Interleukin-6 signalling: More than Jaks and STATs

Eulenfeld, René, Dittrich, Anna, Khouri, Christina, Müller, Pia J., Mütze, Barbara, Wolf, Alexandra, Schaper, Fred·2012·European Journal of Cell Biology

Cited by (171)

Items 101–171 of 171

  1. IL-6 induces periostin production in human ACL remnants: a possible mechanism causing post-traumatic osteoarthritis
    Tzu-Hao Tseng, Chien‐Lin Chen, Chung-Hsun Chang, Jyh‐Horng Wang, Tai‐Horng Young · 2023 · Journal of Orthopaedic Surgery and Research
  2. Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts
    Tino Stauber, Greta Moschini, Amro A. Hussien, Patrick Klaus Jaeger, Katrien De Bock, Jess Gerrit Snedeker · 2023 · eLife
  3. Impressic acid from Acanthopanax koreanum, possesses matrix metalloproteinase-13 down-regulating capacity and protects cartilage destruction
    Hyun Ae Lim, Dong Suk Min, Han Eul Yun, Kil Tae Kim, Ya Nan Sun, Duc Dat Le, Young Ho Kim, Hyun Pyo Kim · 2017 · Journal of Ethnopharmacology
  4. The length of the interleukin-11 receptor stalk determines its capacity for classic signaling
    Juliane Lokau, Christoph Garbers · 2018 · Journal of Biological Chemistry
  5. Tumor necrosis factor signaling during equine placental infection leads to pro-apoptotic and necroptotic outcomes
    Carleigh Elizabeth Fedorka, Hossam El‐Sheikh Ali, Kirsten E. S. Scoggin, Shavahn C. Loux, Barry A. Ball, Mats H.T. Troedsson · 2022 · Journal of Reproductive Immunology
  6. Inflammation during oocyte maturation reduces developmental competence and increases apoptosis in blastocysts
    Arslan Tariq, Zachary K Seekford, John James Bromfield · 2024 · Biology of Reproduction
  7. Bazedoxifene as a novel strategy for treatment of pancreatic and gastric adenocarcinoma
    Claudia Burkhardt, Léo H. Bühler, Matthieu Tihy, Philippe Morel, M. Forni · 2019 · Oncotarget
  8. Do we need antiplatelet therapy in thrombocytosis? Pro
    Lorenzo Alberio · 2015 · Hämostaseologie
  9. Toxicogenomic evaluation of liver responses induced by acrylamide and glycidamide in male mouse liver
    Dongyan Chen, Huangyou Liu, Enting Wang, Haiyang Yan, Haiqing Ye, Yuan Yuan · 2018 · General Physiology and Biophysics
  10. The biology of interleukin-6 family cytokines is regulated by glycosylation
    Lisa Kohrs, Falk F. R. Buettner, Juliane Lokau, Christoph Garbers · 2025 · Biochemical Journal
  11. Expression of peroxisome proliferator activated receptor (PPAR) genes in porcine endometrium exposed in vitro to IL-6 and INFγ
    Iwona Bogacka, Marek Bogacki, Dorota Boruszewska, Marta Wasielak · 2012 · Reproductive Biology
  12. MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch
    Alexandra Wolf, René Eulenfeld, Hannes Bongartz, Wiebke Hessenkemper, Philip C. Simister, Sam Lievens, Jan H. Tavernier, Stephan M. Feller, Fred Schaper · 2014 · Cellular Signalling
  13. SPECT imaging of interleukin-6 receptor in ovarian tumor xenografts with a novel radiotracer of 99mTc-HYNIC-Aca-LSLITRL
    Fei Li, Zhenzhong Zhang, Teng Cheng, Rui Wei, Yun Dai, Mengqin Lv, Danfeng Luo, Xiaohua Zhu, Ding Ma, Ling Xi et al. · 2015 · Amino Acids
  14. Effects of concomitant glucocorticoids in TOZURA, a common-framework study programme of subcutaneous tocilizumab in rheumatoid arthritis
