NovoTTF-100A versus physician’s choice chemotherapy in recurrent glioblastoma: A randomised phase III trial of a novel treatment modality

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1. Tumor treating fields can effectively overcome trastuzumab resistant breast cancer multiplication.
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2. Expert guidance on prophylaxis and treatment of dermatologic adverse events with Tumor Treating Fields (TTFields) therapy in the thoracic region
   Milan J. Anadkat, Mario E. Lacouture, Adam Friedman, Zachary D. Horne, Jae Ung Jung, Benjamin Harris Kaffenberger, Sujith Rao Kalmadi, Liza G. Ovington, Rupesh R Kotecha, Huda Ismail Abdullah et al. · 2023 · Frontiers in Oncology
3. Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
   Ayman I. Omar · 2014 · Journal of Visualized Experiments
4. The immune-related microRNA miR-146b is upregulated in glioblastoma recurrence
   Shariq S. Khwaja, Chunyu Cai, Shahed Nicolas Badiyan, Xiaowei Wang, Jiayi Huang · 2018 · Oncotarget
5. Tumor Treating Fields: Adjuvant Treatment for High-grade Gliomas
   Patricia P. Anthony, Stacey McArdle, Michele McHugh · 2018 · Seminars in Oncology Nursing
6. A Thermal Study of Tumor-Treating Fields for Glioblastoma Therapy
   Nichal Gentilal, Ricardo Salvador, Pedro Cavaleiro Miranda · 2020 · Springer eBooks
7. Investigational treatment strategies in glioblastoma: progress made and barriers to success
   Thomas Allen Nelson, Jörg Dietrich · 2023 · Expert Opinion on Investigational Drugs
8. Prognosis of glioblastoma patients improves significantly over time interrogating historical controls
   Alice Thomas-Joulié, Suzanne Tran, L. El Houari, Antoine Seyve, Franck Bielle, Cristina Birzu, Fernando Alcides Lozano-Sánchez, Karima Mokhtari, Marine Giry, Yannick Marie et al. · 2024 · European Journal of Cancer
9. Advanced tumor electric fields therapy: A review of innovative research and development and prospect of application in glioblastoma
   Jinxin Lan, Yuyang Liu, Junyi Chen, Hongyu Liu, Yaping Feng, Jialin Liu, Ling Chen · 2024 · CNS Neuroscience & Therapeutics
10. Molecular characterization leads the way
    Roger Stupp, Monika E. Hegi · 2013 · Nature Reviews Clinical Oncology
11. Re-irradiation of recurrent glioblastoma as part of a sequential multimodality treatment concept
    Elisabeth Bräutigam, Christian Lampl, Christine Track, Carsten Nieder, Josef Pichler, Josef Hammer, Hans Geinitz · 2018 · Clinical & Translational Oncology
12. Repeat radiation with bevacizumab and minocycline in bevacizumab-refractory high grade gliomas: a prospective phase 1 trial
    Adam Louis Cohen, Christopher James Anker, Brett Johnson, Lindsay Burt, Dennis C. Shrieve, Karen L. Salzman, Randy L. Jensen, Kenneth M. Boucher, Howard Colman · 2020 · Journal of Neuro-Oncology
13. Tumor-treating fields as a proton beam-sensitizer for glioblastoma therapy.
    Won Seok Lee, Seung‐Jun Seo, Hye Kyung Chung, Jang Woo Park, Jong-Ki Kim, Eun Ho Kim · 2021 · PubMed Central
14. Effect of duty cycles of tumor‑treating fields on glioblastoma cells and normal brain organoids
    Eunbi Ye, Jung Eun Lee, Young-Soo Lim, Seung Yang, Sung‐Min Park · 2021 · International Journal of Oncology
