Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis

Dedeoglu, Alpaslan, Cormier, Kerry, Payton, Sandra, Tseitlin, Katya A., Kremsky, Jonathan N., Lai, Li, Li, Xiaohua, Moir, Robert D. +5 more·2004·Experimental Gerontology

Cited by (141)

Items 101–141 of 141

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  4. Why nutraceuticals do not prevent or treat Alzheimer's disease
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  6. Combining conformational sampling and selection to identify the binding mode of zinc-bound amyloid peptides with bifunctional molecules
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  8. 1-(2-Hydroxyethoxy)Methyl-2-Methyl-3-Hydroxyl-4-Pyridinone: ATargeted, Bifunctional Chelating Agent for Potential Uranic Detoxification in the Kidney
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  11. Cutting-edge Patents in Alzheimers Disease Drug Discovery: Anticipation of Potential Future Treatments
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  12. Ligand Design to Target and Modulate Metal–Protein Interactions in Neurodegenerative Diseases
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  13. Design and Applications of Bifunctional Small Molecules in Biology
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  14. Plasma and CSF Abeta for the longitudinal prediction of Alzheimer's disease dementia and other dementias in people with cognitive decline but no dementia
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  15. A Multifunctional Biocompatible Drug Candidate is Highly Effective in Delaying Pathological Signs of Alzheimer’s Disease in 5XFAD Mice
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  16. Sialic Acid Hydroxamate: A Potential Antioxidant and Inhibitor of Metal‐Induced β‐Amyloid Aggregates
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  17. Metabolism of copper and possibilities for its regulation
    Peep Palumaa · 2023 · Proceedings of the Estonian Academy of Sciences
  18. Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.
    Willam T Wang, Breeya A Tailor, David S Cohen, Xudong Huang · 2019 · PubMed
  19. The Essentiality of Iron Chelation in Neuroprotection
    Hailin Zheng, Silvia A. Mandel, Tamar Amit, Moussa B. H. Youdim, Orly Weinreb · 2005 · Oxidative stress and disease
  20. Maladies neurodégénératives et stress oxydant
    Elise Lévy · 2020 · theses.fr (ABES)
  21. Progress in the development of new drugs in Alzheimer’s disease
    Antoine Piau, Fati Nourhashémi, Christophe Hein, Céline Caillaud, Bruno J. Vellas · 2010 · The journal of nutrition health & aging
  22. Plasma and Cerebro Spinal Fluid Amyloid Beta 42, 40 and the 42:40 ratio for diagnosis of incipient Dementia in a population with objective cognitive decline.
    Craig William Ritchie, Colin Louis Masters, Sam Mason, Qiao‐Xin Li, Rupert H. McShane · 2010 · Cochrane Database of Systematic Reviews
  23. Metal Chelators as a Potential Therapeutic Agent for Alzheimer’s Disease
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    Bin Sun, Heyan Jiang · 2024 · Journal of Inorganic Biochemistry
  25. Nouvelles thérapeutiques dans la maladie d’Alzheimer: vers un traitement visant à ralentir la progression de la maladie
    Antoine Piau, Christophe Hein, Fati Nourhashémi, Bruno J. Vellas · 2009 · Les cahiers de l année gérontologique
  26. Deciphering the Significance of Metal Ions in the Pathogenesis of Alzheimer's Disease and Forging Pathways Towards Prospective Therapeutic Strategies
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  27. Metals Involvement in Alzheimer’s Disease Pathogenesis
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  28. An Overview of Multifunctional Metal Chelators as Potential Treatments for Neurodegenerative Diseases
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  29. Drug Development and Alzheimer's Disease
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  30. Development of nano-scale and biomimetic surfaces for biomedical applications
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  31. PHYSICO-CHEMICAL OPTIMIZATION AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES OF ALDEHYDE-DERIVED N-ACYLHYDRAZONES: TOWARDS THE IMPROVEMENT OF MODERATE METAL CHELATORS AS A STRATEGY AGAINST METAL-ENHANCED AGGREGOPATHIES
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  32. Interaction entre le zinc(II) et le peptide amyloïde bêta lié à la maladie d'Alzheimer
    Christine Talmard · 2007
  33. Novel regulation of neuronal genes implicated in Alzheimer disease by microRNA
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  34. Iron and Monoamine Oxidase in Brain Function and Dysfunction
    Moussa B. H. Youdim, Orly Weinreb, Silvia A. Mandel, Tamar Amit · 2009 · Oxidative stress and disease
  35. Técnicas computacionais aplicadas a uma série de antagonistas do receptor 5-HT>sub<6>/sub< - potencial alvo para a doença de Alzheimer
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  36. Synthesis and Characterization of Second- Generation Iron Pro-chelators
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  37. Drug development and Alzheimer's disease
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  38. Plasma and Cerebro Spinal Fluid Amyloid Beta 42, 40 and the 42:40 ratio for diagnosis of incipient Dementia in a population with objective cognitive decline.
    Craig William Ritchie, Colin Louis Masters, Sam Mason, Qiao‐Xin Li, Rupert H. McShane · 2010 · Cochrane Database of Systematic Reviews
  39. Metallic Mysteries: Deciphering Their Contribution to Alzheimer’s Pathogenesis
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  40. Generation of oxidative stress as an anticancer therapeutic strategy : Investigating the mechanism of action of vitamin C, auranofin and their combination
    Nadine El Banna · 2019
  41. BindingDB Entry 50038080: Multi-target-directed ligands to combat neurodegenerative diseases.
    BindingDB · 2012 · UC San Diego