The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
The effects of disease severity, use of corticosteroids and social factors on neuropsychiatric complaints in severe acute respiratory syndrome (SARS) patients at acute and convalescent phases
Open accessAbstract
Objective: To evaluate the effects of disease severity, corticosteroids and social factors on neuropsychiatric complaints in severe acute respiratory syndrome (SARS) patients, both during acute and convalescent phases. Methods: Self-administered mail questionnaires survey to 308 SARS patients after discharging from hospital. Both patients and their families were asked about symptoms related to various neuropsychiatric domains, and the questions covered both acute and convalescent phases. Results: Among the 102 (33%) valid replies, 65% had strong symptoms in convalescent phase as indicated by GHQ28 score ≥ 5. In multiple linear regression analysis, use of pulse steroid and total dosages of pulse steroid during hospitalisation were predictive for anxiety-depression, psychosis and behavioural symptoms in acute phase, the effects persisted in convalescent phase. Disease severity had direct correlation with symptoms in all neuropsychiatric domains at acute phase and anxiety-depression and cognition at convalescent phase. Health care workers had more neuropsychiatric complaints in both phases. Severity of symptoms, corticosteroids and social factors explained about half of the variances (R2 = 52) in anxiety-depression at acute phase and 33% at convalescent phase. Conclusions: Severe disease, high dose corticosteroids and being health care workers were independent predictors of neuropsychiatric complaints in both acute and convalescent phases.
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“Our findings mirror the results from previous coronaviruses outbreak studies, where the psychiatric morbidities ranged from 10% to 35% in the post-illness stage (Rogers et al., 2020, Sheng et al., 2005).”
From Anxiety and depression in COVID-19 survivors: role of inflammatory and clinical predictors (2020) · cites this paper as Sheng et al., 2005
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“In SARS and MERS, after recovery from the infection, impairment of memory, attention, concentration, or mental processing speed were reported in more than 15% of patients at a follow-up period ranging between 6 weeks and 39 months (Hopkins et al., 1999, Sheng et al., 2005).”
From Persistent psychopathology and neurocognitive impairment in COVID-19 survivors: effect of inflammatory biomarkers at three-month follow-up (2021) · cites this paper as Sheng et al., 2005
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Rogers, J. P., Chesney, E., Oliver, D., Pollak, T. A., McGuire, P., Fusar-Poli, P., Zandi, M. S., Lewis, G., & David, A. S. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(20)30203-0 · Cited by 2,407
Anxiety and depression in COVID-19 survivors: role of inflammatory and clinical predictors
Mazza, M. G., De Lorenzo, R., Conte, C., Poletti, S., Vai, B., Bollettini, I., Melloni, E. M. T., Furlan, R., Ciceri, F., Rovere-Querini, P., et al. (2020) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2020.07.037 · Cited by 1,804
Long-term psychiatric morbidities among SARS survivors
Mak, I. W. C., Chu, C. M., Pan, P. C., Yiu, M. G. C., & Chan, V. L. (2009) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2009.03.001 · Cited by 1,018
Lam, M. H.-B. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.384 · Cited by 723
Mazza, M. G., Palladini, M., De Lorenzo, R., Magnaghi, C., Poletti, S., Furlan, R., Ciceri, F., Rovere-Querini, P., & Benedetti, F. (2021) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2021.02.021 · Cited by 513
“In SARS and MERS, after recovery from the infection, impairment of memory, attention, concentration, or mental processing speed were reported in more than 15% of patients at a followup period ranging between 6 weeks and 39 months (Hopkins et al., 1999; Sheng et al., 2005).”
Metadata
- Authors
- Sheng, B., Wing Cheng, S. K., Lau, K. K., Li, H. L., & Yiu Chan, E. L.
- Affiliations
- Princess Margaret Hospital (HK)
- Corresponding author
- Sheng, Bun
- ORCID
- Sheng, Bun
- Venue
- European Psychiatry
- Publisher
- Cambridge University Press (CUP)
- Published
- 2005-05
- Volume
- 20
- Issue
- 3
- Pages
- 236-242
- ISSN
- 0924-9338 (ISSN-L)
- 1778-3585
- PMC
- PMC7135192
- OpenAlex
- W1965607682
- Cited by
- 117
- References
- 28
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 4 · 2023: 9 · 2022: 22 · 2021: 27 · 2020: 36 · 2019: 1 · 2014: 1 · 2013: 1
- FWCI
- 1.61
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Psychiatry (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Keywords
- SARS, neuropsychiatric symptoms, corticosteroids, disease severity, convalescence, anxiety and depression, psychosis, behavioural symptoms, cognitive impairment, healthcare workers, post-discharge outcomes, social factors
- MeSH terms
- Adult, Anti-Inflammatory Agents, Anxiety Disorders, Bipolar Disorder, Cognition Disorders, Convalescence, Demography, Factor Analysis, Statistical, Female, Health Personnel, Health Status, Humans, Male, Psychotic Disorders, Surveys and Questionnaires, Severity of Illness Index, Severe Acute Respiratory Syndrome
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