The DOI matches its Crossref record; 295 of the 295 references it cites were found in a registry or an index.
Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex
Open accessAbstract
Phylogenetic analysis of 11 genetic loci and results from many genotyping studies revealed significant genetic diversity with the pathogenic Cryptococcus gattii/Cryptococcus neoformans species complex. Genealogical concordance, coalescence-based, and species tree approaches supported the presence of distinct and concordant lineages within the complex. Consequently, we propose to recognize the current C. neoformans var. grubii and C. neoformans var. neoformans as separate species, and five species within C. gattii. The type strain of C. neoformans CBS132 represents a serotype AD hybrid and is replaced. The newly delimited species differ in aspects of pathogenicity, prevalence for patient groups, as well as biochemical and physiological aspects, such as susceptibility to antifungals. MALDI-TOF mass spectrometry readily distinguishes the newly recognized species.
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Metadata
- Authors
- Hagen, F., Khayhan, K., Theelen, B., Kolecka, A., Polacheck, I., Sionov, E., Falk, R., Parnmen, S., Lumbsch, H. T., & Boekhout, T.
- Venue
- Fungal Genetics and Biology
- Publisher
- Elsevier BV
- Published
- 2015-05
- Volume
- 78
- Pages
- 16-48
- ISSN
- 1087-1845 (ISSN-L)
- OpenAlex
- W1996229802
- Cited by
- 687
- References
- 295
- FWCI
- 52.75
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Hagen, F., Khayhan, K., Theelen, B., Kolecka, A., Polacheck, I., Sionov, E., Falk, R., Parnmen, S., Lumbsch, H. T., & Boekhout, T. (2015). Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex. Fungal Genetics and Biology. https://doi.org/10.1016/j.fgb.2015.02.009
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