Therapeutic effects of mangiferin on sepsis-associated acute lung and kidney injuries via the downregulation of vascular permeability and protection of inflammatory and oxidative damages

Zhang, Dong; Han, Shasha; Zhou, Yue; Qi, Boyang; Wang, Xiaozhi

doi:10.1016/j.ejps.2020.105400

Therapeutic effects of mangiferin on sepsis-associated acute lung and kidney injuries via the downregulation of vascular permeability and protection of inflammatory and oxidative damages

Background Sepsis is a serious systemic inflammatory response that primarily affects the lungs and kidneys. Moreover, a few drugs can effectively treat this disease. Mangiferin (MF) is a xanthone glucoside that possesses many pharmacological effects. This study aims to assess the effects of MF on…