Physiological consequences of defects in ERCC1–XPF DNA repair endonuclease

Gregg, Siobhán Q., Robinson, Andria Rasile, Niedernhofer, Laura J.·2011·DNA Repair

Cited by (175)

Items 101–175 of 175

  1. Skeletal phenotypes and molecular mechanisms in aging mice
    Qiao Guan, 上海体育大学运动健康学院, 上海 200438, 中国 2上海体育大学竞技运动学院, 上海 200438, 中国, Yuan Zhang, Zhikun Wang, Xiao-Hua Liu, Jun Zou, Ling-Li Zhang · 2024 · 动物学研究
  2. XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes
    Georgia Chatzinikolaou, Kalliopi Stratigi, Athanasios Siametis, Evi Goulielmaki, Alexia Akalestou-Clocher, Ioannis Tsamardinos, Pantelis Topalis, Caroline A. Austin, Britta A. M. Bouwman, Nicola Crosetto et al. · 2023 · Science Advances
  3. Spatial Distribution of Private Gene Mutations in Clear Cell Renal Cell Carcinoma
    Ariane L. Moore, Aashil A. Batavia, Jack Kuipers, Jochen Singer, Elodie Burcklen, Peter Schraml, Christian Beisel, Holger Moch, Niko Beerenwinkel · 2021 · Cancers
  4. Increased Meiotic Crossovers and Reduced Genome Stability in Absence of Schizosaccharomyces pombe Rad16 (XPF)
    Tara L Mastro, Susan L. Forsburg · 2014 · Genetics
  5. Correlation of xeroderma pigmentosum complementation group F expression with gastric cancer and prognosis
    Peilin Li, Yuanzhong Ma · 2018 · Oncology Letters
  6. The XPF-ERCC1 Complex Is Essential for Genome Stability and Is Involved in the Mechanism of Gene Targeting in Physcomitrella patens
    Anouchka Guyon‐Debast, Patricia Rossetti, Florence Charlot, Aline Epert, Jean‐Marc Neuhaus, Didier G. Schaefer, Fabien Nogué · 2019 · Frontiers in Plant Science
  7. Failure to Repair Endogenous DNA Damage in β-Cells Causes Adult-Onset Diabetes in Mice
    Matthew J. Yousefzadeh, Ryan D. O'Kelly, Erin A. Wade, Lisa V. Gonzalez-Espada, Danielle Henessy-Wack, Shannon Howard, Tania A. Rozgaja, Christy E. Trussoni, Nicholas F. LaRusso, Bart J. L. Eggen et al. · 2023
  8. Myelofibrosis in Philadelphia chromosome–negative myeloproliferative neoplasms is associated with aberrant karyotypes
    Gesa Hauck, Danny David Jonigk, Gudrun Göhring, Hans Heinrich Kreipe, Kais Hussein · 2013 · Cancer Genetics
  9. Loss of Ercc1 Results in a Time- and Dose-Dependent Reduction of Proliferating Early Hematopoietic Progenitors
    Judith Verhagen-Oldenampsen, Jurgen R. Haanstra, Paulina M. H. van Strien, Marijke G. Valkhof, Ivo P. Touw, Marieke v. Lindern · 2012 · Anemia
  10. Association between XRCC1 and ERCC1 single-nucleotide polymorphisms and the efficacy of concurrent radiochemotherapy in patients with esophageal squamous cell carcinoma
    Xue Song Huang, Changmin Liu, Yayun Cui, Heping Zhang, Yongping Liu, Xifa Zhou, Judong Luo · 2016 · Oncology Letters
  11. Eukaryotic Nucleotide Excision Repair
    B. Van Houten, Muwen Kong · 2016 · Elsevier eBooks
  12. Measuring biological age in mice using differential mass spectrometry
    Harris Bell‐Temin, Matthew J. Yousefzadeh, Andrey Y. Bondarenko, Ellen K. Quarles, Jacqueline M. Jones-Laughner, Paul D. Robbins, Warren Ladiges, Laura J. Niedernhofer, Nathan A. Yates · 2019 · Aging
  13. Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants
    Bernard Ng, William Casazza, Nam Hee Kim, Chendi Wang, Farnush Farhadi, Shinya Tasaki, David Alan Bennett, Philip L. De Jager, Chris Gaiteri, Sara Mostafavi · 2021 · PLoS Genetics
  14. Multi-Faceted Roles of ERCC1-XPF Nuclease in Processing Non-B DNA Structures
    Tonia T. Li, Karen M. Vásquez · 2022 · DNA
