Roles of LIM kinases in central nervous system function and dysfunction
Open accessAbstract
We finally present the existence of a cofilin‐independent pathway also involved in neuronal function. A better understanding of the differences between both LIMKs and of the precise molecular mechanisms involved in their mode of action and regulation is now required to improve our understanding of the physiopathology of the neuronal diseases associated with LIMKs.
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SSH2 carries two HHMCs and might be involved in neurite outgrowth.
“SSH2 (two HHMCs) might be involved in neurite outgrowth99.”
From A catalog of single nucleotide changes distinguishing modern humans from archaic hominins (2019) · cites this paper as [99]
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References 175 · Cited by 54
- Authors
- Cuberos, H., Vallée, B., Vourc'h, P., Tastet, J., Andres, C. R., & Bénédetti, H.
- Affiliations
- Université de Tours (FR)
- Centre National de la Recherche Scientifique (FR)
- University Medical Center Utrecht (NL)
- Corresponding author
- Cuberos, H.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2015-11-03
- Volume
- 589
- Issue
- 24PartB
- Pages
- 3795-3806
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2143519804
- Cited by
- 54
- References
- 175
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 6 · 2023: 3 · 2022: 4 · 2021: 8 · 2020: 6 · 2019: 4 · 2018: 4 · 2017: 7 · 2016: 3
- FWCI
- 0.45
- Type
- journal article
- Language
- en
- Open access
- green
- dspace.library.uu.nl
- Licence
- Locations
- FEBS Letters (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Funders
- Région Centre
- Ligue Contre le Cancer
- Centre National de la Recherche Scientifique
- Institut National de la Santé et de la Recherche Médicale
- Université François Rabelais de Tours
- Ministère de l’Enseignement Supérieur et de la Recherche
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Keywords
- LIM kinase 1, LIM kinase 2, cofilin phosphorylation, actin dynamics, brain development, synaptic plasticity, neuronal diseases, central nervous system
- MeSH terms
- Animals, Central Nervous System, Central Nervous System Diseases, Humans, Neurons, Lim Kinases
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