonely Life Expectancy
    Xueqing Wang · 2024 · The Journals of Gerontology Series B
27. Friendship matters: indirect effect of social support from friends on depressive symptoms and loneliness among university students
    Genta Kulari, Luísa Ribeiro, Catarina Tomé‐Pires · 2025 · Studies in Higher Education
28. Social isolation in the young and middle-aged patients with stroke: role of social support, family resilience and hope
    Xiao An Wu, Ke Ke, Hui Liu, Shao Ping Zhan, Lei Wang, Juan He · 2025 · Frontiers in Psychiatry
29. Lonely Minds and Robotic Bonds: Effects of Human Loneliness on the Anthropomorphization of Robots
    Benedikt Leichtmann, Emanuel Gollob, Magdalena Mayer, Anna Katharina Paschmanns, Martina Mara · 2025 · International Journal of Social Robotics
30. Developmentally sensitive markers of personality functioning in adolescents: Age-specific and age-neutral expressions.
    Inge Debast, Gina M. P. Rossi, Dineke Feenstra, Joost Hutsebaut · 2016 · Personality Disorders Theory Research and Treatment
31. The Web of Loneliness: A Netnographic Study of Narratives of Being Alone in an Online Context
    Thomas Johansson, Jesper Andreasson · 2017 · Social Sciences
32. BDNF Val66Met polymorphism modulates the effect of loneliness on white matter microstructure in young adults
    Jie Meng, Hao Chuan Lei, Dongtao Wei, Jiangzhou Sun, Yu Li, Jiang Qiu · 2017 · Biological Psychology
33. Do predictors of mental health differ between home and international students studying in the UK?
    Catrin Jones, Annemarie Lodder, Chris Papadopoulos · 2019 · Journal of Applied Research in Higher Education
34. A SNP , Gene, and Polygenic Risk Score Approach of Oxytocin‐Vasopressin Genes in Adolescents’ Loneliness
    Maaike Verhagen, Karin J. H. Verweij, Gerine M. A. Lodder, Luc Goossens, Karine Verschueren, Karla G. Van Leeuwen, Wim Van Den Noortgate, Stephan J. Claes, Patricia Bijttebier, E. Van Assche et al. · 2019 · Journal of Research on Adolescence
35. Brief induction of loneliness decreases vagal regulation during social information processing
    Aleksandra Piejka, Marcelina Wiśniewska, Julian Francis Thayer, Łukasz Okruszek · 2021 · International Journal of Psychophysiology
36. The Relationship Between Loneliness and Psychological Adjustment: Validation of the Italian Version of the Interpersonal Acceptance–Rejection Loneliness Scale
    Vincenzo Paolo Senese, Carla Nasti, Francesca Mottola, Ida Sergi, Rita Massaro, Augusto Gnisci · 2021 · Frontiers in Psychology
37. Dual trajectories of loneliness and depression and their baseline correlates over a 14‐year follow‐up period in older adults: Results from a nationally representative sample in Taiwan
    I Liu, Yu‐Jen Huang, Liang‐Kai Wang, Yi‐Hsuan Tsai, Sheng-Lun Hsu, Chun‐Jui Chang, Ying‐Hsien Li, Yi‐Chen Hsiao, Chun‐Yuan Chen, Shue‐Ren Wann · 2021 · International Journal of Older People Nursing
38. Social activity promotes resilience against loneliness in depressed individuals: a study over 14-days of physical isolation during the COVID-19 pandemic in Australia
    Julie L. Ji, Julian Basanovic, Colin MacLeod · 2022 · Scientific Reports
39. Are we measuring loneliness in the same way in men and women in the general population and in the older population? Two studies of measurement equivalence
    Thomas Victor Pollet, Alexandra Thompson, Connor Malcolm, Kristofor McCarty, Tamsin K. Saxton, Sam G. B. Roberts · 2022 · PLoS ONE
40. The Role of Personality Variables in Drug Abuse in a Spanish University Population
    José M. García‐Montes, Flor Zaldívar Basurto, Francisca López‐Ríos, Antonio M. Molina Moreno · 2008 · International Journal of Mental Health and Addiction
41. Involvement of the BDNF Gene in Loneliness in Adolescence: A Report of Opposite Gene Effects in Boys and Girls
    Maaike Verhagen, Eeske van Roekel, Rutger C. M. E. Engels · 2014 · PLoS ONE
42. Awareness of risk factors for loneliness among third agers
    Eric Schoenmakers, T.G. van Tilburg, Tineke Fokkema · 2013 · Ageing and Society
43. A Study on Factors Affecting Suicide Risk among Seniors Who Live Alone: The Effect of Loneliness and the Mediating Effect of Hopelessness
    권중돈, 김유진, 엄태영 · 2012 · Health and Social Welfare Review
44. Depression, Loneliness and Cognitive Distortion among Young Unwed Pregnant Women in Malaysia: Counseling Implications
    Rohany Nasir, Zainah Ahmad Zamani, Rozainee Khairudin, Wan Shahrazad Wan Sulaiman, Mohd Norahim Mohamed Sani, Aizan Sofia Amin · 2016 · Asian Social Science
45. Prevalence and Clinical Differences of Suicidal Thoughts and Behaviors in a Community Sample of Youth Receiving Cognitive-Behavioral Therapy for Anxiety