  15. Beyond Nucleotide Excision Repair: The Importance of XPF in Base Excision Repair and Its Impact on Cancer, Inflammation, and Aging
    Dhara Gohil, Rabindra Roy · 2024 · International Journal of Molecular Sciences
  16. The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia
    Edward C. Stanley, Paul A. Azzinaro, David A. Vierra, Niall G. Howlett, Steven Q. Irvine · 2016 · Evolutionary Bioinformatics
  17. The mouse Social Frailty Index (mSFI): a novel behavioral assessment for impaired social functioning in aging mice
    Charles W Collinge, Maria Razzoli, Rachel P. Mansk, Seth McGonigle, Dudley W. Lamming, Christina A. Pacak, Ingrid van der Pluijm, Laura J. Niedernhofer, Alessandro Bartolomucci · 2024 · GeroScience
  18. Inactivation of XPF Sensitizes Cancer Cells to Gemcitabine
    Joseph W. George, Mika Bessho, Tadayoshi Bessho · 2019 · Journal of Nucleic Acids
  19. Can a young muscle's stem cell secretome prolong our lives?
    Karl J. A. McCullagh · 2012 · Stem Cell Research & Therapy
  20. The expression of ERCC1 and BRCA1 predicts prognosis of platinum-based chemotherapy in urothelial cancer
    Hongshun Ma, Wenhui Song · 2016 · OncoTargets and Therapy
  21. Identification of Genes Associated with Lung Adenocarcinoma Prognosis
    Zhehao He, Wang Lv, Luming Wang, Yiqing Wang, Jian Hu · 2019 · Combinatorial Chemistry & High Throughput Screening
  22. The synergy between alkylating agents and ERCC1–XPF inhibitors is p53 dependent
    Gloria Ciniero, Tiago Marques Pedro, Charles Dumontet, Ahmed H. Elmenoufy, Frederick G. West, Michael Weinfeld, Francesco Gentile, Jack A. Tuszyński, Emeline Cros‐Perrial, Lars Petter Jordheim · 2024 · Fundamental and Clinical Pharmacology
  23. ERCC4: a potential regulatory factor in inflammatory bowel disease and inflammation-associated colorectal cancer
    Runjie Shi, Shanping Wang, Ying Jiang, Guoqiang Zhong, Mingsong Li, Yan Sun · 2024 · Frontiers in Endocrinology
  24. Association between ERCC1 Gene Polymorphism (rs11615) and Colorectal Cancer Susceptibility: A Meta-Analysis of Medical Image Fusion and Safety Applications
    Min Liu, Zhifeng Qiu, Qi Yang · 2022 · Computational and Mathematical Methods in Medicine
  25. DNA damage, NF-κB and accelerated aging
    David George Le Couteur, David J. Handelsman · 2012 · Asian Journal of Andrology
  26. Integrating next-generation sequencing and artificial intelligence for the identification and validation of pathogenic variants in colorectal cancer
    Juliana Rodriguez-Salamanca, Mariana Angulo-Aguado, Sarah Orjuela-Amarillo, Catalina Duque, Diana Carolina Sierra-Díaz, Nora Constanza Contreras Bravo, Carlos Figueroa, Carlos Martín Restrepo, Andrés López‐Cortés, Rodrigo Cabrera et al. · 2025 · Frontiers in Oncology
  27. Bisphenol TMC disturbs mitochondrial activity and biogenesis, reducing lifespan and healthspan in the nematode Caenorhabditis elegans
    Laxmi Rathor, Ho Jeong Lee, Taylor McElroy, Steven Beck, Julia Bailey, Yi Sheng, Stephanie Eva Wohlgemuth, Sung‐Hwan Kim, Hun Hwan Kim, Rui Xiao et al. · 2025 · Ecotoxicology and Environmental Safety
  28. Clinical research of individualized therapy in advanced esophageal cancer based on the ERCC1 C8092A genotype
    Yiwei Yao, Yifu He, Xinghua Han, Chu‐Shu Ji, Bing Hu · 2018 · Oncology Letters
  29. Presumed Pathogenic Germ Line and Somatic Variants in African American Thyroid Cancer
    Zachary A. Hurst, Sandya Liyanarachchi, Pamela L. Brock, Huiling He, Fadi A. Nabhan, Colleen Veloski, Amanda Ewart Toland, Matthew David Ringel, Sissy Meihua Jhiang · 2023 · Thyroid