15. SapC-DOPS nanovesicles: a novel targeted agent for the imaging and treatment of glioblastoma
    Victor Blanco, Richard Charles Curry, Xiaoyang Qi · 2015 · Oncoscience
16. In Vitro Validation of Intratumoral Modulation Therapy for Glioblastoma.
    Hongzhi Xu, Frank Bihari, Shawn Narain Whitehead, Eugene Wong, Susanne Schmid, Matthew O. Hebb · 2016 · PubMed
17. Programmable Modulation for Extracellular Vesicles
    Yihua Wang, Richard Melvin, Lynne Bemis, Gregory A. Worrell, Hai-Long Wang · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
18. Phase 2 trial of personal dendritic cell vaccines in newly diagnosed glioblastoma: 3-year follow-up and correlations with survival
    Daniela Annenelie Bota, David Eric Piccioni, Christopher Duma, Santosh Kesari, Jose Carrillo, Renato V. LaRocca, Robert D. Aiken, Thomas H. Taylor, Mehrdad Abedi, Rockelle M. Robles et al. · 2025 · Human Vaccines & Immunotherapeutics
19. Skull defect increases the tumor treating fields strength without detrimental thermogenic effect: A computational simulating research
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20. Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells
    Shashank Hambarde, Jeanne M. Manalo, David S. Baskin, Martyn A. Sharpe, Santosh A. Helekar · 2023 · Scientific Reports
21. Tumor treating fields for the treatment of glioblastoma: Current understanding and future perspectives
    Antonio Colamaria, Augusto Leone, Nicola Pio Fochi, Veronica Di Napoli, Guido Giordano, Matteo Landriscina, Kashyap B Patel, Francesco Carbone · 2023 · Surgical Neurology International
22. Tumor treating fields: narrative review of a promising treatment modality for cancer
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23. Research Progress on the Mechanism of Anti-Tumor Immune Response Induced by TTFields
    Yue Lan, Shaomin Zhang, Yun Pan, Minmin Wang, Guangdi Chen · 2023 · Cancers
24. New progress in the treatment of diffuse midline glioma with H3K27M alteration
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25. Advancements and current trends in tumor treating fields: a scientometric analysis
    Yang Xing, Feroza Yasinjan, Jiayue Cui, Yizhao Peng, Minghua He, Wenhui Liu, Xinyu Hong · 2024 · International Journal of Surgery
26. Tumor Treating Fields (TTFields) induce homologous recombination deficiency in ovarian cancer cells, thus mitigating drug resistance
    Yani Berckmans, Hila M. Ene, Kerem Ben‐Meir, Antonia Martinez-Conde, Roxanne Wouters, Bieke Van den Ende, Sara Van Mechelen, Roni Monin, Roni Frechtel-Gerzi, Hila Gabay et al. · 2024 · Frontiers in Oncology
27. Highlighting the need for reliable clinical trials in glioblastoma
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28. Longitudinal, leakage corrected and uncorrected rCBV during the first-line treatment of glioblastoma: a prospective study
    Eike Steidl, Mathias M. Müller, Andreas Müller, Ulrich Herrlinger, Elke Hattingen · 2019 · Journal of Neuro-Oncology
29. Tumor Treating Fields for Ovarian Carcinoma: A Modeling Study
    Edwin Lok, Pyay San, VICTORIA M. WHITE, Olivia Liang, Page C. Widick, Sindhu Reddy Pisati, Eric T. Wong · 2021 · Advances in Radiation Oncology
30. Safety of Tumor Treating Fields (TTFields) therapy in pediatric patients with malignant brain tumors: Post-marketing surveillance data
    Stewart Goldman, Ashley Margol, Eugene I. Hwang, Kazuhiro Tanaka, Bogdana Suchorska, John Ross Crawford, Santosh Kesari · 2022 · Frontiers in Oncology
31. A feasibility study of the Nativis Voyager ® device in patients with recurrent glioblastoma in Australia
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32. Central Nervous System Cancers
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33. Immunotherapy and radiation for high-grade glioma: a narrative review
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34. Tumor Treating Fields for Glioblastoma Therapy During the COVID-19 Pandemic
    Na Tosha Gatson, Jill S. Barnholtz‐Sloan, Jan Drappatz, Roger Henriksson, Andreas Felix Hottinger, Piet Hinoul, Carol A. Kruchko, Vinay K. Puduvalli, David Dinh Tran, Eric T. Wong et al. · 2021 · Frontiers in Oncology
35. Limited survival benefit in patients diagnosed with glioblastoma post-2016: a SEER population based registry analysis
    Shaurya Dhingra, Matthew Koshy, Mark Charles Korpics · 2025 · Journal of Cancer Research and Clinical Oncology
36. Comparative efficacy and safety of therapeutics for elderly glioblastoma patients: A Bayesian network analysis
    Binghao Zhao, Jiaming Wu, Yu Xia, Huanzhang Li, Yaning Wang, Tian Qu, Hao Xing, Yu Wang, Wenbin Ma · 2022 · Pharmacological Research
37. Tumor treating fields increases blood-brain barrier permeability and relative cerebral blood volume in patients with glioblastoma
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38. HMGB2 is a biomarker associated with poor prognosis promoting radioresistance in glioma by targeting base excision repair pathway
