Cited by 6Proteins in Food SystemsProtein Hydrolysis and Bioactive PeptidesFood Nutrient Composition and Product Development

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Impact of iron binding on the functional and digestive properties of potato protein fractions

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Li, Sisheng, Luo, Minna, Zhang, Yuzhen, Wong, Siu, Hu, Xiaoyan, Yan, Weixin, McClements, David Julian·2025·Food Hydrocolloids

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Crossref · 10.1016/j.foodhyd.2025.111129

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  • The increased hydrolysis of potato protein gels by iron binding is explained by iron acting as a cofactor for proteases during digestion.

    “which was explained that iron acted as a cofactor for the proteases during digestion”

    From Designing Protein Gels for Nutrient Delivery: From Formulation to Digestion (2026) · cites this paper as S. Li, Luo, et al. 2025

  • Iron binding increased the hydrolysis of potato protein gels with higher viscosity and gel strength.

    “Iron binding increased the hydrolysis of potato protein gels with higher viscosity and gel strength”

    From Designing Protein Gels for Nutrient Delivery: From Formulation to Digestion (2026) · cites this paper as S. Li, Luo, et al. 2025

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Research works printed but not linked: 63

  1. Ariëns, 2021, Comparing nutritional and digestibility aspects of sustainable proteins using the INFOGEST digestion protocol, Journal of Functional Foods, 87, 10.1016/j.jff.2021.104748 · DOI
  2. Azari, 1958, Resistance of metal complexes of conalbumin and transferrin to proteolysis and to thermal denaturation, Journal of Biological Chemistry, 232, 293, 10.1016/S0021-9258(18)70395-5 · DOI
  3. Bártová, 2019, Antifungal and antimicrobial proteins and peptides of potato (Solanum tuberosum L.) tubers and their applications, Applied Microbiology and Biotechnology, 103, 5533, 10.1007/s00253-019-09887-9 · DOI
  4. Beal, 2023, Estimated micronutrient shortfalls of the EAT–Lancet planetary health diet, The Lancet Planetary Health, 7, e233, 10.1016/S2542-5196(23)00006-2 · DOI
  5. Blanco-Rojo, 2019, Iron bioavailability from food fortification to precision nutrition. A review, Innovative Food Science & Emerging Technologies, 51, 126, 10.1016/j.ifset.2018.04.015 · DOI
  6. Bohn, 2008, Phytate: Impact on environment and human nutrition. A challenge for molecular breeding, Journal of Zhejiang University - Science B, 9, 165, 10.1631/jzus.B0710640 · DOI
  7. Bouhallab, 2002, Influence of various phosphopeptides of caseins on iron absorption, Journal of Agricultural and Food Chemistry, 50, 7127, 10.1021/jf025554v · DOI
  8. Brodkorb, 2019, INFOGEST static in vitro simulation of gastrointestinal food digestion, Nature Protocols, 14, 991, 10.1038/s41596-018-0119-1 · DOI · Paper page
  9. Budseekoad, 2018, Structural and functional characterization of calcium and iron-binding peptides from mung bean protein hydrolysate, Journal of Functional Foods, 49, 333, 10.1016/j.jff.2018.07.041 · DOI
  10. Camire, 2009, Potatoes and human health, Critical Reviews in Food Science and Nutrition, 49, 823, 10.1080/10408390903041996 · DOI
  11. Cappellini, 2020, Iron deficiency anaemia revisited, Journal of Internal Medicine, 287, 153, 10.1111/joim.13004 · DOI
  12. Chungchunlam, 2024, Diet affordability: A key dimension in the assessment of sustainable food systems and healthy diets, Frontiers in Nutrition, 11, 10.3389/fnut.2024.1399019 · DOI
