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Cited by 29Balance, Gait, and Falls PreventionDiabetes Management and ResearchPatient Safety and Medication Errors

Severe hypoglycemia and falls in older adults with diabetes: The Diabetes & Aging Study

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Moffet, Howard H., Huang, Elbert S., Liu, Jennifer Y., Parker, Melissa M., Lipska, Kasia J., Laiteerapong, Neda, Grant, Richard W., Lee, Alexandra K. +1 more·2023·Diabetes Epidemiology and Management
DOI 10.1016/j.deman.2023.100162PMC PMC10621321
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Abstract

Objective: To estimate rates of severe hypoglycemia and falls among older adults with diabetes and evaluate their association. Research Design and Methods: Survey in an age-stratified, random sample adults with diabetes age 65-100 years; respondents were asked about severe hypoglycemia (requiring assistance) and falls in the past 12 months. Prevalence ratios (adjusted for age, sex, race/ethnicity) estimated the increased risk of falls associated with severe hypoglycemia. Results: Among 2,158 survey respondents, 79 (3.7%) reported severe hypoglycemia, of whom 68 (86.1%) had no ED visit or hospitalization for hypoglycemia. Falls were reported by 847 (39.2%), of whom 745 (88.0%) had no fall documented in outpatient or inpatient records. Severe hypoglycemia was associated with a 70% greater prevalence of falls (adjusted prevalence ratio = 1.7 (95% CI, 1.3-2.2)). Conclusion: While clinical documentation of events likely reflects severity or care-seeking behavior, severe hypoglycemia and falls are common, under-reported life-threatening events.

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  • Intensive glycemic control reduced retinopathy progression in ACCORD (7.3% vs 10.4%; P = .003) and incidence of nephropathy in ADVANCE (4.1% vs 5.2%; P = .006).

    “Intensive control reduced retinopathy progression in ACCORD (7.3% vs 10.4%; P = .003)42 and incidence of nephropathy in ADVANCE (4.1% vs 5.2%; P = .006).40”

    From Diagnosis and Treatment of Type 2 Diabetes in Adults (2025) · cites this paper as [40]

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References 20 · Cited by 29

Authors
Moffet, H. H., Huang, E. S., Liu, J. Y., Parker, M. M., Lipska, K. J., Laiteerapong, N., Grant, R. W., Lee, A. K., & Karter, A. J.
Affiliations
  • Kaiser Permanente (US)
  • University of Chicago (US)
  • Yale University (US)
  • University of California, San Francisco (US)
Corresponding author
Moffet, Howard H.
ORCID
Venue
Diabetes Epidemiology and Management
Publisher
Elsevier BV
Published
2023-10
Volume
12
Pages
100162
ISSN
2666-9706 (ISSN-L)
DOI
10.1016/j.deman.2023.100162
PMC
PMC10621321
OpenAlex
W4384700244
Cited by
29
References
20
Citations by year
2026: 11 · 2025: 14 · 2024: 4
FWCI
17.89
Type
journal article
Language
en
Open access
Licence
Locations
  • Diabetes Epidemiology and Management (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion, cc-by-nc-nd)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • National Institute on Aging
  • National Institute of Diabetes and Digestive and Kidney Diseases
Topics
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Health Professions › Emergency Medical Services › Patient Safety and Medication Errors
Keywords
severe hypoglycemia, falls, older adults, diabetes mellitus, prevalence

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