Complications during pregnancy and delivery in women with untreated rectovaginal deep infiltrating endometriosis
Open accessAbstract
Objective To study outcomes and complications during pregnancy and at delivery in women with a posterior deep infiltrating endometriosis (DIE) nodule persisting after surgery and diagnosed at transvaginal sonography (TVS) in comparison with a control group of women without endometriosis.Design Multicenter observational and cohort study.Setting University hospital.Patient(s) Women (n = 200) with a posterior DIE nodule equal or more than 2 cm centimeters in size who desired a pregnancy and a control group of women (n = 300) with no previous recorded diagnosis of endometriosis who delivered in our clinic during the same time period.Intervention(s) Patient data collected from medical charts and by phone interviews.Main outcome measure(s) Evaluation of complications during pregnancy and delivery.Result(s) Of the 101 women with a posterior DIE nodule, 52 become pregnant among whom 25 used assisted reproductive technology. Of these 52 pregnancies, 11 ended in an early abortion, and 41 delivered a baby; 13 (31.7%) had a premature delivery, 7 (17.8%) a placenta praevia, and 28 (68.2%) had a cesarean delivery. When compared with the control group, the women with endometriosis had a higher risk of pregnancy complicated by preterm birth, placenta previa, placental abruption, and hypertension. Cesarean delivery and complications during surgery (hysterectomy, hemoperitoneum, and bladder injuries) were statistically significantly more frequent in women with endometriosis than in controls.Conclusion(s) Women with an incomplete removal of posterior DIE have a high complications rate during pregnancy and delivery.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
CD in women with DIE is more difficult and associated with more complications than CD in women without EM.
“CD in women with DIE is more difficult and associated with more complications than CD in women without EM.”
From Women with Endometriosis—Who Is at Risk for Complications Associated with Pregnancy and Childbirth? A Retrospective Case–Control Study (2024) · cites this paper as [18]
There is evidence that neonates born to mothers with AM are significantly lighter, more likely to be less than 2500 g and 1500 g, and to be below the 10th weight percentile compared to neonates of mothers without EM.
“There is evidence in the literature that neonates born to mothers with AM are significantly lighter, more likely to be less than 2500 g and 1500 g and to be below the 10th weight percentile compared to neonates of mothers without EM [18,19,27,34].”
From Women with Endometriosis—Who Is at Risk for Complications Associated with Pregnancy and Childbirth? A Retrospective Case–Control Study (2024) · cites this paper as [18]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 37 · Cited by 100
- Authors
- Exacoustos, C., Lauriola, I., Lazzeri, L., De Felice, G., & Zupi, E.
- Affiliations
- University of Parma (IT)
- University of Siena (IT)
- University of Rome Tor Vergata (IT)
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2016-10
- Volume
- 106
- Issue
- 5
- Pages
- 1129-1135.e1
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2501829607
- Cited by
- 100
- References
- 37
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 10 · 2023: 11 · 2022: 15 · 2021: 17 · 2020: 14 · 2019: 7 · 2018: 7 · 2017: 9 · 2016: 1
- FWCI
- 10.64
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Cineca Institutional Research Information System (Tor Vergata University) (submittedVersion)
- Use Siena air (University of Siena) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Health Sciences › Medicine › Obstetrics and Gynecology › Endometrial and Cervical Cancer Treatments
- Keywords
- deep infiltrating endometriosis, rectovaginal endometriosis, pregnancy complications, delivery complications, preterm birth, placenta previa, placental abruption, cesarean section, hysterectomy, hemoperitoneum, bladder injury, transvaginal ultrasound, assisted reproduction
- MeSH terms
- Adult, Cesarean Section, Endometriosis, Female, Humans, Infertility, Female, Italy, Pregnancy, Pregnancy Complications, Prospective Studies, Rectal Diseases, Risk Factors, Vaginal Diseases, Case-Control Studies, Ultrasonography, Prenatal, Treatment Outcome, Reproductive Techniques, Assisted, Parturition, Delivery, Obstetric, Live Birth, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