    Nicole Michelle McBride, Carly J. Johnco, Alison Salloum, Adam B. Lewin, Eric A. Storch · 2016 · Child Psychiatry & Human Development
46. The Role of the Quality of College‐Based Relationship on Social Media in College‐to‐Work Transition of Korean College Students: The Longitudinal Examination of Intimacy on Social Media, Social Capital, and Loneliness
    Youngmi Sohn, Sungbum Woo, Duckhyun Jo, Eunjoo Yang · 2018 · Japanese Psychological Research
47. Listen to the voices of the students! The role of peers in academic and social school connectedness
    Marit Andersen, Grete Eide Rønningen, Audhild Løhre · 2019 · Nordisk tidsskrift for pedagogikk og kritikk
48. Beyond the role of loneliness in psychological ill-being and well-being in females: Do social problem-solving processes still matter?
    Edward C. Chang, Weiyi Tian, Xinying Jiang, Shangwen Yi, Jiting Liu, Yuetong Bai, Chang Liu, Xuchi Luo, Weijia Wang, Olivia D. Chang et al. · 2019 · Personality and Individual Differences
49. Promoting resiliency in adolescents during a pandemic: A guide for clinicians and parents
    Ellen S. Rome, Perry B. Dinardo, Veronica Elisabeth Issac · 2020 · Cleveland Clinic Journal of Medicine
50. Loneliness Loves Company, Some More than Others: Social Ties, Form of Engagement, and Their Relation to Loneliness
    R. Gordon Rinderknecht, Long Doan, Liana C. Sayer · 2021 · Social Problems
51. Can You Hear Me Now? Twinship Failure and Chronic Loneliness
    Nancy VanDerHeide · 2012 · International Journal of Psychoanalytic Self Psychology
52. People who need people: Trait loneliness influences positive affect as a function of interpersonal context
    Maria Ditcheva, Suzanne Vrshek‐Schallhorn, Anna Batista · 2018 · Biological Psychology
53. Freedom and loneliness: Dementia caregiver experiences of the nursing home transition
    Holton, Eimile, Boyle, Neasa Bernadette, Simons, Rachel, Warters, Austin, O’Philbin, Laura, Lawlor, Brian, Gibb, Matthew, O’Sullivan, Roger, Pertl, Maria, Quaid, Kevin et al. · 2023 · Age and Ageing
54. The development of adolescents’ loneliness during the COVID-19 pandemic: The role of peer status and contact with friends
    Sofie J. Lorijn, Lydia Laninga‐Wijnen, Maaike Engels, Gerine M. A. Lodder, René Veenstra · 2023 · PLoS ONE
55. Perceived Parental Support and Psychological Control, DNA Methylation, and Loneliness: Longitudinal Associations Across Early Adolescence
    Yentl Koopmans, Stefanie A. Nelemans, Guy Bosmans, Wim Van Den Noortgate, Karla G. Van Leeuwen, Luc Goossens · 2023 · Journal of Youth and Adolescence
56. Loneliness among University students as a growing concerne
    Youssouf Issen Ousman, Thseen Nazır · 2023 · Journal of Family Counseling and Education
57. Links Between Best-Friendship Quality and Well-Being From Early Emerging Adulthood to Early Established Adulthood
    Stéphanie Langheit, François Poulin · 2024 · Emerging Adulthood
58. Preliminary investigation of the regulatory loop of loneliness and the protective role of self-esteem – a cross-sectional study
    Andrej Skoko, Janko M. Kaeser, Noëmi Seewer, Tobias Krieger · 2024 · Current Psychology
59. Relationship between adolescent internet addiction and adolescent non-suicidal self-injury: a moderated mediation model
    Nan Liu, Huaxiang Li, Lin Wang, Jiemei Yin, Aiqin Peng · 2024 · Frontiers in Psychiatry
60. From childhood emotional abuse to adolescent loneliness: The roles of self-compassion and rejection sensitivity
    Yangwenjie Qu · 2024 · Child Abuse & Neglect
61. The impact of retirement on loneliness in Europe
    Sophie Guthmuller, Dörte Heger, Johannes Hollenbach, Anna Werbeck · 2024 · Scientific Reports
62. Lonely and Self-Centered? A Meta-Analysis of the Link Between Prosociality and Loneliness
    Monika Malon, Katarzyna Gajos, Joanna Maria Rajchert, Julianne Holt‐Lunstad, Łukasz Okruszek · 2024 · Personality and Social Psychology Bulletin
63. The Potential Roles of Social Ostracism and Loneliness in the Development of Dark Triad Traits in Adolescents: A Longitudinal Study
    Junwei Pu, Xiong Gan · 2025 · Journal of Personality
64. Theorizing Loneliness in Later Life. Micro, Meso, and Macro Perspectives
    Fredrica Nyqvist, Joanna McHugh Power, Laura Coll‐Planas · 2025 · International perspectives on aging
65. The Psychometric Validity and Reliability of the Turkish Version of the Existential Loneliness Questionnaire
    B. P. Gökdemir-Bulut, Ö. Bozo · 2016 · Current Psychology
66. Identity formation and evaluation in adolescence and emerging adulthood: How is it associated with depressive symptoms and loneliness?