  13. de la Hoz, 2014, Iron-binding properties of sugar cane yeast peptides, Food Chemistry, 142, 166, 10.1016/j.foodchem.2013.06.133 · DOI
  14. Dehnad, 2023, Recent advances in iron encapsulation and its application in food fortification, Critical Reviews in Food Science and Nutrition, 1
  15. Diermayr, 1990, Controlled enzymatic hydrolysis of proteins at low pH values 1. Experiments with bovine serum albumin: 1. Mitteilung: Versuche mit Rinderserumalbumin, Zeitschrift für Lebensmittel-Untersuchung und Forschung, 190, 516, 10.1007/BF01214073 · DOI
  16. Donovan, 1975, Iron binding to conalbumin. Calorimetric evidence for two distinct species with one bound iron atom, Journal of Biological Chemistry, 250, 6026, 10.1016/S0021-9258(19)41153-8 · DOI
  17. Eckert, 2016, Biophysical and in vitro absorption studies of iron chelating peptide from barley proteins, Journal of Functional Foods, 25, 291, 10.1016/j.jff.2016.06.011 · DOI
  18. Ferreira, 2018, Lactoferrin denaturation induced by anionic surfactants: The role of the ferric ion in the protein stabilization, International Journal of Biological Macromolecules, 117, 1039, 10.1016/j.ijbiomac.2018.05.058 · DOI
  19. Galaris, 2019, Iron homeostasis and oxidative stress: An intimate relationship, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1866, 10.1016/j.bbamcr.2019.118535 · DOI
  20. Ghio, 2013, Deficiency of α-1-antitrypsin influences systemic iron homeostasis, International Journal of Chronic Obstructive Pulmonary Disease, 8, 45, 10.2147/COPD.S37897 · DOI
  21. He, 2013, Digestion kinetics of potato protein isolates in vitro and in vivo, International Journal of Food Sciences & Nutrition, 64, 787, 10.3109/09637486.2013.793300 · DOI
  22. Hirvonen, 2020, Affordability of the EAT–lancet reference diet: A global analysis, Lancet Global Health, 8, e59, 10.1016/S2214-109X(19)30447-4 · DOI
  23. Hsu, 2020, Iron: An essential element of cancer metabolism, Cells, 9, 2591, 10.3390/cells9122591 · DOI
  24. Hu, 2023, Iron delivery systems for controlled release of iron and enhancement of iron absorption and bioavailability, Critical Reviews in Food Science and Nutrition, 63, 10197, 10.1080/10408398.2022.2076652 · DOI
  25. Hu, 2022, Exploration of iron-binding mode, digestion Kinetics, and iron absorption behavior of Antarctic Krill–derived heptapeptide–iron complex, Food Research International, 154, 10.1016/j.foodres.2022.110996 · DOI
  26. Hu, 2024, Impact of lipid droplet characteristics on the rheology of plant protein emulsion gels: Droplet size, concentration, and interfacial properties, Food Research International, 191, 10.1016/j.foodres.2024.114734 · DOI
  27. Hurrell, 2010, Iron bioavailability and dietary reference values1234, The American Journal of Clinical Nutrition, 91, 1461S, 10.3945/ajcn.2010.28674F · DOI · Paper page
  28. Hussain, 2021, Potato protein: An emerging source of high quality and allergy free protein, and its possible future based products, Food Research International, 148, 10.1016/j.foodres.2021.110583 · DOI
  29. Kazemi-Taskooh, 2021, Food-based iron delivery systems: A review, Trends in Food Science & Technology, 116, 75, 10.1016/j.tifs.2021.07.005 · DOI
  30. Kumar, 2023, New insights in improving sustainability in meat production: Opportunities and challenges, Critical Reviews in Food Science and Nutrition, 63, 11830, 10.1080/10408398.2022.2096562 · DOI
  31. Li, 2024, Fabrication, characterization, and application of pea protein isolate-polyphenol-iron complexes with antioxidant and antibacterial activity, Food Hydrocolloids, 150, 10.1016/j.foodhyd.2024.109729 · DOI
