Matrix metalloproteinases are elevated in the urine of patients with endometriosis
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In a prospective, blinded, longitudinal study MMP-2, MMP-9, and MMP-9/neutrophil gelatinase-associated lipocalin were significantly more likely to be detected in the urine of patients with endometriosis than in controls.
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A panel consisting of MMP-2, MMP-9, and MMP-9/neutrophil gelatinase-associated lipocalin is significantly elevated in women with endometriosis relative to controls.
“A panel consisting of MMP-2, MMP-9, and MMP-9/neutrophil gealtinase-associated lipocalin was significantly elevated in a cohort of 33 women with endometriosis relative to expression in a group of 13 controls [104].”
From Update on biomarkers for the detection of endometriosis (2015) · cites this paper as [104]
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References 29 · Cited by 40
- Authors
- Becker, C. M., Louis, G., Exarhopoulos, A., Mechsner, S., Ebert, A. D., Zurakowski, D., & Moses, M. A.
- Affiliations
- Boston Children's Hospital (US)
- Charité – Universitätsmedizin Berlin (DE)
- Corresponding author
- Becker, Christian M.
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2010-11
- Volume
- 94
- Issue
- 6
- Pages
- 2343-2346
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2080505512
- Cited by
- 40
- References
- 29
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 4 · 2020: 1 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 2 · 2015: 5 · 2014: 3 · 2013: 4 · 2012: 4
- FWCI
- 4.17
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute for Health and Care Research
- National Institutes of Health
- Medical Research Council (G0601458)
- National Cancer Institute (1 RO1 CA118764-01, R01CA118764, P01CA045548)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Protease and Inhibitor Mechanisms
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Keywords
- matrix metalloproteinases, endometriosis, urinary biomarkers, MMP-2, MMP-9, neutrophil gelatinase-associated lipocalin, biomarker detection
- MeSH terms
- Adult, Endometriosis, Female, Humans, Uterine Diseases, Biomarkers, Up-Regulation, Case-Control Studies, Matrix Metalloproteinase 2, Matrix Metalloproteinase 9, Matrix Metalloproteinases
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