  30. The effect of mesenchymal stem cells administration on DNA repair gene expressions in critically ill COVID-19 patients: prospective controlled study
    Nilgün Işıksaçan, Gökhan Adaş, Pınar Kasapoğlu, Zafer Çukurova, Rabia Yılmaz, Kadriye Kurt Yaşar, Duygu Koyuncu Irmak, Fatıma Ceren Tunçel, Gülçin Şahingöz Erdal, Asuman Gedikbaşı et al. · 2024 · Nucleosides Nucleotides & Nucleic Acids
  31. Spatial distribution of private gene mutations in clear cell renal cell carcinoma
    Ariane L. Moore, Aashil A. Batavia, Jack Kuipers, Jochen Singer, Elodie Burcklen, Peter Schraml, Christian Beisel, Holger Moch, Niko Beerenwinkel · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Unveiling Secondary Mutations in Blended Phenotypes: Dual ERCC4 and OTOA Pathogenic Variants Through WES Analysis
    Pinella Failla, Lucia Saccuzzo, Ornella Galesi, Donatella Greco, Vincenza Barresi, Silvestra Amata, Corrado Romano, Marco Fichera · 2024 · International Journal of Molecular Sciences
  33. A causal role of ATM- and NEMO-dependent NF-κB activation in DNA damage-induced senescence and aging
    Jing Zhao · 2016 · D-Scholarship@Pitt (University of Pittsburgh)
  34. In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
    Alpaslan Öztürk, Tugba Ağbektas, Alakbar Huseynzada, Ruslan Guliyev, Rana Ganbarova, Ulviyya Hasanova, Ayça Taş, Sultan Erkan, Cemile Zontul, Nihal İnandıklıoğlu et al. · 2023 · Life
  35. Genetic and epigenetic predictors of tongue squamous cell carcinoma sensitivity to platinum drugs
    Oleg Ivanovich Kit, Marina A. Engibaryan, Astanda K. Gvaramiya, V.L. Volkova, N. A. Chertova, Denis S. Kutilin · 2024 · Annals of the Russian academy of medical sciences
  36. Development of an IGF1R longevity variant mouse line using CRISPR/Cas9 genome editing
    Yan Dou, Martin Darvas, Kavita Sharma, Julie Mathieu, J. Jason Morton, Heidi Tan, Carolina Soto-Palma, Luise A. Angelini, Sara J. McGowan, Laura J. Niedernhofer et al. · 2020 · Trends in Biomedical Research
  37. Functional relevance of spontaneous alternative splice variants of xeroderma pigmentosum genes: Prognostic marker for skin cancer risk and disease outcome?
    Janin Lehmann · 2017
  38. ERCC1-XPF Interacts with Topoisomerase IIβ to Facilitate the Repair of Activity-induced DNA Breaks
    Georgia Chatzinikolaou, Kalliopi Stratigi, Kyriacos Agathangelou, Maria Tsekrekou, Evi Goulielmaki, Ourania Chatzidoukaki, Katerina Gkirtzimanaki, Tamara Aid‐Pavlidis, Michalis Aivaliotis, Pavlos Pavlidis et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  39. Bisphenol TMC disturbs mitochondrial activity and biogenesis, reducing lifespan and healthspan in the nematode Caenorhabditis elegans
    Laxmi Rathor, Ho Jeong Lee, Taylor McElroy, Steven Beck, Julia Bailey, Stephanie Eva Wohlgemuth, Sung‐Hwan Kim, Jeong‐Doo Heo, Rui Xiao, Sung Min Han et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  40. Cyclin D1 regulates the hepatic response to feeding: Evidence for non-cell cycle roles in the liver
    Heng Wu, Jonathan I Hauser, Na Yang, Nikolai Timchenko, Maggie Klaers, Rahagir Salekeen, Juan Carlos Manivel, Juan E. Abrahante, Linshan Laux, Matthew J. Yousefzadeh et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  41. The Contribution of DNA Interstrand Crosslinks to Aging
    Andria Rasile Robinson · 2012 · D-Scholarship@Pitt (University of Pittsburgh)
  42. Mecanismos de reparo de DNA envolvidos com lesões induzidas por agente alquilante (Nimustina) em células humanas e sua associação com a resistência de gliomas.
