Nek7 kinase is enriched at the centrosome, and is required for proper spindle assembly and mitotic progression

Yissachar, Nissan; Salem, Hagit; Tennenbaum, Tamar; Motro, Benny

doi:10.1016/j.febslet.2006.10.069

Nek7 kinase is enriched at the centrosome, and is required for proper spindle assembly and mitotic progression

Members of the NIMA-related kinases (NRK) family are recently emerging as central regulators of various aspects of the cell cycle. However, the cellular roles of the mammalian NRK, Nek7, remain obscure. We show here that the endogenous Nek7 protein is enriched at the centrosome in a microtubule-i…