    Nanna Lindekilde, Marlene Lübeck, Mathias Lasgaard · 2018 · Scandinavian Journal of Child and Adolescent Psychiatry and Psychology
67. The use of religious and personal resources in coping with stress during COVID-19 for Palestinians
    Qutaiba Agbaria, Amnah Abu Mokh · 2022 · Current Psychology
68. New evidence on the psychometric properties of the portuguese version of the flourishing scale: measurement invariance across gender
    Belén Rando, Ana María Abreu, María J. Blanca · 2022 · Current Psychology
69. Association between Loneliness, Mental Health Symptoms, and Treatment Use among Emerging Adults
    Melissa L. Bessaha, Dawnsha R. Mushonga, Lisa Fedina, Jordan DeVylder · 2023 · Health & Social Work
70. Loneliness and intersectionality: A progressive conditional approach
    Keming Yang · 2023 · Current Research in Behavioral Sciences
71. Predictive factors of substance misuse and abuse in South Korean adolescents: a secondary data analysis of the 2021 Youth Risk Behavior Web-based Survey
    So Yeon Park, So Yeon Park · 2024 · Child Health Nursing Research
72. The Loneliness of the Long-Distance Radiologist
    Richard B. Gunderman, Allison A. Tillack · 2012 · Journal of the American College of Radiology
73. Mechanisms Mediating Children’s Perceived Maternal Nonsupportive Reactions to Sadness and Children’s Social and Emotional Functioning
    Katianne M. Howard Sharp, Robert Cohen, Katherine M. Kitzmann, Gilbert R. Parra · 2015 · Journal of Child and Family Studies
74. Trauma, Meaning Making, and Loneliness in College Students
    Melissa R. Zeligman, Melanie Varney, Sara Gheesling, Vanessa Placeres · 2018 · Journal of College Student Psychotherapy