    Juliana Brandstetter Vilar · 2014 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  43. The development and application of SNP discovery technologies from 2005 to 2012
    James P. Colley · 2012 · ORCA Online Research @Cardiff (Cardiff University)
  44. Investigating the genetics and pharmacogenetics of bowel cancer
    Hannah D. West · 2013 · ORCA Online Research @Cardiff (Cardiff University)
  45. Endogenous DNA damage drives cellular senescence and promotes aging
    Siobhán Q. Gregg · 2011 · D-Scholarship@Pitt (University of Pittsburgh)
  46. Personalized Cancer Therapy for Urological Cancers: From Bench to Bedside and Back
    Hirotsugu Uemura, Colleen C. Nelson, Jack A. Schalken, Laurence H. Klotz · 2012 · Advances in Urology
  47. The role of nucleotide excision repair factors and the Mre11 nuclease in nucleoside analogue sensitivity
    Richard Beardmore · 2015 · Bangor University Research Portal (Bangor University)
  48. The aging immune system and nutritional interventions
    Adriaan A. van Beek · 2017
  49. Third EU-US workshop on “Nucleotide excision repair and crosslink repair—From molecules to mankind”, Smolenice Castle, Slovak Republic, May 7th–11th 2017
    Peter J. McHugh, Caroline Kisker, Miroslav Chovanec, Bennett Van Houten · 2017 · DNA repair
  50. Clinicopathological correlation of the expression of excision repair cross complementation group 1 (ERCC1) in oral cavity squamous cell carcinomas: an immunohistochemical study
    Deepthi Pankaj, Vasudeva Guddattu, M.C. Solomon · 2020 · Experimental Oncology
  51. DNA damage and repair in aging
    Ajinkya S. Kawale, Patrick Sung · 2021 · Elsevier eBooks
  52. AGING WITH T CELLS
    Pieren, Daniël Kees Johan · 2021
  53. DNA damage in tissue-resident macrophages leads to age-related neurodegeneration
    George A. Garinis, Katerina Gkirtzimanaki, Edisona Tsakani, Ermioni S. Arvanitaki, Electra Nenedaki, Maria Kefalogianni, Georgios Niotis, Ilias Kalafatakis, Evi Goulielmaki, Sotiris Psilodimitrakopoulos et al. · 2021 · Research Square
  54. Faculty Opinions recommendation of Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia.
    Matthew M. Heeney, Raffaele Renella · 2013 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  55. Faculty Opinions recommendation of ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures.
    Nei‐Li Chan, Peter Chi · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  56. Faculty Opinions recommendation of Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging.
    Björn Schumacher · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  57. Faculty Opinions recommendation of The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
    Robert F. Casper · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  58. Eukaryotic Nucleotide Excision Repair
    Bennett Van Houten, Muwen Kong · 2016 · Elsevier eBooks
  59. Two siblings with Fanconi anemia (FANCQ, ERCC4/XPF) presenting with tumor‐mimicking lesions in the brain and acute neurological deterioration
    Zeynep Canan Özdemir, Çoşkun Yarar, Çiğdem Öztunalı, Ersin Töret, Kürşat Bora Çarman, Özcan Bör · 2024 · Pediatric Blood & Cancer
  60. Role of the nucleotide excision repair endonuclease XPF in the kinetoplastid parasite Trypanosoma brucei
    Claudia Gómez-Liñán, María Sáez-Maldonado, Laura Montosa-Hidalgo, Luis Miguel Ruiz-Pérez, Dolores González‐Pacanowska, Antonio E. Vidal · 2025 · Scientific Reports
  61. Transcriptional stress in aging: integrating experimental data and modeling to quantify DNA damage accumulation
