Mannitol is essential for the development of stress-resistant ascospores in Neosartorya fischeri (Aspergillus fischeri)

Wyatt, T.T.; van Leeuwen, M.R.; Wösten, H.A.B.; Dijksterhuis, J.

doi:10.1016/j.fgb.2013.12.010

Mannitol is essential for the development of stress-resistant ascospores in Neosartorya fischeri (Aspergillus fischeri)

The polyol mannitol is one of the main compatible solutes in Neosartorya fischeri and accumulates in conidia and ascospores. Here, it is shown that biosynthesis of mannitol in N. fischeri mainly depends on mannitol 1-phosphate dehydrogenase (MpdA). Reporter studies and qPCR analysis demonstrated …