Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair
Zhao, Chuntao, Dong, Chen, Frah, Magali, Deng, Yaqi, Marie, Corentine, Zhang, Feng, Xu, Lingli, Ma, Zhixing +10 more·2018·Developmental Cell
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- The CHD Protein Kismet Restricts the Synaptic Localization of Cell Adhesion Molecules at the Drosophila Neuromuscular JunctionIreland R. Smith, Emily L. Hendricks, Nina K. Latcheva, Daniel R. Marenda, Faith L. W. Liebl · 2024 · International Journal of Molecular Sciences
- The CHD family chromatin remodeling enzyme, Kismet, promotes both clathrin-mediated and activity-dependent bulk endocytosisEmily L. Hendricks, Faith L. W. Liebl · 2024 · PLoS ONE
- Zinc-Finger Protein ZFP488 Regulates the Timing of Oligodendrocyte Myelination and RemyelinationSiying Cui, Tong Chen, Dazhuan Eric Xin, Fangbing Chen, Xiaowen Zhong, Chen Dong, Xiang Chen, Huiyao Chen, Wenhao Zhou, Yifeng Lin et al. · 2024 · Journal of Neuroscience
- Transitions in the proteome and phospho-proteome during Xenopus laevis developmentElizabeth S. Van Itallie, Matthew Sonnett, Marian Kalocsay, Martin Wühr, Leonid Peshkin, Marc W. Kirschner · 2025 · Developmental Biology
- Signaling pathways that regulate glial development and early migration—oligodendrocytesStephen P.J. Fancy, Robert H. Miller · 2020 · Elsevier eBooks
- Specification of oligodendrocytesM. Wegner · 2020 · Elsevier eBooks
- Rise of the Chromodomain Helicase DNA‐Binding (CHD) Chromatin Remodelling MachinesAndrej Alendar · 2023 · Wiley eBooks
- Chd8 haploinsufficiency leads to molecular layer heterotopias and age-dependent cortical expansionFelix A. Kyere, Ian Curtin, Ziquan Wei, César P. Canales, Nicolas Seban, Lei Xing, Preslava P Todorova, Leticia Pérez-Sisqués, Maya Yilan Yin, Tao Wen et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Discovery of oligodendrocyte enhancers that regulate Sox10 expressionHongjoo An, Chuandong Fan, Dongkyeong Kim, Huy Bui, Yungki Park · 2025 · PLoS Genetics
- White matter microstructure of language pathways in non-verbal autism: insights from diffusion tensor imaging and myelin water imagingDominika Slušná, Jordi Muchart Lopez, Wolfram Hinzen, Erick Jorge Canales-Rodríguez · 2025 · Frontiers in Human Neuroscience
- Epigenetic mechanisms of inflammatory memory in the central nervous systemJessica J. Ye, Francisco Javier Quintana · 2026 · Nature Immunology
- Persistent cortical excitatory neuron dysregulation in adult Chd8 haploinsufficient miceCésar P. Canales, Stephanie A. Lozano, Nicholas Alonzo Frost, Karol Cichewicz, Wellington Z. Amaral, Nicolas Seban, Ethan Fenton, A. Ayanna Wade, Nickolas Chu, Emily M. Smith et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Chd8 Deficiency in Zebrafish Causes Autism-Like Behavioral DeficitsHan-Tsing Wang, Xiao-Tong Fu, Ye-Fan Wang, Lingyan Liu, Zhi-Zhi Liu, Hong A. Xu · 2025 · Journal of Integrative Neuroscience
- CHD8 dysregulation in neurodevelopment: Emerging insights into autism pathophysiologyDhrita Chatterjee, Kousik Maparu · 2026 · International Journal of Biological Macromolecules
- Oligodendrocyte Precursor Cells Shape Retinogeniculate Refinement Via a CHD8-Dependent Phagocytic PathwaySiyue Wen, Fengru Guo, Zhidan Li, G. J. Huang, Minghe Shen, Xuelian He · 2026 · Investigative Ophthalmology & Visual Science
- Charting the transition from in vitro gliogenesis to the in vivo maturation of human glial progenitor cells transplanted into the hypomyelinated mouse brainJohn N. Mariani, Steven J. Schanz, Benjamin Mansky, Xiaolu Wei, Carter C. Long, Devin Chandler-Militello, Hannah E. Aichelman, Nguyen P.T. Huynh, Steven A. Goldman · 2026 · Nature Communications
- Homozygous CHD8 mutation intensifies ASD phenotypes and attenuates sex differencesJinkyeong Kim, Seungjoon Lee, Eunkyu Hwang, Hwajin Jung, Chanhee Lee, Sang‐Han Choi, Sooyeon Lee, Seongbin Kim, Heera Moon, Jisoo Kim et al. · 2026 · Molecular Psychiatry
- Defective ventral neurogenesis due to midfetal Chd8 mutation drives autistic-like behavior in miceKenta Nitahara, Atsuki Kawamura, Ayumu Tashiro, Tomoya Iwasaki, Shin-ichi Horike, Jumpei Terakawa, Takiko Daikoku, Koichi Higashi, Ken Kurokawa, Kiyoko Kato et al. · 2026 · Nature Communications
- The Synergistic Roles of Glial Cells and Non-Coding RNAs in the Pathogenesis of Alzheimer’s Disease and Related Dementias (ADRDs)Sydney J. Risen, Devin Wahl, Thomas J. LaRocca, Julie A. Moreno · 2025 · Neuroglia
