Cited by 196Dementia and Cognitive Impairment ResearchSpeech Recognition and SynthesisArtificial Intelligence in Healthcare

Identifying mild cognitive impairment and mild Alzheimer’s disease based on spontaneous speech using ASR and linguistic features

Gosztolya, Gábor, Vincze, Veronika, Tóth, László, Pákáski, Magdolna, Kálmán, János, Hoffmann, Ildikó·2019·Computer Speech & Language

Abstract

Alzheimer’s disease (AD) is a neurodegenerative disorder that develops for years before clinical manifestation, while mild cognitive impairment is clinically considered as a prodromal stage of AD. For both types of neurodegenerative disorders, early diagnosis is crucial for the timely treatment and to decelerate progression. Unfortunately, the current diagnostic solutions are time-consuming. Here, we seek to exploit the observation that these illnesses frequently disturb the mental and linguistic functions, which might be detected from the spontaneous speech produced by the patient. First, we present an automatic speech recognition based procedure for the extraction of a special set of acoustic features. Second, we present a linguistic feature set that is extracted from the transcripts of the same speech signals. The usefulness of the two feature sets is evaluated via machine learning experiments, where our goal is not only to differentiate between the patients and the healthy control group, but also to tell apart Alzheimer’s patients from those with mild cognitive impairment. Our results show that based on only the acoustic features, we are able to separate the various groups with accuracy scores between 74–82%. We attained similar accuracy scores when using only the linguistic features. With the combination of the two types of features, the accuracy scores rise to between 80–86%, and the corresponding F1 values also fall between 78–86%. We hope that with the full automation…

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Crossref · 10.1016/j.csl.2018.07.007

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References 96 · Cited by 196

Authors
Gosztolya, G., Vincze, V., Tóth, L., Pákáski, M., Kálmán, J., & Hoffmann, I.
Affiliations
  • MTA-SZTE Research Group on Artificial Intelligence (HU)
  • University of Szeged (HU)
Corresponding author
Gosztolya, Gábor
Venue
Computer Speech & Language
Publisher
Elsevier BV
Published
2019-01
Volume
53
Pages
181-197
ISSN
0885-2308 (ISSN-L)
OpenAlex
W2887590219
Cited by
196
References
96
Citations by year
2026: 17 · 2025: 21 · 2024: 23 · 2023: 37 · 2022: 30 · 2021: 35 · 2020: 24 · 2019: 8
FWCI
13.17
Type
journal article
Language
en
Open access
closed
Locations
  • Computer Speech & Language (publishedVersion)
  • SZTE Publicatio Repozitórium (University of Szeged) (acceptedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Physical Sciences › Computer Science › Artificial Intelligence › Speech Recognition and Synthesis
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
Keywords
mild cognitive impairment, Alzheimer's disease, spontaneous speech, speech recognition, acoustic features, linguistic features, early diagnosis, automated screening, neurodegenerative diseases, feature fusion

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