  32. Li, 2022, Edible mayonnaise-like Pickering emulsion stabilized by pea protein isolate microgels: Effect of food ingredients in commercial mayonnaise recipe, Food Chemistry, 376, 10.1016/j.foodchem.2021.131866 · DOI
  33. Li, 2024, Development of novel protein-rich foods: Studies of composite hydrogels formed from potato proteins and gellan gums with different degrees of acylation, Food Hydrocolloids, 157, 10.1016/j.foodhyd.2024.110387 · DOI
  34. Li, 2024, Exploring the potential of plant-based emulsion gels enriched with β-glucan and potato protein as egg yolk alternatives, Food Hydrocolloids, 148, 10.1016/j.foodhyd.2023.109511 · DOI
  35. Li, 2023, Controlling textural attributes of plant-based emulsions using heteroaggregation of cationic and anionic potato protein-coated oil droplets, Food Hydrocolloids, 145, 10.1016/j.foodhyd.2023.109126 · DOI
  36. Lima, 2022, A narrative review of alternative protein sources: Highlights on meat, fish, egg and dairy analogues, Foods, 11, 2053, 10.3390/foods11142053 · DOI
  37. Liu, 2019, Rheological and mechanical behavior of milk protein composite gel for extrusion-based 3D food printing, Lwt, 102, 338, 10.1016/j.lwt.2018.12.053 · DOI
  38. Man, 2022, Iron supplementation and iron-fortified foods: A review, Critical Reviews in Food Science and Nutrition, 62, 4504, 10.1080/10408398.2021.1876623 · DOI
  39. Nielsen, 2001, Improved method for determining food protein degree of hydrolysis, Journal of Food Science, 66, 642, 10.1111/j.1365-2621.2001.tb04614.x · DOI
  40. Ozel, 2020, Digestion of animal- and plant-based proteins encapsulated in κ-carrageenan/protein beads under simulated gastrointestinal conditions, Food Research International, 137, 10.1016/j.foodres.2020.109662 · DOI
  41. Papuc, 2017, Mechanisms of oxidative processes in meat and toxicity induced by postprandial degradation products: A review, Comprehensive Reviews in Food Science and Food Safety, 16, 96, 10.1111/1541-4337.12241 · DOI
  42. Perez-Guzman, 2010, Vol. 3
  43. Pinckaers, 2022, Potato protein ingestion increases muscle protein synthesis rates at rest and during recovery from exercise in humans, Medicine & Science in Sports & Exercise, 54, 1572, 10.1249/MSS.0000000000002937 · DOI
  44. Pots, 1999, Isolation and characterization of patatin isoforms, Journal of Agricultural and Food Chemistry, 47, 4587, 10.1021/jf981180n · DOI
  45. Roux, 2020, In vitro static digestion reveals how plant proteins modulate model infant formula digestibility, Food Research International, 130, 10.1016/j.foodres.2019.108917 · DOI
  46. Schoenbeck, 2013, Purification of high value proteins from particle containing potato fruit juice via direct capture membrane adsorption chromatography, Journal of Biotechnology, 168, 693, 10.1016/j.jbiotec.2013.09.018 · DOI
  47. Sharp, 2007, Molecular mechanisms involved in intestinal iron absorption, World Journal of Gastroenterology, 13, 4716, 10.3748/wjg.v13.i35.4716 · DOI · Paper page
  48. Shubham, 2020, Iron deficiency anemia: A comprehensive review on iron absorption, bioavailability and emerging food fortification approaches, Trends in Food Science & Technology, 99, 58, 10.1016/j.tifs.2020.02.021 · DOI
  49. Stading, 1990, Viscoelastic behaviour of β-lactoglobulin gel structures, Food Hydrocolloids, 4, 121, 10.1016/S0268-005X(09)80013-1 · DOI
  50. Tan, 2023, Influence of different nano/micro-carriers on the bioavailability of iron: Focus on in vitro–in vivo studies, Advances in Colloid and Interface Science, 318, 10.1016/j.cis.2023.102949 · DOI