- Increased cortical volume without increased neuron number in heterozygous Chd8 mutant mouse cortexCésar P. Canales, Samuel Frank, Jeffrey Bennett, Paris Beauregard, Pierre Lavenex, David G. Amaral, Alex S. Nord · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Transitions in the Proteome and Phospho-Proteome During Xenopus laevis DevelopmentElizabeth S. Van Itallie, Marian Kalocsay, Martin Wühr, Leonid Peshkin, Marc W. Kirschner · 2021 · SSRN Electronic Journal
- Clemastine fumarate enhances myelination and promotes functional recovery in a syndromic ASD mouse model of Pitt-Hopkins SyndromeJoseph F. Bohlen, Colin M. Cleary, Debamitra Das, Srinidhi Rao Sripathy, Norah Sadowski, Gina Shim, Rakaia F. Kenney, Ingrid P. Buchler, Daniel Kent Mulkey, Brady J. Maher · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Serum-dependent recruitment of the chromatin remodeler CHD8 to promoters is mediated by the ERK-ELK pathwayAlicia Subtil‐Rodríguez, Elena Vázquez-Chávez, Jose Antonio Guerrero-Martinez, María Ceballos-Chávez, José C. Reyes · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelinationM. E. Rowland, Yan Jiang, S. Shafiq, A. Ghahramani, M. Pena-Ortiz, V. Dumeaux, N. G. Bérubé · 2022 · bioRxiv
- Charting the transition from in vitro gliogenesis to the in vivo maturation of transplanted human glial progenitor cellsJohn N. Mariani, Steven J. Schanz, Benjamin Mansky, Xiaolu Wei, Carter C. Long, Devin Chandler-Militello, Nguyen P.T. Huynh, Steven A. Goldman · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- KMT2E haploinsufficiency manifests autistic-like phenotypes and amygdala abnormality in miceYuan-Jun Li, Chunyan Li, chunyang Li, Dianxing Hu, Zhi-Bo Xv, Shuhan Zhang, Qiang Li, Pei Zhang, Xiaoli Lan, Xiaoqian Chen · 2022 · Research Square
- Polydendrocytes – undifferentiated cells of the nervous systemLarisa V. Vikhareva, E. I. Novikov, E. S. Novikova, A. V. Margaryan · 2022 · Journal of Anatomy and Histopathology
- DYRK1A haploinsufficiency affects the development of astroglia and oligodendroglia, and axonal conductivity in the brainIsabel Pijuan, Elisa Balducci, Cristina Soto‐Sánchez, Eduardo Fernández, Marı́a José Barallobre, Maria Lourdes Arbonés · 2022 · Research Square
- Data from Olig1/2-Expressing Intermediate Lineage Progenitors Are Predisposed to PTEN/p53-Loss–Induced Gliomagenesis and Harbor Specific Therapeutic VulnerabilitiesRavinder Verma, Xiameng Chen, Dazhuan Eric Xin, Zaili Luo, Sean Ogurek, Mei Xin, Rohit Rao, Kalen Berry, Qing Richard Lu · 2023
- Data from Olig1/2-Expressing Intermediate Lineage Progenitors Are Predisposed to PTEN/p53-Loss–Induced Gliomagenesis and Harbor Specific Therapeutic VulnerabilitiesRavinder Verma, Xiameng Chen, Dazhuan Eric Xin, Zaili Luo, Sean Ogurek, Mei Xin, Rohit Rao, Kalen Berry, Qing Richard Lu · 2023
- CHD8 adulthood microglial knockout induces behavioral, morphological, and transcriptional changes in a sex-dependent mannerOrly Weissberg, Dmitrity Getselter, Evan Elliott · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- The CHD Protein, Kismet, Restricts Synaptic BMP Signaling at Glutamatergic SynapsesRachel A. Klaustermeier, Emily L. Hendricks, Joshua A. Preston, Faith L. W. Liebl · 2025 · Neuroscience Insights
- Molecular Interactions of Chd8 in Mouse Brain Highlights a Role in Chromatin-Associated RNA ProcessingEmily Smith, César P. Canales, Mathew W. Kenaston, Nicolas Seban, Ayanna A. Wade, Ethan Fenton, Cory Ardekani, Stephanie Lozano, Nickolas C. Chu, Daniela Perla et al. · 2025 · SSRN Electronic Journal
- Etude du rôle de CHD8 dans les troubles gastro-intestinaux associés aux troubles du spectre autistiqueGaëlle Hayot · 2020
- Role of the cardioprotective protein, Carabin, and its nuclear partners, MLL3 and CHD8, in gene regulation during cardiac hypertrophyRoberto Pane · 2020
- Characterization of Tns3 molecular mechanisms in oligodendrogenesisEmeric Merour · 2021 · theses.fr (ABES)
- Muscone promotes remyelination and alleviates Parkinson’s disease by targeting FKBP5 in MPTP-induced mouse modelJiatian Zhang, Yi Xiao, Anyao Li, Jianfeng Ye, Xiaoping Zhao, Xiaohui Fan, Xiaoyan Lu · 2026 · Journal of Advanced Research
- PAK1 and NF2 antagonist functions in regulating central nervous system myelination : from modulation of oligodendrocyte cytoskeleton to myelin sheath formationNoémie Adès · 2024 · theses.fr (ABES)
- Glial heterogeneity shapes region-specific angiogenesis and neurovascular integrity in the CNSMinghe Shen, Zhidan Li, G. J. Huang, Yue Zhang, Siyue Wen, Fengru Guo, Yingkun Guo, Liguo Zhang, Xuelian He · 2026 · Science Advances
- CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional ProgramsYuanyuan Huang, 胡珍华, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Li Xie, Shilei Bi, Xiaobo Fang et al. · 2026 · Advanced Science