Mother–child interaction and cognitive development in children prenatally exposed to methadone or buprenorphine
Abstract
Objective To assess the influence of mother-child interaction on children's cognitive development in a group of children prenatally exposed to methadone or buprenorphine. Study design The study is part of a prospective longitudinal project investigating the development of children born to women in opioid maintenance therapy (OMT). The sample includes 67 children born between 2005 and 2007, 35 of which prenatally exposed to either methadone or buprenorphine and 32 non-exposed comparison children. Results Both groups scored within the normal range of development. However, the OMT group scored significantly lower on measures of cognitive development and mother-child interaction compared to the comparison group. Cognitive development was found to be affected by both group status, F(1,54)=5.65, p=0.02, η(2)=0.10 and mother-child interaction F(1,54)=5.26, p=0.03, η(2)=0.09. Behavioral inhibition (statue), sensorimotor function (imitating hand positions), and short-term memory (sentences) was influenced by group status while narrative memory and vocabulary were found to be more influenced by mother-child interaction. Conclusions Different risk factors may influence different cognitive functions in children of women in OMT. Specifically, language-related cognitive skills may be more related to mother-child interaction while performance in higher cognitive functions requiring precise control over sensorimotor responses may be more sensitive to other factors such as prenatal OMT exposu…
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Perinatal substance use tends to have a detrimental effect on mother-child bonding.
“Also perinatal substance use tends to have a detrimental effect on mother-child bonding, as illustrated in many studies (50, 51).”
From Mothering, Substance Use Disorders and Intergenerational Trauma Transmission: An Attachment-Based Perspective (2019) · cites this paper as [51]
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- Authors
- Konijnenberg, C., Sarfi, M., & Melinder, A.
- Affiliations
- University of Oslo (NO)
- Corresponding author
- Konijnenberg, Carolien
- Venue
- Early Human Development
- Publisher
- Elsevier BV
- Published
- 2016-10
- Volume
- 101
- Pages
- 91-97
- ISSN
- 0378-3782 (ISSN-L)
- OpenAlex
- W2514311270
- Cited by
- 63
- References
- 52
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 6 · 2023: 8 · 2022: 8 · 2021: 10 · 2020: 7 · 2019: 8 · 2018: 4 · 2017: 3
- FWCI
- 5.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Early Human Development (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Keywords
- mother-child interaction, cognitive development, prenatal opioid exposure, methadone, buprenorphine, opioid maintenance treatment, behavioral inhibition, sensorimotor function, short-term memory, narrative memory, vocabulary, language development
- MeSH terms
- Adult, Buprenorphine, Child Development, Cognition, Female, Humans, Infant, Newborn, Language Development, Male, Memory, Methadone, Mother-Child Relations, Narcotic Antagonists, Pregnancy, Prenatal Exposure Delayed Effects, Psychomotor Performance, Case-Control Studies, Opiate Substitution Treatment
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