A retrospective analysis of data from forensic toxicology at the Academy of Forensic Science in 2017
Abstract
Knowing the specific pattern of forensic toxicology cases in a region is vital to help the local government establish an effective prevention and treatment system; currently, there have been no published reports investigating various types of forensic toxicology cases based on a large autopsy series and city size. The data in this study were obtained from records kept at the Academy of Forensic Science (AFS) between February 2017 and December 2017, and the cases were mainly from the Public Security Organs People's Police in Shanghai, China. There were 299 autopsies; the leading cause of death was traffic accidents (37.1%), and the manners of death were mainly accidental (54.8%). From a total of 9083 cases, 1992 involved traffic accidents, 6787 were drug abuse, 269 were poisonings, and 35 were drug-facilitated sexual assaults (DFSAs). We also investigated the pattern of unnatural deaths and the alcohol-positive (with a blood alcohol concentration (BAC) ≥0.20 mg/ml) rate among the various cases. The BAC ranged from 0.08 to 7.24 mg/ml in traffic cases, and the mean BAC of the total alcohol-positive drivers was 1.44 mg/ml. It was found that 80.8% of the drivers involved had a BAC ≥ 0.20 mg/ml (limit of civil offense), and 72.8% had a BAC ≥ 0.80 mg/ml (limit of criminal offense). Among the drug abuse cases, there were 4073 cases (60.0%) that were positive for at least one euphoriant; the most frequently abused drug group was amphetamine-type stimulants (ATS). Poisonings by natural toxins (such as scopolamine and tetrodotoxin) account for a significant portion of accidental deaths. Pesticide poisoning was also constituted a large portion, and organophosphorus were the cause of the majority of those cases. Suicide by pesticide showed the highest frequency in the present study. Among the 35 DFSA cases, dexmedetomidine was frequently detected in our study, which has rarely been reported previously in DFSA cases.
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In China, Pan et al. found that 13% of deaths were poisoning cases, of which 12.8% were suicides.
“In China, a retrospective study conducted on 299 autopsy cases by Pan et al. [23] showed that 13% (n = 39) of the deaths were poisoning cases, of which 12.8% (n = 5) were suicides.”
From Toxicological Findings of Self-Poisoning Suicidal Deaths: A Systematic Review by Countries (2022) · cites this paper as [23]
The autopsy rate in deaths by suicide and poisoning is still low.
“The autopsy rate in deaths by suicide and poisoning is still low [21,22,23,24,25,26,27,28].”
From Toxicological Findings of Self-Poisoning Suicidal Deaths: A Systematic Review by Countries (2022) · cites this paper as [23]
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Toxicological Findings of Self-Poisoning Suicidal Deaths: A Systematic Review by Countries
Albano, G. D., Malta, G., La Spina, C., Rifiorito, A., Provenzano, V., Triolo, V., Vaiano, F., Bertol, E., Zerbo, S., & Argo, A. (2022) · Toxics · doi:10.3390/toxics10110654 · Cited by 58 · see citing works
- Authors
- Pan, M., Wang, X., Zhao, Y., Liu, W., & Xiang, P.
- Affiliations
- Shenyang Pharmaceutical University (CN)
- Corresponding author
- Liu, Wei
- Xiang, Ping
- Venue
- Forensic Science International
- Publisher
- Elsevier BV
- Published
- 2019-05
- Volume
- 298
- Pages
- 39-47
- ISSN
- 0379-0738 (ISSN-L)
- OpenAlex
- W2919152961
- Cited by
- 31
- References
- 0
- Citations by year
- 2026: 4 · 2025: 2 · 2023: 10 · 2022: 10 · 2021: 2 · 2020: 1 · 2019: 2
- FWCI
- 2.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Forensic Science International (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Finance (GY2017G-1)
- Ministry of Science and Technology of the People's Republic of China (2016YFC0800704)
- Science and Technology Commission of Shanghai Municipality (17DZ2273200/16DZ2290900)
- National Natural Science Foundation of China (81772022, 81871531)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
- Health Sciences › Medicine › Emergency Medicine › Poisoning and overdose treatments
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- forensic toxicology, autopsy findings, traffic accidents, drug abuse, blood alcohol concentration, amphetamine-type stimulants, pesticide poisoning, organophosphate poisoning, suicide, drug-facilitated sexual assault, dexmedetomidine, scopolamine, tetrodotoxin, accidental death, Shanghai
- MeSH terms
- Accidents, Traffic, Blood Alcohol Content, Cause of Death, China, Death, Sudden, Homicide, Humans, Retrospective Studies, Suicide, Wounds and Injuries, Substance Abuse Detection, Substance-Related Disorders, Forensic Sciences
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