Applications of Connectivity Map in drug discovery and development

Qu, Xiaoyan A., Rajpal, Deepak K.·2012·Drug Discovery Today

Cited by (237)

Items 201–237 of 237

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  4. Network Pharmacology Study of the Shexiang Baoxin Pill
    Jing Zhao, Peng Jiang, Runui Liu, Weidong Zhang · 2018 · Elsevier eBooks
  5. Screening of Medications for Idiopathic Membranous Nephropathy Using Glomerular Whole-Genome Sequencing
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  6. Old drugs and new opportunities—Drug repurposing in colon cancer prevention
    Vemula Sarojamma, Manoj Kumar Gupta, Jeelan Basha Shaik, Ramakrishna Vadde · 2023 · Elsevier eBooks
  7. RNCE: network integration with reciprocal neighbors contextual encoding for multi-modal drug community study on cancer targets
    Junyi Chen, Ka‐Chun Wong · 2020 · Briefings in Bioinformatics
  8. Identification of Novel Drugs Targeting Cell Cycle Regulators for the Treatment of High-Grade Serous Ovarian Cancer via Integrated Bioinformatics Analysis
    Yuanchun Zhao, Jiachen Zuo, Yiming Shen, Donghui Yan, Jiajia Chen, Xin Qi · 2022 · Symmetry
  9. Búsqueda racional de nuevos fármacos antichagásicos inhibidores de la cruzipaína
    Carolina L. Bellera · 2014
  10. Cellular Assays
    Fang Ye · 2017 · Methods and principles in medicinal chemistry
  11. Probabilistic components of molecular interactions and drug responses
    Juuso Parkkinen · 2014 · Aaltodoc (Aalto University)
  12. Validating a novel ADHD model for medication development
    Petra Majdak · 2016 · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
  13. Application of Connectivity Map (CMAP) Database to Research on Traditional Chinese Medicines (TCMs)
    Chao Lv, Dale G. Nagle, Yudong Zhou, Weidong Zhang · 2018 · Elsevier eBooks
  14. Tamizado virtual aplicado a la búsqueda de nuevos fármacos antiepilépticos activos en el modelo de 6 Hz
    Sofía Goicoechea · 2020
  15. Identification of Hub Genes And Pathways of Gastric Adenocarcinoma Using Bioinformatics Analysis
    Yu Di · 2021 · Research Square
  16. Computational-driven understanding of the regulatory mechanisms of the breast cancer transcriptome and its implications for drug treatment
    Shujun Huang · 2021 · Mspace (University of Manitoba)
  17. A Novel Prognostic Model Based on Nine-Targeted Therapeutic Response Relevant Secreted Protein Genes (Trspgs) from Single-Cell Rna Sequencing in Multiple Myeloma
    Liping Zeng, Ting Yin, Linyi Zhang, Sixuan Guo, Chuangqin Pu, Lugui Qiu, Min Yu, Fei Li · 2022 · SSRN Electronic Journal
  18. Organ-Specific Treatment for COVID-19: Rationale, Evidence, and Potential Candidates
    Mojdeh Rahmanian, Seyedeh Zahra Mousavi, Ashkan Sami · 2020 · ChemRxiv
  19. Repurposing of Drug: Utility of Animal Models
    Muskan Aggarwal, Trishi A. Mehta, Aparimita Das, Alakesh Das, N. R. Shruthi, Surajit Pathak · 2022 · Handbook of Animal Models and its Uses in Cancer Research
  20. Repurposing of Drug: Utility of Animal Models
    Muskan Aggarwal, Trishi A. Mehta, Aparimita Das, Alakesh Das, N. R. Shruthi, Surajit Pathak · 2023 · Handbook of Animal Models and its Uses in Cancer Research
  21. Hyperbolic Manifold Learning on Differential Expression Signatures
    Domonkos Pogány, Péter Antal · 2023
  22. Hyperbolic Manifold Learning on Differential Expression Signatures
    Domonkos Pogány, Péter Antal · 2023
  23. Augmenting Predictive Accuracy in Pharmacological Mechanism of Action Models through Complementary Penalization Metrics and Variational Feature Selection
