The Polyploid State Plays a Tumor-Suppressive Role in the Liver

Zhang, Shuyuan, Zhou, Kejin, Luo, Xin, Li, Lin, Tu, Ho-Chou, Sehgal, Alfica, Nguyen, Liem H., Zhang, Yu +4 more·2018·Developmental Cell
DOI 10.1016/j.devcel.2018.01.010

Cited by (154)

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  19. Polyploidy Spectrum Correlates with Immunophenotype and Shapes Hepatocellular Carcinoma Recurrence Following Liver Transplantation
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  26. Raising of Anillin expression in para-cancerous hepatocytes is associated with hepatic depolyploidization and short-term recurrence of hepatocellular carcinoma after radical operation
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  31. Diploid hepatocytes resist acetaminophen-induced liver injury through suppressed JNK signaling
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  41. Ascending E2F7a/b ratio facilitates KLF13 transcription in hepatocellular carcinoma and correlates with the abundance of binuclear hepatocytes ( ABH ) modulation for short‐term recurrence
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  42. Paracancerous binuclear hepatocytes assessed by computer program is a novel biomarker for short term recurrence of hepatocellular carcinoma after surgery
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  44. Blocking cell fusion inhibits age-induced polyploidy and maintains epithelial organization in Drosophila
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  45. PIDDosome-induced p53-activation for ploidy restriction facilitates hepatocarcinogenesis
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  46. Polyploidy in Liver Function, Mitochondrial Metabolism, and Cancer
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  47. Isolation of Mononucleated and Binucleated Hepatocytes by Flow Cytometry
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  51. Constitutive Androstane Receptor induces Ribonucleotide Reductase-M2 expression and maintains hepatocyte ploidy in mice
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