    E. Choy, R. Caporali, R. Xavier, B. Fautrel, R. Sanmartí, M. Bao, J. Devenport, A. Pethö-Schramm · 2019 · Rheumatology
  15. An Intercellular Flow of Glutathione Regulated by Interleukin 6 Links Astrocytes and the Liver in the Pathophysiology of Amyotrophic Lateral Sclerosis
    Rafael López‐Blanch, Rosario Salvador Palmer, José M. Estrela, Elena Obrador · 2021 · Antioxidants
  16. Thrombopoietic cytokines in patients with hepatitis C virus-associated immune thrombocytopenia
    Cih‐En Huang, Yi-Yang Chen, Jung-Jung Chang, Feng‐Che Kuan, Kuan‐Der Lee, Chang-Hsien Lu, Jrhau Lung, Chien-Heng Shen, Chih‐Cheng Chen · 2016 · Hematology
  17. A Lifelike guided journey through the pathophysiology of pulmonary hypertension—from measured metabolites to the mechanism of action of drugs
    Nathan Weinstein, Jørn Carlsen, Sebastian Schulz, Timothy Stapleton, H Henriksen, Evelyn Travnik, Pär I. Johansson · 2024 · Frontiers in Cardiovascular Medicine
  18. Rapamycin-Sensitive Late-LTP is Enhanced in the Hippocampus of IL-6 Transgenic Mice
    Anneke H. O. Olde Engberink, Ruben V. Hernandez, Pierre N. E. De Graan, Donna L. Gruol · 2017 · Neuroscience
  19. Split2 Protein-Ligation Generates Active IL-6-Type Hyper-Cytokines from Inactive Precursors
    Jens M. Moll, Melanie Wehmöller, Nils C. Frank, Lisa Homey, Paul Baran, Christoph Garbers, Larissa Lamertz, Jonathan H. Axelrod, Eithan Galun, Henning D. Mootz et al. · 2017 · ACS Synthetic Biology
  20. Glioblastoma invasion factor ODZ1 is induced by microenvironmental signals through activation of a Stat3-dependent transcriptional pathway
    Verónica Vidal, Olga Gutierrez, Ana Talamillo, Carlos Velásquez, José L. Fernández-Luna · 2021 · Scientific Reports
  21. Non‐canonical STAT3 function reduces REDD1 transcription
    Nadine Köhler, Nicole Wundrack, Svenja Schulz, Florian Bartonitz, Fred Schaper, Anna Dittrich · 2022 · FEBS Journal
  22. Rhizoma Dioscoreae Extract Protects against Alveolar Bone Loss in Ovariectomized Rats via microRNAs Regulation
    Zhiguo Zhang, Changheng Song, Fangzhen Zhang, Lihua Xiang, Yanjing Chen, Yan Li, Jinghua Pan, Hong Liu, Gary Guishan Xiao, Dahong Ju · 2015 · Nutrients
  23. VERU-111, an orally available tubulin inhibitor, suppresses ovarian tumor growth and metastasis
    Shelby Waddell, Guannan Zhao, Ziping Liu, Hao Chen, Wenjing Zhang, Yaohong Wang, Duane D. Miller, Junming Yue, Wěi Li · 2024 · Journal of Pharmacology and Experimental Therapeutics
  24. Human Recombinant Interleukin-6 and Leukemia Inhibitory Factor Improve Inner Cell Mass Cell Number but Lack Cryoprotective Activities on In Vitro-Produced Bovine Blastocysts
    Mary A. Oliver, Kayla J. Alward, M.L. Rhoads, Alan D. Ealy · 2025 · Animals
  25. Platelet Glycobiology and the Control of Platelet Function and Lifespan
    Silvia Giannini, Hervé Falet, Karin M. Hoffmeister · 2019 · Elsevier eBooks
  26. The interleukin-6 trans-signaling promotes progesterone production in human granulosa-lutein cells
    Saijiao Li, Hsun‐Ming Chang, Jeremy H Wang, Jing Yang, Peter C. K. Leung · 2022 · Biology of Reproduction
  27. Interferon-related gene expression in response to TNF inhibitor treatment in ankylosing spondylitis patients: a pilot study
    Stephanie Rose Harrison, Agata N. Burska, Paul Emery, Helena Marzo‐Ortega, Frédérique Ponchel · 2020 · Lara D. Veeken
