The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Identification of ICE2, a gene involved in cold acclimation which determines freezing tolerance in Arabidopsis thaliana
Abstract
Several transcription factors are presently known to regulate the response to cold stress. Here we describe a new positive regulator, ICE2, which is a transcription factor of the bHLH family that participates in the response to deep freezing through the cold acclimation-dependent pathway in Arabidopsis thaliana plants. An overexpression of ICE2 (as we named the At1g12860 locus) in transgenic Arabidopsis plants results in increased tolerance to deep freezing stress after cold acclimation. The seeds of transgenic lines that overexpressed ICE2 were characterized by decreased levels of carbohydrate and increased levels of lipids. The analysis of expression of CBF1 gene (also known as DREB1B), which have been shown to be required for the complete development of cold acclimation response in Arabidopsis indicated a difference between expression of the CBF1 gene in transgenic plants and the wild-type control plants, Col-0. These results suggested that the CBF1 transcription factor, known as one of the regulators of the cold stress response, has a dominant role in providing freezing tolerance in transgenic plants characterized by overexpression of ICE2.
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“The bHLH transcription factors, mainly ICEs (inducers of CBF expression) induced by the cold are crucial for cold stress tolerance (Fursova et al. 2009), but their role in terpenoid biosynthesis has not been validated.”
From Enhancing artemisinin content in and delivery from Artemisia annua: a review of alternative, classical, and transgenic approaches (2021) · cites this paper as Fursova et al. 2009
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ICE1: a regulator of cold-induced transcriptome and freezing tolerance in ArabidopsisPreprint
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THE UBIQUITIN 26S PROTEASOME PROTEOLYTIC PATHWAY
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The Arabidopsis Basic/Helix-Loop-Helix Transcription Factor Family[W]
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Ding, Y., Shi, Y., & Yang, S. (2019) · New Phytologist · doi:10.1111/nph.15696 · Cited by 983
Signal transduction during cold, salt, and drought stresses in plants
Huang, G., Ma, S., Bai, L.-P., Zhang, L., Ma, H., Jia, P., Liu, J., Zhong, M., & Guo, Z. (2011) · Molecular Biology Reports · doi:10.1007/s11033-011-0823-1 · Cited by 865
Molecular Regulation of CBF Signaling in Cold Acclimation
Shi, Y., Ding, Y., & Yang, S. (2018) · Trends in Plant Science · doi:10.1016/j.tplants.2018.04.002 · Cited by 869
Hu, Y., Jiang, L., Wang, F., & Yu, D. (2013) · The Plant Cell · doi:10.1105/tpc.113.112631 · Cited by 831
Molecular Regulation of Plant Responses to Environmental Temperatures
Ding, Y., Shi, Y., & Yang, S. (2020) · Molecular Plant · doi:10.1016/j.molp.2020.02.004 · Cited by 804
Metadata
- Authors
- Fursova, O. V., Pogorelko, G. V., & Tarasov, V. A.
- Affiliations
- Russian Academy of Sciences (RU)
- Corresponding author
- Pogorelko, Gennady V.
- Venue
- Gene
- Publisher
- Elsevier BV
- Published
- 2009-01
- Volume
- 429
- Issue
- 1-2
- Pages
- 98-103
- ISSN
- 0378-1119 (ISSN-L)
- OpenAlex
- W2028463864
- Cited by
- 276
- References
- 26
- Citations by year
- 2026: 9 · 2025: 15 · 2024: 14 · 2023: 22 · 2022: 20 · 2021: 27 · 2020: 22 · 2019: 13 · 2018: 20 · 2017: 15 · 2016: 11 · 2015: 18 · 2014: 18 · 2013: 16 · 2012: 11
- FWCI
- 10.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Gene (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Institut National de la Recherche Agronomique
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Seed Germination and Physiology
- Keywords
- bHLH transcription factors, cold acclimation, freezing tolerance, cold stress response, CBF1, transgenic overexpression, seed oil content, seed carbohydrate content, Arabidopsis thaliana
- MeSH terms
- Acclimatization, Amino Acid Sequence, Carbohydrates, Freezing, Lipids, Molecular Sequence Data, Mutation, RNA, Messenger, Seeds, Trans-Activators, Survival Analysis, Sequence Alignment, Genes, Plant, Arabidopsis, Gene Expression Regulation, Plant, Arabidopsis Proteins, Plants, Genetically Modified, Seedlings, Phase Transition, Basic Helix-Loop-Helix Proteins
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