75. Romance 2.0 on Instagram! “What Type of Girlfriend Would You Date?”
    Seung‐A Annie Jin, Ehri Ryu, Aziz Muqaddam · 2019 · Evolutionary Psychology
76. Loneliness in Pre and Post-operative Cancer Patients: A Mini Review
    Ami Rokach · 2019 · Emerging Science Journal
77. Loneliness in adolescence: Confirmatory factor analysis of the relational provisions loneliness questionnaire (RPLQ) in a Portuguese sample
    Olívia Ribeiro, António José dos Santos, Miguel Freitas, Antonio Fernando Boleto Rosado, Kenneth H. Rubin · 2019 · International Journal of Behavioral Development
78. Remembrances of parental rejection are associated with loneliness as mediated by psychological maladjustment in young Bangladeshi men but not women
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79. The association between loneliness and common mental disorders in adults with borderline intellectual impairment
    Katerina Papagavriel, Rebecca Jones, Rory Sheehan, Angela Hassiotis, Afia Ali · 2020 · Journal of Affective Disorders
80. Workplace loneliness and employee creativity from a positive perspective
    Sharmeela Abdul Gafoor · 2020 · International Journal of Research in Business and Social Science (2147-4478)
81. Loneliness among in-school adolescents in Ghana: evidence from the 2012 Global School-based Student Health Survey
    Abdul‐Aziz Seidu · 2020 · Journal of Child and Adolescent Mental Health
82. 500 Friends and Still Friending: The Relationship between Facebook and College Students’ Social Experiences
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83. Professores Também Sentem Solidão: Estudo das Características Pessoais e Profissionais de Docentes Associadas à Solidão
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84. Would the Real Loneliness Please Stand Up? The Validity of Loneliness Measures and the Reliability of Single Items
    Marcus Mund, Marlies Maes, Pia Maria Drewke, Antonia Gutzeit, Isabel Jaki, Pamela Qualter · 2021
85. Reduced social contact and attachment insecurity as predictors of loneliness during COVID-19: A two-month experience sampling study
    Katie C. Lewis, Michael J. Roche, Fiona Brown, Jane G. Tillman · 2022 · Personality and Individual Differences
86. Linking workplace loneliness to workplace territoriality: a self-protection perspective
    Qi Nie, Xiao Chen, Guangyu Yu · 2022 · International Journal of Conflict Management
87. Social connectedness to ontological well-being: mediating role of loneliness and death anxiety
    Uzay Ergün, Seydi Ahmet Satıcı · 2023 · Current Psychology
88. The Temporal Relationship between Depressive Symptoms and Loneliness: The Moderating Role of Self-Compassion
    Shujian Wang, Qihui Tang, Yichao Lv, Yanqiang Tao, Xiangping Liu, Liang Zhang, Gang Liu · 2023 · Behavioral Sciences
89. When the antidote is the poison: Investigating the relationship between people’s social media usage and loneliness when face-to-face communication is restricted
    David Jütte, Thorsten Hennig‐Thurau, Gerrit Paul Cziehso, Henrik Sattler · 2024 · PLoS ONE
90. Design of biodegradable cellulose filtration material with high efficiency and breathability
    Jukka A. Ketoja, Kaisa Johanna Saurio, Hille Rautkoski, Eija Kenttä, Atsushi Tanaka, Antti Koponen, Jussi Virkajärvi, Kimmo Heinonen, Katri Kostamo, Anastasia Järvenpää et al. · 2024 · Carbohydrate Polymers
91. Relationship Between Loneliness, Hopelessness, Coping Style, and Mobile Phone Addiction Among Non-Suicidal Self-Injury Adolescents
    Xiaobao Li, Yongjie Zhou, Liang Liu · 2024 · Psychology Research and Behavior Management
92. Examining problematic internet use, mattering, and distress in interpersonally vulnerable senior high school students: A longitudinal study during summer holidays and academic terms
    Jinliang Ding, Xiu‐Mei Chen, Xiao-Ling Liao, Xuelian Wang, I‐Hua Chen, Olga Malas · 2024 · Acta Psychologica
93. Associations between adherence to 24-hour movement guidelines with depression, anxiety, and loneliness among Chinese adolescents
    Ming Hua, Yuxuan Hua, Yuxun Peng, Jingfen Zhu · 2025 · Journal of Affective Disorders
94. Prevalence of Loneliness States Among the U.S. Adult Population: Findings From the 2022 HINTS-6
    Juan Rafael Albertorio‐Diaz, Christopher W. Wheldon · 2025 · American Journal of Preventive Medicine
95. GPs' experiences with loneliness.
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96. Social support, loneliness, eating, and activity among parent–adolescent dyads
    Jessica D. Welch, Erin M. Ellis, Paige A. Green, Rebecca A. Ferrer · 2019 · Journal of Behavioral Medicine
97. Assessment of loneliness in patients with inflammatory arthritis
    Hakan Emmungil, Ufuk İlgen, Sezin Turan, Özge Kılıç · 2020 · International Journal of Rheumatic Diseases
98. Loneliness: An Overlooked Contributing Factor in Anorexia of Older Patients With End-Stage Renal Disease and Focal Point for Interventions to Enhance Nutritional Status—An Overview of Evidence and Areas of Suggested Research
    William A. Wolfe · 2021 · Journal of Renal Nutrition
99. Examining Sexual Assault Victimization and Loneliness as Risk Factors Associated With Nonlethal Self-Harm Behaviors in Female College Students: Is It Important to Control for Concomitant Suicidal Behaviors (and Vice Versa)?
    Edward C. Chang, Jerin Lee, Kaitlin M. Wright, Alexandria S.‐M. Najarian, Tina Yu, Olivia D. Chang, Jameson K. Hirsch · 2016 · Journal of Interpersonal Violence
100. The weighting of positive vs. negative valence and its impact on the formation of social relationships
     Matthew D. Rocklage, Evava S. Pietri, Russell H. Fázio · 2017 · Journal of Experimental Social Psychology