    V Abhijith Narayan Rao · 2024
  24. Melasolv™: a potential preventive and depigmenting agent for the senescence of melanocytes
    Yeonju Cho, Suh-Yeon Choi, Hyunjung Choi, Mira Ham, Kyu-Han Kim · 2024 · Frontiers in Molecular Biosciences
  25. Additional file 5 of Indirubin, a small molecular deriving from connectivity map (CMAP) screening, ameliorates obesity-induced metabolic dysfunction by enhancing brown adipose thermogenesis and white adipose browning
    Gang Wei, Honglin Sun, Jun‐Li Liu, Kai Dong, Jun‐Li Liu, Min Zhang · 2020 · Figshare
  26. Additional file 4 of Indirubin, a small molecular deriving from connectivity map (CMAP) screening, ameliorates obesity-induced metabolic dysfunction by enhancing brown adipose thermogenesis and white adipose browning
    Gang Wei, Honglin Sun, Junli Liu, Kai Dong, Jun‐Li Liu, Min Zhang · 2020 · Figshare
  27. Novel tumor gene expression signatures improve the overall survival prediction efficiency over tumor mutation burden and PD-L1 expression in bladder carcinoma with checkpoint blockade immunotherapy
    Yufeng Guo · 2024 · American Journal of Cancer Research
  28. Advanced RPL19-TRAPKI-seq method reveals mechanism of action of bioactive compounds
    Di Zhu, Junchi Hu, Renke Tan, Xiaofeng Lin, Ruina Wang, Junyan Lu, Biao Yu, Yongmei Xie, Xiaohua Ni, Chunmin Liang et al. · 2025 · Natural Products and Bioprospecting
  29. Augmenting Predictive Accuracy in Pharmacological Mechanism of Action Models
    V Abhijith Narayan Rao, M. Sanjay · 2024 · International Conference on Computational Biology and Bioinformatics (ICCBB)
  30. Hyperbolic Nature of Differential Expression Signatures
    Domonkos Pogány, Péter Antal · 2025 · IEEE Transactions on Computational Biology and Bioinformatics
  31. Additional file 1 of Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways
    Tran, Thu-Ha, Kao, Ming, Liu, Hsiao-Sheng, 洪義人, Yeu Su, Huang, Chi-Ying F. · 2023 · Figshare
  32. Additional file 1 of Indirubin, a small molecular deriving from connectivity map (CMAP) screening, ameliorates obesity-induced metabolic dysfunction by enhancing brown adipose thermogenesis and white adipose browning
    Wei, Gang, Sun, Honglin, Liu, Jun-li, Dong, Kai, Liu, Junli, Zhang, Min · 2020 · Figshare
  33. Additional file 2 of Indirubin, a small molecular deriving from connectivity map (CMAP) screening, ameliorates obesity-induced metabolic dysfunction by enhancing brown adipose thermogenesis and white adipose browning
    Wei, Gang, Sun, Honglin, Liu, Jun-li, Dong, Kai, Liu, Junli, Zhang, Min · 2020 · Figshare
  34. Additional file 3 of Indirubin, a small molecular deriving from connectivity map (CMAP) screening, ameliorates obesity-induced metabolic dysfunction by enhancing brown adipose thermogenesis and white adipose browning
    Wei, Gang, Sun, Honglin, Liu, Jun-li, Dong, Kai, Liu, Junli, Zhang, Min · 2020 · Figshare
  35. In silico disruption of TGF-β signalling in AR-deficient triple-negative breast cancer via AMP-based therapeutics
    Anurupa Chakraborty, Zarin Taj, Kamalavannan Raashika, L.C. Singh, Indranil Chattopadhyay · 2025 · In Silico Research in Biomedicine
  36. AI-Driven Drug Repurposing Strategies for Precision Therapy in Breast Cancer
    Bharath Kumar Jakkula, Perugu Shyam · 2026 · Pharmaceutical science.
  37. Perturb-Seqr: Signature Search Engine Integrating Connectivity Mapping Resources
    Lily D. Taub, J. K. Gardner, Ido Diamant, Daniel J. B. Clarke, Avi Ma’ayan · 2026 · bioRxiv (Cold Spring Harbor Laboratory)