Hospitalizations and inpatient mortality for hyperosmolar hyperglycemic state over a decade
Abstract
Objectives This study aimed to describe rates and trends in hospitalizations, inpatient mortality, total hospital charges, and mean lengths of stay among adult patients hospitalized for hyperosmolar hyperglycemic state (HHS). Methods The study included NIS databases 2008, 2010, 2012, 2014, 2016, and 2018. These databases were searched for hospitalizations with a principal discharge diagnosis of HHS in patients with T2DM using ICD codes (25020, 25022, and E110). Patients less than 18 years, elective hospitalizations, HHS in patients with T1DM or secondary diabetes mellitus were excluded. We used multivariable regression analysis to obtain trends in mortality, length of stay (LOS), and total hospital charges (THC). Results Between 2008 and 2018, there was a trend towards increasing hospitalizations for T2DM with HHS (p trend Conclusions Trends in HHS showed increased hospitalizations, LOS, and THC over the decade in the study period, but inpatient mortality declined.
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Inpatient mortality among people with type 2 diabetes hospitalized for HHS decreased from 1.44% in 2008 to 0.77% in 2018.
“Inpatient mortality among people with type 2 diabetes hospitalized for HHS decreased from 1.44% in 2008 to 0.77% in 2018 (176).”
From 16. Diabetes Care in the Hospital: Standards of Care in Diabetes—2026 (2026) · cites this paper as [176]
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16. Diabetes Care in the Hospital: Standards of Care in Diabetes—2026
American Diabetes Association Professional Practice Committee for Diabetes*, Bajaj, M., McCoy, R. G., Balapattabi, K., Bannuru, R. R., Bellini, N. J., Bennett, A. K., Beverly, E. A., Briggs Early, K., ChallaSivaKanaka, S., et al. (2026) · Diabetes Care · doi:10.2337/dc26-s016 · Cited by 80 · see citing works
- Authors
- Shaka, H., El-amir, Z., Wani, F., Albosta, M., Dahiya, D. S., Alabi, O., Muojieje, C. C., & Kichloo, A.
- Affiliations
- Central Michigan University (US)
- Jacobi Medical Center (US)
- Corresponding author
- Shaka, Hafeez
- Venue
- Diabetes Research and Clinical Practice
- Publisher
- Elsevier BV
- Published
- 2022-03
- Volume
- 185
- Pages
- 109230
- ISSN
- 0168-8227 (ISSN-L)
- OpenAlex
- W4210323703
- Cited by
- 15
- References
- 0
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 4
- FWCI
- 2.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Diabetes Research and Clinical Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- hyperosmolar hyperglycemic state, type 2 diabetes, hospitalization trends, in-hospital mortality, length of hospital stay, hospital charges, temporal trends, Medicare, racial and ethnic disparities
- MeSH terms
- Adult, Aged, Diabetes Mellitus, Type 2, Female, Medicare, Hospitalization, Humans, Hyperglycemic Hyperosmolar Nonketotic Coma, Inpatients, Length of Stay, Male, Middle Aged, United States, Hospital Mortality
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