  28. Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic Consequences of Maternal Obesity in Male Offspring
    Saida Breuer, Philipp Kasper, Christina Vohlen, Ruth Janoschek, Thorben Hoffmann, Sarah Appel, Elena Müller-Limberger, Andrea Mesaros, Stefan Rose‐John, Christoph Garbers et al. · 2021 · Nutrients
  29. Modifications pharmacocinétiques liées à une infection aiguë. Exemples issus de la pandémie de SARS-CoV-2
    Anaëlle Chavant, Elodie Gautier‐Veyret, Stéphanie Chhun, Romain Guilhaumou, Françoise Stanke‐Labesque · 2020 · Therapies
  30. ABSTRACTS FROM THE 10 TH INTERNATIONAL ISSX MEETING
    2014 · Drug Metabolism Reviews
  31. Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts
    Tino Stauber, Greta Moschini, Amro A. Hussien, Patrick Klaus Jaeger, Katrien De Bock, Jess Gerrit Snedeker · 2025 · eLife
  32. Therapie der Uveitis mit Biologika
    Vita Louisa Sophie Dingerkus, Matthias Dieter Becker, Deshka Doycheva · 2022 · Klinische Monatsblätter für Augenheilkunde
  33. IL-6 Responsiveness of CD4+ and CD8+ T Cells after Allogeneic Stem Cell Transplantation Differs between Patients and Is Associated with Previous Acute Graft versus Host Disease and Pretransplant Antithymocyte Globulin Therapy
    Tor Henrik Anderson Tvedt, Stefan Rose‐John, Galina Tsykunova, Aymen Bushra Ahmed, Tobias Gedde‐Dahl, Elisabeth Ersvær, Øystein Bruserud · 2022 · Journal of Clinical Medicine
  34. Investigating plasticity within the interleukin-6 family with AlphaFold-Multimer
    Stefan Düsterhöft, Johannes N. Greve, Christoph Garbers · 2025 · Computational and Structural Biotechnology Journal
  35. A novel infrapatellar fat pad preservation technique in anterior cruciate ligament reconstruction reduces postoperative pain and cartilage damage: a retrospective study
    Shilin Li, Mingfeng Lu, Lilian Zhao, Lilei He, Weifeng Fan, Jie Zhou, Sumin Yan · 2025 · Journal of Orthopaedic Surgery and Research
  36. Role of Interleukin-6 in Type 1 Diabetes Mellitus (Review of Articles)
    Ikram Khazal Al-Hasso · 2023 · Annals of the College of Medicine Mosul/Annals of the College of Medecine
  37. Dysregulated Gab1 signalling in triple negative breast cancer
    Hannes Bongartz, Nora Mehwald, Elena A. Seiß, Tim Schumertl, Norbert Naß, Anna Dittrich · 2024 · Cell Communication and Signaling
  38. The interleukin-6 signal transducer receptor subunit is required for optimal in vitro bovine embryo development
    Savannah L. Speckhart, Abigayle B Pollock, Kayla J. Alward, Kayla Farrell, Mary A. Oliver, Kiho Lee, Fernando H. Biase, Alan D. Ealy · 2025 · Biology of Reproduction
  39. In vivo effect of acute exposure to interleukin-6 on the developing visual system
    Grasielle Duarte Menezes, Adriana da Cunha Faria‐Melibeu, Claudio Alberto Serfaty, Paula Campello‐Costa · 2019 · Neuroscience Letters
  40. Cytokines, Chemokines, and the Innate Immune System in Sjögren’s Syndrome
    Silke Appel, Roland Jonsson · 2016 · Elsevier eBooks
  41. Computational analysis of IL-6/IL-22 signaling in liver disease
    Marcus Keßler, Lara Klemt, Marius Kirchner, Jörg Ackermann, Heiko Mühl, Christoph Welsch, Ina Koch · 2025 · Biosystems
  42. Ca 2+ , ROS, IL-6, and p38 MAPK signaling loops underlying alterations in myotube formation induced by a severe MH/CCD mutation in RyR1
