Cited by 31Forensic Toxicology and Drug AnalysisPoisoning and overdose treatmentsSubstance Abuse Treatment and Outcomes

A retrospective analysis of data from forensic toxicology at the Academy of Forensic Science in 2017

Pan, Meiru, Wang, Xin, Zhao, Yunli, Liu, Wei, Xiang, Ping·2019·Forensic Science International

Abstract

Knowing the specific pattern of forensic toxicology cases in a region is vital to help the local government establish an effective prevention and treatment system; currently, there have been no published reports investigating various types of forensic toxicology cases based on a large autopsy series and city size. The data in this study were obtained from records kept at the Academy of Forensic Science (AFS) between February 2017 and December 2017, and the cases were mainly from the Public Security Organs People's Police in Shanghai, China. There were 299 autopsies; the leading cause of death was traffic accidents (37.1%), and the manners of death were mainly accidental (54.8%). From a total of 9083 cases, 1992 involved traffic accidents, 6787 were drug abuse, 269 were poisonings, and 35 were drug-facilitated sexual assaults (DFSAs). We also investigated the pattern of unnatural deaths and the alcohol-positive (with a blood alcohol concentration (BAC) ≥0.20 mg/ml) rate among the various cases. The BAC ranged from 0.08 to 7.24 mg/ml in traffic cases, and the mean BAC of the total alcohol-positive drivers was 1.44 mg/ml. It was found that 80.8% of the drivers involved had a BAC ≥ 0.20 mg/ml (limit of civil offense), and 72.8% had a BAC ≥ 0.80 mg/ml (limit of criminal offense). Among the drug abuse cases, there were 4073 cases (60.0%) that were positive for at least one euphoriant; the most frequently abused drug group was amphetamine-type stimulants (ATS). Poisonings by natural toxins (such as scopolamine and tetrodotoxin) account for a significant portion of accidental deaths. Pesticide poisoning was also constituted a large portion, and organophosphorus were the cause of the majority of those cases. Suicide by pesticide showed the highest frequency in the present study. Among the 35 DFSA cases, dexmedetomidine was frequently detected in our study, which has rarely been reported previously in DFSA cases.

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Crossref · 10.1016/j.forsciint.2019.02.039

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Authors
Pan, M., Wang, X., Zhao, Y., Liu, W., & Xiang, P.
Affiliations
Shenyang Pharmaceutical University (CN)
Corresponding author
  • Liu, Wei
  • Xiang, Ping
Venue
Forensic Science International
Publisher
Elsevier BV
Published
2019-05
Volume
298
Pages
39-47
ISSN
0379-0738 (ISSN-L)
OpenAlex
W2919152961
Cited by
31
References
0
Citations by year
2026: 4 · 2025: 2 · 2023: 10 · 2022: 10 · 2021: 2 · 2020: 1 · 2019: 2
FWCI
2.79
Type
journal article
Language
en
Open access
closed
Locations
  • Forensic Science International (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Ministry of Finance (GY2017G-1)
  • Ministry of Science and Technology of the People's Republic of China (2016YFC0800704)
  • Science and Technology Commission of Shanghai Municipality (17DZ2273200/16DZ2290900)
  • National Natural Science Foundation of China (81772022, 81871531)
Topics
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
  • Health Sciences › Medicine › Emergency Medicine › Poisoning and overdose treatments
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
forensic toxicology, autopsy findings, traffic accidents, drug abuse, blood alcohol concentration, amphetamine-type stimulants, pesticide poisoning, organophosphate poisoning, suicide, drug-facilitated sexual assault, dexmedetomidine, scopolamine, tetrodotoxin, accidental death, Shanghai
MeSH terms
Accidents, Traffic, Blood Alcohol Content, Cause of Death, China, Death, Sudden, Homicide, Humans, Retrospective Studies, Suicide, Wounds and Injuries, Substance Abuse Detection, Substance-Related Disorders, Forensic Sciences

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