Oral epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: Comparative pharmacokinetics and drug–drug interactions

Peters, Solange, Zimmermann, Stefan, Adjei, Alex A.·2014·Cancer Treatment Reviews

Cited by (163)

Items 101–163 of 163

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  6. FDA-approved small molecule kinase inhibitors for cancer treatment (2001–2015): Medical indication, structural optimization, and binding mode Part I
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  9. Clinical impact of tetracyclines and/or proton pump inhibitors on the efficacy of epidermal growth factor receptor inhibitors in non-small cell lung cancer: a retrospective cohort study
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  10. Impact of performance status and age on osimertinib efficacy in patients with EGFR-mutant T790M-positive non-small-cell lung cancer
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  11. Targeted therapies for lung cancer: how did the game begin?
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  13. A Novel and Efficient Synthesis of Anti-Cancer Agent, Mereletinib
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  14. Osimertinib: A Novel Therapeutic Option for Overcoming T790M Mutations in Non–Small Cell Lung Cancer
    Shan Li, Eve M. Segal · 2017 · Journal of the Advanced Practitioner in Oncology
  15. Potential Drug-Drug Interactions Between Anti-Cancer Drugs and Other Medications in Lung Cancer Patients: A Retrospective Study
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  16. Approved and Clinical Trial Third-Generation EGFR Inhibitors
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  18. A UHPLC–MS/MS method for the quantitation of olmutinib in rat plasma
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  20. Pharmacokinetics and Bioequivalence Evaluation of Erlotinib Hydrochloride Tablets: Randomized, Open‐Label, 2‐Period Crossover Study in Healthy Chinese Subjects
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  21. The alteration of pharmacokinetics of erlotinib and OSI420 in type 1 diabetic rabbits
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  22. Effects of Bojungikkitang (a Polyherbal Formula), on Gefitinib Pharmacokinetics in Rats
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  23. Afatinib, an irreversible ErbB family blocker for the treatment of epidermal growth factor receptor mutation-positive non-small cell lung cancer
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  24. Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines
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  25. Tyrosine-kinase inhibitors for lung or breast cancer and drug–drug interactions: a clinical guide
    Fiorenza Santamaria, Michela Roberto, Giulia Maltese, Francesco Nicolella, Andrea Torchia, Dorelsa Buccilli, Mattia Alberto Di Civita, Paola Giancontieri, Daniele Marinelli, Alessio Cirillo et al. · 2025 · Oncology Reviews
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  27. Therapeutic Targeting of VEGFR-2, PD-L1, and EGFR–MET Pathways in Non-Small Cell Lung Cancer: Clinical Progress with Ramucirumab, Atezolizumab, and Amivantamab
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  28. Primary versus acquired epidermal growth factor receptor Thr790Met mutant non-small cell lung cancer: clinical features and prognoses
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  30. Clinical Challenges to Current Molecularly Targeted Therapies in Lung Cancer
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  31. Effects of Angelica gigas extract on the oral pharmacokinetics of gefitinib in rats
    Hyerim Kim, Jong‐Woo Jeong, Sang Hoon Joo, Tae‐Sung Koo · 2017 · Journal of Pharmaceutical Investigation
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  33. Clinical Pharmacy Practices in Oncology Patients Treated with Tyrosine Kinase Inhibitors
    Aygin Bayraktar‐Ekincioglu · 2018 · International Journal of Hematology and Oncology
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  35. Tuberculosis in epidermal growth factor receptor mutation in lung adenocarcinoma on treatment with gefitinib/erlotinib
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  38. Precision, accuracy, and resolution—Dose selection of oral anticancer agents