    Maikel Valle-Clara, Guillermo Ávila · 2025 · American Journal of Physiology-Cell Physiology
  43. Correlation Between Interleukin IL-6/IL-6 Receptor Polymorphisms (IL6–174C>G and IL6R 1073A>C) and RAS/BRAF Mutations in Patients with Colorectal Cancer
    Ekaterina Smagina, Dar’ya Polit’ko, Vadim Vladimirovich Kumeiko, Lyudmila Gurina, Anna M. Stenkova · 2025 · Gastroenterology Insights
  44. SOCS3 limits endotoxin-induced endothelial dysfunction by blocking a required autocrine interleukin 6 signal in human umbilical vein endothelial cells
    Nina Martino, Ramon Bossardi Ramos, Dareen S. Chuy, Lindsay Tomaszek, Alejandro Pablo Adam · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  45. IL-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating progenitor proliferation & migration to damage
    Tino Stauber, Greta Moschini, Amro A. Hussien, Patrick Klaus Jaeger, Katrien De Bock, Jess Gerrit Snedeker · 2023 · eLife
  46. Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts
    Tino Stauber, Greta Moschini, Amro A. Hussien, Patrick Klaus Jaeger, Katrien De Bock, Jess Gerrit Snedeker · 2024 · eLife
  47. Study of the capacity of Toll-like receptors to modulate pro-inflammatory responses mediated by receptors for the complement anaphylatoxin C5a
    Benjamin Holst · 2013 · ORCA Online Research @Cardiff (Cardiff University)
  48. The regulation of gp130 surface expression on monocytes : implications in chronic inflammation
    Nora Honke, P Idm, Rainer Fischer, Klaus Tenbrock · 2014 · RWTH Publications (RWTH Aachen)
  49. Mechanisms of clearance to control the fate of platelets
    Hiroshi Saitoh, Tsukasa Ohmori · 2016 · Japanese Journal of Thrombosis and Hemostasis
  50. Papel da interleucina 6 (IL-6) na resposta inflamatória neutrofílica durante a infecção por Leishmania infantum>
    Ítala Cristine Silva · 2017
  51. Efeito da ghrelina sobre o eixo GH/IGF-1 em animais submetidos à endotoxemia
    Felipe de Lima Faim · 2018
  52. The immunological and vascular effects of IL-6 signalling in transplant arteriosclerosis
    Ashani Montgomery · 2019 · Summit (Simon Fraser University)
  53. The Regulated Expression of Focal Adhesion Kinase (FAK) Family Kinases Modulates Mononuclear Phagocyte Differentiation, Migration, and Breast Tumor Progression
    Michael F. Gutknecht · 2013
  54. Supplementing Bovine Embryo Culture Media to Improve the Production and Quality of In Vitro Produced Bovine Embryos
    Lydia K. Wooldridge · 2020 · VTechWorks (Virginia Tech)
  55. Klinischer Nutzen von Tocilizumab und anderen immunmodulatorischen Substanzen bei COVID-19
    Daniel Hornuß, Roland Giesen, Paul Marc Biever, Winfried V. Kern · 2021 · DMW - Deutsche Medizinische Wochenschrift
  56. Janus kinase 1 drives endoplasmic reticulum stress-induced transcriptional reprogramming in astrocytes
    Savannah G. Sims · 2021
  57. ELUCIDATION OF THE ROLE OF AGOUTI-SIGNALING PROTEIN THROUGHOUT FOLLICULOGENESIS AND EARLY EMBRYONIC DEVELOPMENT IN CATTLE
    Heather L Chaney · 2023
  58. Zip-14 Expression After Abdominal Surgery in Rats is Mainly Regulated by the Il-6 Signaling Pathway
    Violeta Aburto-Luna, Gerardo Santos‐López, Samuel Treviño, Bertha Alicia León Chávez, Eduardo Brambila · 2023 · Research Square
  59. Petri net model of coupled IL-6 and IL-22 pathways supports the understanding of pharmacological effects of cytokine variants
