An approach for the extract generation and toxicological assessment of tobacco-free ‘modern’ oral nicotine pouches
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In vitro studies indicate that extracts from nicotine pouches are significantly less biologically active than extracts from Swedish snus or cigarette smoke.
“In vitro studies also indicate that extracts from NPs are significantly less biologically active than extracts from Swedish snus or cigarette smoke [22], supporting a potential role of NPs in tobacco harm reduction.”
From A Randomised Study to Investigate the Nicotine Pharmacokinetics of Oral Nicotine Pouches and a Combustible Cigarette (2022) · cites this paper as [22]
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Research works printed but not linked: 3
- Ke, N., Wang, X., Xu, X., Abassi, Y.A., 2011. The xcelligence system for real-time and label-free monitoring of cell viability. In: Stoddart, M.J. (Ed.), Mammalian Cell Viability: Methods and Protocols. Humana Press, Totowa, Nj.
- Lee, P.N., 2013. Epidemiological evidence relating snus to health-an updated review based on recent publications. Harm Reduct. J. 10, 36.
- Nrc, 2007. Toxicity Testing in the 21st Centry: A Vision and Strategy. National Academic Press. Oecd, 2019. Test No. 432: in Vitro 3t3 NRU Phototoxicity Test.
Cited by
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McEwan, M., Azzopardi, D., Gale, N., Camacho, O. M., Hardie, G., Fearon, I. M., & Murphy, J. (2022) · European Journal of Drug Metabolism and Pharmacokinetics · doi:10.1007/s13318-021-00742-9 · Cited by 70 · see citing works
Kopa-Stojak, P. N., & Pawliczak, R. (2026) · Exposure and Health · doi:10.1007/s12403-026-00812-w
- Authors
- E, B., N, E., S, B., S, S., D, S., M, T., S, M., A, B., D, B., D, T., & M, G.
- Venue
- Food and Chemical Toxicology
- Publisher
- Elsevier BV
- Published
- 2020-11
- Volume
- 145
- Pages
- 111713
- ISSN
- 0278-6915
- Cited by
- 39
- References
- 0
- Language
- en
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