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39. Implantable Ultrasound‐Powered MXene/PVA Hydrogel‐Based Generator for Treatment of Glioblastoma
    Xiaoping Hu, Ziyi Qiu, Yilin Yang, Ting Xu, Kai Sheng, Weicheng Lu, Jingdun Xie, Bingzhe Xu · 2024 · Advanced Science
40. Overcoming immune evasion with innovative multi-target approaches for glioblastoma
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41. Identifying new therapeutics for focused ultrasound-enhanced drug delivery in the management of glioblastoma
    Ryan Holman, Nathan Judson McDannold · 2025 · Frontiers in Oncology
42. Application of tumor treating fields for newly diagnosed glioblastoma: understanding of nationwide practice patterns
    Shearwood McClelland, Oluwadamilola M Sosanya, Тимур Митин, Catherine Degnin, Yiyi Chen, Albert A. Attia, John H. Suh, Jerry Jeff Jaboin · 2018 · Journal of Neuro-Oncology
43. Managing Central Nervous System Tumors During Pregnancy
    Na Tosha Gatson · 2022 · CONTINUUM Lifelong Learning in Neurology
44. Therapeutic potential of tumor treating fields for malignant brain tumors
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45. Optune®: Practical Nursing Applications
    Janlyn Murphy, Mary Ellen Bowers, Loretta Barron · 2016 · Clinical journal of oncology nursing
46. BRAF inhibition with concomitant tumor treating fields for a multiply progressive pleomorphic xanthoastrocytoma
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47. Tumor-treating fields as a fourth treating modality for glioblastoma: a meta-analysis
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48. Molecular Evolution of a Glioblastoma Controlled With Tumor Treating Fields and Concomitant Temozolomide
    H. Ian Robins, HuyTram N. Nguyen, Aaron S. Field, Steven Howard, Shahriar M. Salamat, Dustin A. Deming · 2018 · Frontiers in Oncology
49. What is the Role of Tumor-treating Fields in Newly Diagnosed Glioblastoma?
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50. The safety profile of Tumor Treating Fields (TTFields) therapy in glioblastoma patients with ventriculoperitoneal shunts
    Nancy Ann Oberheim-Bush, Wenyin Shi, Michael William McDermott, Alexander Grote, Julia Stindl, Leonardo Lustgarten · 2022 · Journal of Neuro-Oncology
51. The Clinical Application of Tumor Treating Fields Therapy in Glioblastoma
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52. Cancer of the Central Nervous System
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53. Potent in vivo efficacy of oral gallium maltolate in treatment-resistant glioblastoma
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54. Maximizing Local Access to Therapeutic Deliveries in Glioblastoma. Part I: Targeted Cytotoxic Therapy
    Waldemar Debinski, Waldemar Priebe, Stephen B. Tatter · 2017 · Codon Publications eBooks
55. Diffuse intrinsic pontine glioma cells are vulnerable to low intensity electric fields delivered by intratumoral modulation therapy
    Andrew M. Deweyert, Erin Iredale, Hu Xu, Eugene Wong, Susanne Schmid, Matthew O. Hebb · 2019 · Journal of Neuro-Oncology
56. Identification of TNFAIP6 as a hub gene associated with the progression of glioblastoma by weighted gene co‐expression network analysis
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57. Neurosurgical Management of Cerebrospinal Tumors in the Era of Artificial Intelligence : A Scoping Review
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58. Polymer nanocarriers for targeted local delivery of agents in treating brain tumors
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59. Leveraging Metabolomics to Assess the Next Generation of Temozolomide-Based Therapeutic Approaches for Glioblastomas
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60. Tumor treating fields
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61. Modeling Tumor Treating fields (TTFields) application within a realistic human head model
    Cornelia Wenger, Ricardo Salvador, Peter J. Basser, Pedro Cavaleiro Miranda · 2015 · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
62. Amino Acid PET Imaging of the Early Metabolic Response During Tumor-Treating Fields (TTFields) Therapy in Recurrent Glioblastoma
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63. Association between conflict of interest and published position on tumor-treating fields for the treatment of glioblastoma
    Michael J. Hayes, Vinay K. Prasad · 2019 · Journal of Cancer Policy
64. Health-related quality of life and caregiver perspectives in glioblastoma survivors: a mixed-methods study
    Karin Piil, Ib Jarle Christensen, Kirsten Grunnet, Hans Skovgaard Poulsen · 2019 · BMJ Supportive & Palliative Care
65. Water-Content Electrical Property Tomography (wEPT) for Mapping Brain Tissue Conductivity in the 200–1000 kHz Range: Results of an Animal Study
    Cornelia Wenger, Hadas Sara Hershkovich, Catherine Tempel-Brami, Moshe Giladi, Zéev Bomzon · 2019 · Springer eBooks
