BubR1 N Terminus Acts as a Soluble Inhibitor of Cyclin B Degradation by APC/CCdc20 in Interphase

Malureanu, Liviu A., Jeganathan, Karthik B., Hamada, Masakazu, Wasilewski, Lisa, Davenport, James, van Deursen, Jan M.·2009·Developmental Cell

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Items 101–168 of 168

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  2. Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint
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  3. CDC20: a novel therapeutic target in cancer.
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  5. The spindle assembly checkpoint: progress and persistent puzzles
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  13. PP2A-B56γ is required for an efficient spindle assembly checkpoint
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  14. The Kinase Activity of Drosophila BubR1 Is Required for Insulin Signaling-Dependent Stem Cell Maintenance
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  15. BUBR1 Pseudokinase Domain Promotes Kinetochore PP2A-B56 Recruitment, Spindle Checkpoint Silencing, and Chromosome Alignment
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  16. Chromosome cohesion and the spindle checkpoint
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  20. Reprogramming to pluripotency can conceal somatic cell chromosomal instability
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  33. In silico spatial simulations reveal that MCC formation and excess BubR1 are required for tight inhibition of the anaphase-promoting complex
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  44. The Role of APC E3 Ubiquitin Ligase Complex in Tumorigenesis
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  48. Pediatric Glioblastoma Therapies Based on Patient-Derived Stem Cell Resources
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    Francesca Cesari · 2009 · Nature Reviews Molecular Cell Biology
  50. Molecular Mechanisms of Mitotic Spindle Assembly and Accurate Chromosome Segregation
    Yige Guo · 2013
  51. Regulation of Anaphase Promoting Complex/Cyclosome to Control M Phase Exit
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  57. Pediatric Glioblastoma Therapies Based on Patient-Derived Stem Cell Resources
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  58. BUBR1
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  61. siRNA screening of the kinome identified Aurora A kinase as a therapeutic target gene in cervical cancer
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  62. On evolutionary conservation of mitotic checkpoint signaling
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  63. RSK2 et Greatwall, deux AGC kinases actrices de la mitose
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