CoChat
Sign Up
Cited by 1,223Sexual function and dysfunction studiesUrological Disorders and TreatmentsSexuality, Behavior, and Technology

The DOI matches its Crossref record; 241 of the 241 references it cites were found in a registry or an index.

Guidelines on Male Sexual Dysfunction: Erectile Dysfunction and Premature Ejaculation

Hatzimouratidis, Konstantinos, Amar, Edouard, Eardley, Ian, Giuliano, Francois, Hatzichristou, Dimitrios, Montorsi, Francesco, Vardi, Yoram, Wespes, Eric·2010·European Urology
DOI 10.1016/j.eururo.2010.02.020
Open this paper in CoChat — free account

Abstract

Context Erectile dysfunction (ED) and premature ejaculation (PE) are the two most prevalent male sexual dysfunctions.Objective To present the updated version of 2009 European Association of Urology (EAU) guidelines on ED and PE.Evidence acquisition A systematic review of the recent literature on the epidemiology, diagnosis, and treatment of ED and PE was performed. Levels of evidence and grades of recommendation were assigned.Evidence synthesis ED is highly prevalent, and 5-20% of men have moderate to severe ED. ED shares common risk factors with cardiovascular disease. Diagnosis is based on medical and sexual history, including validated questionnaires. Physical examination and laboratory testing must be tailored to the patient's complaints and risk factors. Treatment is based on phosphodiesterase type 5 inhibitors (PDE5-Is), including sildenafil, tadalafil, and vardenafil. PDE5-Is have high efficacy and safety rates, even in difficult-to-treat populations such as patients with diabetes mellitus. Treatment options for patients who do not respond to PDE5-Is or for whom PDE5-Is are contraindicated include intracavernous injections, intraurethral alprostadil, vacuum constriction devices, or implantation of a penile prosthesis. PE has prevalence rates of 20-30%. PE may be classified as lifelong (primary) or acquired (secondary). Diagnosis is based on medical and sexual history assessing intravaginal ejaculatory latency time, perceived control, distress, and interpersonal difficulty related to the ejaculatory dysfunction. Physical examination and laboratory testing may be needed in selected patients only. Pharmacotherapy is the basis of treatment in lifelong PE, including daily dosing of selective serotonin reuptake inhibitors and topical anaesthetics. Dapoxetine is the only drug approved for the on-demand treatment of PE in Europe. Behavioural techniques may be efficacious as a monotherapy or in combination with pharmacotherapy. Recurrence is likely to occur after treatment withdrawal.Conclusions These EAU guidelines summarise the present information on ED and PE. The extended version of the guidelines is available at the EAU Web site (http://www.uroweb.org/nc/professional-resources/guidelines/online/).

Overview

Integrity signals

Registry

Crossref · 10.1016/j.eururo.2010.02.020

Cites

241 of 241 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

1 retracted

Show all 240 references

Cited by

Sorted by citations

Items 201–300 of 1,000

Related

See all

Metadata

Authors
Hatzimouratidis, K., Amar, E., Eardley, I., Giuliano, F., Hatzichristou, D., Montorsi, F., Vardi, Y., & Wespes, E.
Affiliations
  • Hôpital Bichat-Claude-Bernard (FR)
  • Assistance Publique – Hôpitaux de Paris (FR)
  • Aristotle University of Thessaloniki (GR)
  • Vita-Salute San Raffaele University (IT)
  • Technion – Israel Institute of Technology (IL)
  • Erasmus Hospital (BE)
ORCID
Venue
European Urology
Publisher
Elsevier BV
Published
2010-05
Volume
57
Issue
5
Pages
804-814
ISSN
0302-2838 (ISSN-L)
DOI
10.1016/j.eururo.2010.02.020
OpenAlex
W2128056532
Cited by
1,223
References
240
Citations by year
2026: 32 · 2025: 35 · 2024: 42 · 2023: 50 · 2022: 52 · 2021: 84 · 2020: 83 · 2019: 83 · 2018: 72 · 2017: 108 · 2016: 114 · 2015: 98 · 2014: 106 · 2013: 88 · 2012: 94
FWCI
56.49
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • European Urology (publishedVersion)
  • PubMed (publishedVersion)
  • Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
  • Health Sciences › Medicine › Urology › Urological Disorders and Treatments
  • Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
Keywords
erectile dysfunction, premature ejaculation, male sexual dysfunction, phosphodiesterase-5 inhibitors, sildenafil, tadalafil, vardenafil, intracavernous injection, vacuum constriction devices, penile prosthesis, selective serotonin reuptake inhibitors, topical anesthetics, dapoxetine, behavioural techniques, diagnosis, treatment, prevalence, risk factors, diabetes mellitus
MeSH terms
Algorithms, Decision Trees, Ejaculation, Humans, Erectile Dysfunction, Male, Sexual Dysfunction, Physiological, Time Factors

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review