66. Tumor treating fields for glioblastoma: should it or will it ever be adopted?
    Alissa A. Thomas, Paula K. Rauschkolb · 2019 · Current Opinion in Neurology
67. Disentangling the therapeutic tactics in GBM: From bench to bedside and beyond
    S. Daisy Precilla, Shreyas S. Kuduvalli, T. S. Anitha · 2020 · Cell Biology International
68. Brain Metastases: A Modern Multidisciplinary Approach
    Philip J. O’Halloran, Enrique Gutierrez-Valencia, Aristotelis Kalyvas, Nilesh Mohan, Soha Atallah, Suneil Kumar Kalia, Barbara‐Ann Millar, Normand Laperrière, Tatiana Conrad, Gelareh Mohammed Zadeh et al. · 2020 · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
69. Observations on the anti-glioma potential of electrical fields: is there a role for surgical neuromodulation?
    Ashwin Kumaria · 2021 · British Journal of Neurosurgery
70. Tumour treating fields in glioblastoma: is the treatment tolerable, effective, and practical in UK patients?
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71. Dexamethasone and compliance affect TTFields efficacy to glioblastoma patients: a systematic review and meta-analysis
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72. Tumor growth delay by adjuvant alternating electric fields which appears non-thermally mediated
    Quim Castellví, Mireia Morell, Gabriel Capellá, Antoni Ivorra · 2015 · Bioelectrochemistry
73. Meta-Analysis of Modulated Electro-Hyperthermia and Tumor Treating Fields in the Treatment of Glioblastomas
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74. Local therapy in glioma: An evolving paradigm from history to horizons (Review)
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75. Tumor Treating Fields and Combination Therapy in Management of Brain Oncology
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76. Efficacy and safety of tumor-treating fields in recurrent glioblastoma: a systematic review and meta-analysis
    Xiaohui Li, Zetian Jia, Yaqi Yan · 2022 · Acta Neurochirurgica
77. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Management of Progressive Glioblastoma in Adults: Update of the 2014 Guidelines
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78. Planning system for the optimization of electric field delivery using implanted electrodes for brain tumor control
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79. In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells
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80. Aurora B Kinase Inhibition by AZD1152 Concomitant with Tumor Treating Fields Is Effective in the Treatment of Cultures from Primary and Recurrent Glioblastomas
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81. Alternative magnetic field exposure suppresses tumor growth via metabolic reprogramming
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82. Estimation of TTFields Intensity and Anisotropy with Singular Value Decomposition: A New and Comprehensive Method for Dosimetry of TTFields
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83. A Novel In Vitro Device to Deliver Induced Electromagnetic Fields to Cell and Tissue Cultures
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84. A multi-center prospective study of re-irradiation with bevacizumab and temozolomide in patients with bevacizumab refractory recurrent high-grade gliomas
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85. Transcriptome and single-cell analysis reveal the contribution of immunosuppressive microenvironment for promoting glioblastoma progression
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86. From imaging to biology of glioblastoma: new clinical oncology perspectives to the problem of local recurrence
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87. Tumor-treating fields: time for demystification
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88. Optimization of tumor-treating field therapy for triple-negative breast cancer cells in vitro via frequency modulation
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89. Targeted Alpha Therapy for Glioblastoma: Review on In Vitro, In Vivo and Clinical Trials
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94. The Value of Tumor Treating Fields in Glioblastoma
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95. Comprehensive Commissioning and Clinical Implementation of GammaTiles STaRT for Intracranial Brain Cancer
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97. Survival analysis in high-grade glioma: The role of salvage surgery
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98. Simplified realistic human head model for simulating Tumor Treating Fields (TTFields)
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99. Timing of re-irradiation in recurrent high-grade gliomas: a single institution study
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100. World Cancer Day 2021 - Perspectives in Pediatric and Adult Neuro-Oncology
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