  51. Tan, 2023, Utilization of potato protein fractions to form oil-in-water nanoemulsions: Impact of pH, salt, and heat on their stability, Food Hydrocolloids, 137, 10.1016/j.foodhyd.2022.108356 · DOI
  52. Tarhan, 2016, Rheological and structural characterization of whey protein gelation induced by enzymatic hydrolysis, Food Hydrocolloids, 61, 211, 10.1016/j.foodhyd.2016.04.042 · DOI
  53. Tso, 2020, A critical appraisal of the evidence supporting consumer motivations for alternative proteins, Foods, 10, 24, 10.3390/foods10010024 · DOI
  54. Waglay, 2014, Potato protein isolates: Recovery and characterization of their properties, Food Chemistry, 142, 373, 10.1016/j.foodchem.2013.07.060 · DOI
  55. 2023, Vol. 2023
  56. Wu, 2018, Reducing the allergenic capacity of β-lactoglobulin by covalent conjugation with dietary polyphenols, Food Chemistry, 256, 427, 10.1016/j.foodchem.2018.02.158 · DOI
  57. Yasumaru, 2014, Species specific in vitro protein digestion (pH-stat) for fish: Method development and application for juvenile rainbow trout (Oncorhynchus mykiss), cobia (Rachycentron canadum), and nile tilapia (Oreochromis niloticus), Aquaculture, 426–427, 74, 10.1016/j.aquaculture.2014.01.012 · DOI
  58. Zainal, 2020, Melt rheological behavior and morphology of poly(ethylene oxide)/natural rubber-graft-poly(methyl methacrylate) blends, Polymers, 12, 10.3390/polym12030724 · DOI
  59. Zhang, 2014, Iron binding capacity of dephytinised soy protein isolate hydrolysate as influenced by the degree of hydrolysis and enzyme type, Journal of Food Science & Technology, 51, 994, 10.1007/s13197-011-0586-7 · DOI
  60. Zhang, 2022, Production of plant-based seafood: Scallop analogs formed by enzymatic gelation of pea protein-pectin mixtures, Foods, 11, 851, 10.3390/foods11060851 · DOI
  61. Zhang, 2023, Characterization of Fe(III)-binding peptides from pea protein hydrolysates targeting enhanced iron bioavailability, Food Chemistry, 405, 10.1016/j.foodchem.2022.134887 · DOI
  62. Zhou, 2021, Digestibility and gastrointestinal fate of meat versus plant-based meat analogs: An in vitro comparison, Food Chemistry, 364, 10.1016/j.foodchem.2021.130439 · DOI
  63. Zia, 2018, Recent trends on gellan gum blends with natural and synthetic polymers: A review, International Journal of Biological Macromolecules, 109, 1068, 10.1016/j.ijbiomac.2017.11.099 · DOI

Cited by

Sorted by citations

Metadata

Authors
Li, S., Luo, M., Zhang, Y., Wong, S., Hu, X., Yan, W., & McClements, D. J.
Affiliations
University of Massachusetts Amherst (US)
Corresponding author
McClements, David Julian
Venue
Food Hydrocolloids
Publisher
Elsevier BV
Published
2025-06
Volume
163
Pages
111129
ISSN
0268-005X (ISSN-L)
OpenAlex
W4406999392
Cited by
6
References
0
Citations by year
2026: 4 · 2025: 2
FWCI
2.83
Type
journal article
Language
en
Open access
Locations
Food Hydrocolloids (acceptedVersion)
Funders
  • U.S. Department of Agriculture
  • China Scholarship Council
  • Massachusetts Agricultural Experiment Station (MAS00559)
  • National Institute of Food and Agriculture
  • Good Food Institute
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Protein Hydrolysis and Bioactive Peptides
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food Nutrient Composition and Product Development
Keywords
iron binding, patatin, protease inhibitors, protein functional properties, proteolysis, in vitro digestion, iron bioaccessibility, viscosity, viscoelasticity, iron deficiency, iron-fortified foods, plant proteins

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