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  39. Identification of FDA-Approved Drugs as Modulators of Multidrug Resistance Protein 2 (MRP2/ABCC2) Expression Levels in MRP2-Overexpressing Cells: Preliminary Data
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  40. Non-Small Cell Lung Cancer Treated with Epidermal Growth Factor Receptor Inhibitors: The Effect of Concurrent Medications on Patient Outcomes
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  41. Potential Drug-Drug Interactions With Tyrosine Kinase Inhibitors
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  42. Afatinib
    Giuseppe Tridente · 2017 · Elsevier eBooks
  43. Mitogen-Activated Protein Kinase Signaling and Cancer
    Mutsuhiro Takekawa, Yuji Kubota · 2015 · Springer eBooks
  44. Overview
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  45. A model of NSCLC microenvironment predicts optimal receptor targets
    Chuang Han, Yu Wu · 2019 · Quantitative Biology
  46. Tirosyne Kinase Inhibithors (TKIs) in the Treatment of Non –Small Cell Lung Cancer (NSCLC), Practical Pharmacological Aspects
    Alexandru Călin Grigorescu, Teodorescu Laura Mihaela · 2020 · Journal of Drug Delivery and Therapeutics
  47. Alkalescent soda beverage caused the disappearance of gefitinib-induced rashes and decreased efficacy in a non-small-cell lung cancer patient treated with gefitinib: A case report
    Shuang Bian, Xiaomiao Tang, Sheng Ye, Wei Lei · 2020 · Respiratory Medicine Case Reports
  48. Meme Kanseri Tedavisinde Sinyal Yolaklarının Kritik Rolü
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  49. In silico and in vitro tudies for identification of novel egfr tyrosine kinase inhibitors
    Duangjai Todsaporn · 2021
  50. Revisão Sistemática de Estudos Observacionais sobre o uso de Erlotinibe e Gefitinibe no Tratamento do Câncer de Pulmão de Células Não Pequenas
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  51. Model-Based Evaluation of HangAmDan-B1 and Afatinib Combination Therapy in HCC827 Xenograft Mice with Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
    Sung‐yoon Yang, Lien Thi Ngo, Soyoung Lee, Hwi‐yeol Yun, Tham Thi Bui, Dong-Hyeon Kim, Jung‐woo Chae, Sojung Park · 2025 · Pharmaceuticals
  52. Acidifying agents impact erlotinib and gefitinib pharmacokinetic parameters and elevate liver enzymes in Wistar rats
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  53. Chinese medicine combined with EGFR-TKIs in EGFR-mutated advanced NSCLC: a meta-analysis of efficacy and safety
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  54. BindingDB Entry 50022681: FDA-approved small molecule kinase inhibitors for cancer treatment (2001-2015): Medical indication, structural optimization, and binding mode Part I.
    BindingDB · 2026 · UC San Diego
  55. BindingDB Entry 50003219: Recent updates on third generation EGFR inhibitors and emergence of fourth generation EGFR inhibitors to combat C797S resistance.
    BindingDB · 2020 · UC San Diego
  56. BindingDB Entry 50009645: Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer.
    BindingDB · 2021 · UC San Diego
  57. BindingDB Entry 50013124: Discovery of Dosimertinib, a Highly Potent, Selective, and Orally Efficacious Deuterated EGFR Targeting Clinical Candidate for the Treatment of Non-Small-Cell Lung Cancer.
    BindingDB · 2022 · UC San Diego
  58. BindingDB Entry 50017048: Small Molecule Kinase Inhibitor Drugs (1995-2021): Medical Indication, Pharmacology, and Synthesis.
    BindingDB · 2023 · UC San Diego
  59. BindingDB Entry 50018884: Small Molecule Kinase Inhibitors for the Treatment of Brain Cancer.
    BindingDB · 2024 · UC San Diego
  60. BindingDB Entry 50023144: Structure-Based Design of New LSD1/EGFRL858R/T790M Dual Inhibitors for Treating EGFR Mutant NSCLC Cancers.
    BindingDB · 2026 · UC San Diego
  61. BindingDB Entry 50001303: Design, Synthesis, and Biological Evaluation of Pyrimido[4,5- d]pyrimidine-2,4(1 H,3 H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation.
    BindingDB · 2020 · UC San Diego
  62. BindingDB Entry 50013716: Design, synthesis and biological evaluation of sulfamoylphenyl-quinazoline derivatives as potential EGFR/CAIX dual inhibitors.
    BindingDB · 2022 · UC San Diego
  63. BindingDB Entry 50012225: Design, synthesis and biological evaluation of 2-amino-4-(1,2,4-triazol)pyridine derivatives as potent EGFR inhibitors to overcome TKI-resistance.
    BindingDB · 2022 · UC San Diego