    Marcus Keßler, Lara Klemt, Jörg Ackermann, Heiko Mühl, Christoph Welsch, Ina Koch · 2024
  60. No evidence for paradoxical effects of tocilizumab in rodents
    Christoph Garbers · 2025 · Naunyn-Schmiedeberg s Archives of Pharmacology
  61. Biomechanical, biological, and molecular mechanisms of tendon homeostasis, adaptation, repair, and disease
    Tino Stauber, Jess Gerrit Snedeker · 2025 · Elsevier eBooks
  62. Additional file 2 of The tyrosine phosphatase SHP2 increases robustness and information transfer within IL-6-induced JAK/STAT signalling
    Jessica Fiebelkow, André Guendel, Beate Guendel, Nora Mehwald, Jetka, Tomasz, Michał Komorowski, Steffen Waldherr, Fred Schaper, Anna Dittrich · 2021 · Figshare
  63. Les astrocytes réactifs, des partenaires anti-agrégants dans la maladie de Huntington : identification des mécanismes impliqués dans le dialogue neurone-astrocyte
    Laurene Abjean · 2019 · theses.fr (ABES)
  64. Investigating the molecular signature of reactive astrocytes mediated by the JAK2- STAT3 pathway using different omics : transcriptomics and proteomics insights
    Miriam Riquelme‐Perez · 2023 · theses.fr (ABES)
  65. Décryptage des modifications précoces du phosphoprotéome en réponse à BMP9 et BMP10 dans les cellules endothéliales
    Mohammad Al Tarrass · 2023 · theses.fr (ABES)
  66. Loss of cold shock domain-containing protein E1 (CSDE1) function enhances mRNA stability of interleukin-6 and promotes malignant transformation in endometrial cancer cells
    Y Y Liu, Lianqiao Qiao, Xiaoli Wen, Mengfei Wang, Junyuan Li, Yan Ding, Han Tao, Yilin Dai, Luhui Wang, Kun Gao et al. · 2026 · Cell Communication and Signaling
  67. The role of interleukin-6 receptor in cardiovascular and cerebrovascular diseases
    Junkai Zou, Zhanyu Wang, Minghui Jiang, Yuan Yang, Rong Liu, Jianping Wu, Hao Li, Yongjun Wang, Si Cheng · 2026 · The Innovation Medicine
  68. Age-associated inflammation is accompanied by JAK1–STAT1 signaling activation, megakaryocyte apoptosis, and enhanced thrombopoiesis in naturally aged mice
    Yixuan Xu, 谢双锋, Fang He, Fenglin Song, Yu-Heng Mao, Ruijie Wang, Heyu Ni, Yan Yang · 2026 · Experimental Gerontology
  69. Exercise-Induced Skeletal Muscle Secretory Factors and Macrophage Functional Remodeling: Mechanistic Advances
    Zi-Yang Li, Chen-Yu Lin, Lin-Tao Tang, Yi-Yao Xu, Jie-Ming Liang, De-Hui Pan, Zi-Shuai Huang, Xian-Yan Xie, Yu Wang, Shu-Qi Qin et al. · 2026 · International Journal of Molecular Sciences
  70. Intrinsic IL-6 expression reduces rhIL-6-induced JAK/STAT activation and promotes glucose and oleic acid oxidation in cultured human myoblasts
    Anja Srpčič, Katarina Miš, Barbara Žvar Baškovič Gantar, Klemen Dolinar, Ulrik Nygaard Mjaaseth, Arild Christian Rustan, Eili Tranheim Kase, Katja Lakota, Katja Perdan Pirkmajer, Sergej Pirkmajer · 2026 · American Journal of Physiology-Cell Physiology
  71. Selective inhibition of IL-6 trans-signalling reveals distinct mechanisms of human classic and trans-signalling receptor-complex formation
    Emelie Rieneck, Jan René Haak, Kamal Asgarov, Jean‐René Pallandre, Nicole Wundrack, Julia Ettich, Niloufarsadat Miri, Doreen Manuela Floss, Jürgen Scheller, Christoph Garbers et al. · 2026 · Communications Biology