    Jacinta van de Grint, Marko Rašeta, Renata M. C. Brandt, Yvette van Loon, Joris J. P. G. Demmers, Shannon Dealy, Jiang Chang, Jan H.J. Hoeijmakers, Joris Pothof · 2025 · Frontiers in Molecular Biosciences
  62. Cap a un model complet de la xarxa molecular alterada en l’anèmia de Fanconi i el càncer de mama
    Griselda Martrat Sànchez · 2012 · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
  63. Additional file 6 of Comparative transcriptomic analysis of deep- and shallow-water barnacle species (Cirripedia, Poecilasmatidae) provides insights into deep-sea adaptation of sessile crustaceans
    Gan, Zhibin, Yuan, Jianbo, Liu, Xinming, Dong, Dong, Li, Fuhua, Li, Xinzheng · 2020 · Figshare
  64. Additional file 4 of Comparative transcriptomic analysis of deep- and shallow-water barnacle species (Cirripedia, Poecilasmatidae) provides insights into deep-sea adaptation of sessile crustaceans
    Gan, Zhibin, Yuan, Jianbo, Liu, Xinming, Dong, Dong, Li, Fuhua, Li, Xinzheng · 2020 · Figshare
  65. Additional file 7 of Comparative transcriptomic analysis of deep- and shallow-water barnacle species (Cirripedia, Poecilasmatidae) provides insights into deep-sea adaptation of sessile crustaceans
    Gan, Zhibin, Yuan, Jianbo, Liu, Xinming, Dong, Dong, Li, Fuhua, Li, Xinzheng · 2020 · Figshare
  66. Additional file 1 of Comparative transcriptomic analysis of deep- and shallow-water barnacle species (Cirripedia, Poecilasmatidae) provides insights into deep-sea adaptation of sessile crustaceans
    Gan, Zhibin, Yuan, Jianbo, Liu, Xinming, Dong, Dong, Li, Fuhua, Li, Xinzheng · 2020 · Figshare
  67. Additional file 2 of Comparative transcriptomic analysis of deep- and shallow-water barnacle species (Cirripedia, Poecilasmatidae) provides insights into deep-sea adaptation of sessile crustaceans
    Gan, Zhibin, Yuan, Jianbo, Liu, Xinming, Dong, Dong, Li, Fuhua, Li, Xinzheng · 2020 · Figshare
  68. Additional file 8 of Comparative transcriptomic analysis of deep- and shallow-water barnacle species (Cirripedia, Poecilasmatidae) provides insights into deep-sea adaptation of sessile crustaceans
    Gan, Zhibin, Yuan, Jianbo, Liu, Xinming, Dong, Dong, Li, Fuhua, Xinzheng Li · 2020 · Figshare
  69. Additional file 3 of Comparative transcriptomic analysis of deep- and shallow-water barnacle species (Cirripedia, Poecilasmatidae) provides insights into deep-sea adaptation of sessile crustaceans
    Gan, Zhibin, Yuan, Jianbo, Liu, Xinming, Dong, Dong, Li, Fuhua, Li, Xinzheng · 2020 · Figshare
  70. Additional file 5 of Comparative transcriptomic analysis of deep- and shallow-water barnacle species (Cirripedia, Poecilasmatidae) provides insights into deep-sea adaptation of sessile crustaceans
    Gan, Zhibin, Yuan, Jianbo, Liu, Xinming, Dong, Dong, Li, Fuhua, Li, Xinzheng · 2020 · Figshare
  71. RNA as a genome architect: G-loops in G-quadruplex regulation
    Jie Wang, Zhaojie Lyu, Qi Zhang, William C. Cho, De-Chao Feng · 2025 · Military Medical Research
  72. Case Report: A case with Xeroderma pigmentosum type F manifested a mild phenotype due to a deep intronic variant of the ERCC4 gene
    Mei Tochigi, Yuko Takamiya, Megumi Morita, Kazushi Anzawa, Akira Shimizu, Sumihito Togi, Hiroki Ura, Yo Niida · 2026 · Journal of Cutaneous Immunology and Allergy
  73. A manually curated gene-phenotype catalogue for progeroid syndromes and premature aging
    Nuša Likar, Tanja Kunej · 2026 · Aging
  74. Sumo-Directed Control of the Resolvase Yen1 in Mitotic Cells
    Hugo Dorison · 2021 · theses.fr (ABES)
  75. Linking The Multiple Functions of XPF-ERCC1 Endonuclease in DNA Repair to Health Outcomes: Cancer and Aging
    Advaitha Madireddy · 2012 · D-Scholarship@Pitt (University of Pittsburgh)