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MYH9: Structure, functions and role of non-muscle myosin IIA in human disease
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“Recent studies have linked both RHOH and NMHC IIA to cancers [53,62,63].”
From Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils (2022) · cites this paper as [63]
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- Adelstein, 1975, Phosphorylation of platelet myosin increases actin-activated myosin ATPase activity, Nature, 256, 597, 10.1038/256597a0 · DOI
- Baird, 2017, Local pulsatile contractions are an intrinsic property of the myosin 2A motor in the cortical cytoskeleton of adherent cells, Mol. Biol. Cell, 28, 240, 10.1091/mbc.e16-05-0335 · DOI
- Badirou, 2015, Distinct localizations and roles of non-muscle myosin II during proplatelet formation and platelet release, J. Thromb. Haemost., 13, 851, 10.1111/jth.12887 · DOI
- Beach, 2015, Myosin II isoform co-assembly and differential regulation in mammalian systems, Exp. Cell Res., 334, 2, 10.1016/j.yexcr.2015.01.012 · DOI
- Beach, 2011, Myosin II isoform switching mediates invasiveness after TGF-beta-induced epithelial-mesenchymal transition, Proc. Natl. Acad. Sci. U. S. A., 108, 17991, 10.1073/pnas.1106499108 · DOI
- Beach, 2011, Analysis of the role of Ser1/Ser2/Thr9 phosphorylation on myosin II assembly and function in live cells, BMC Cell Biol., 12, 52, 10.1186/1471-2121-12-52 · DOI
- Beach, 2014, Nonmuscle myosin II isoforms coassemble in living cells, Curr. Biol., 24, 1160, 10.1016/j.cub.2014.03.071 · DOI
- Beckerman, 2017, Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice, Nat. Med., 23, 429, 10.1038/nm.4287 · DOI · Paper page
- Balduini, 2008, Adhesive receptors, extracellular proteins and myosin IIA orchestrate proplatelet formation by human megakaryocytes, J. Thromb. Haemost., 6, 1900, 10.1111/j.1538-7836.2008.03132.x · DOI
- Balduini, 2013, Diagnosis and management of inherited thrombocytopenias, Semin. Thromb. Hemost., 39, 161, 10.1055/s-0032-1333540 · DOI
- Billington, 2015, Myosin 18A coassembles with nonmuscle myosin 2 to form mixed bipolar filaments, Curr. Biol., 25, 942, 10.1016/j.cub.2015.02.012 · DOI
- Bresnick, 2015, S100 proteins in cancer, Nat. Rev. Cancer, 15, 96, 10.1038/nrc3893 · DOI
- Burgess, 2007, Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state, J. Mol. Biol., 372, 1165, 10.1016/j.jmb.2007.07.014 · DOI
- Cechova, 2018, MYH9 E1841K mutation augments proteinuria and podocyte injury and migration, J. Am. Soc. Nephrol., 29, 155, 10.1681/ASN.2015060707 · DOI
- Chen, 2007, The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway, Blood, 110, 171, 10.1182/blood-2007-02-071589 · DOI
- Cheng, 2011, Polymorphisms in the nonmuscle myosin heavy chain 9 gene (MYH9) are associated with the progression of IgA nephropathy in Chinese, Nephrol. Dial. Transplant., 26, 2544, 10.1093/ndt/gfq768 · DOI
- Conti, 2004, Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice, J. Biol. Chem., 279, 41263, 10.1074/jbc.C400352200 · DOI
- Conti, 2015, Conditional deletion of nonmuscle myosin II-A in mouse tongue epithelium results in squamous cell carcinoma, Sci. Rep., 5, 14068, 10.1038/srep14068 · DOI
- Cooke, 2012, Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans, Nephrol. Dial. Transplant., 27, 1505, 10.1093/ndt/gfr522 · DOI
- Craig, 1983, Light-chain phosphorylation controls the conformation of vertebrate non-muscle and smooth muscle myosin molecules, Nature, 302, 436, 10.1038/302436a0 · DOI
- Crish, 2013, Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality, Dev. Biol., 382, 136, 10.1016/j.ydbio.2013.07.017 · DOI
- Clark, 2008, The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC, FEBS Lett., 582, 2993, 10.1016/j.febslet.2008.07.043 · DOI
- Clark, 2008, TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation, J. Mol. Biol., 378, 790, 10.1016/j.jmb.2008.02.057 · DOI
- Cross, 2006, Branching morphogenesis during development of placental villi, Differentiation, 74, 393, 10.1111/j.1432-0436.2006.00103.x · DOI
- Dahan, 2014, The tumor suppressor Lgl1 forms discrete complexes with NMII-A and Par6alpha-aPKCzeta that are affected by Lgl1 phosphorylation, J. Cell Sci., 127, 295
- D'Apolito, 2002, Cloning of the murine nonmuscle heavy chain myosin IIA gene, ortholog of human MYH9 responsible for May-Hegglin, Sebastian, Fechtner, and Epstein syndromes, Gene, 286, 215, 10.1016/S0378-1119(02)00455-9 · DOI
- De Rocco, 2009, Identification of the first duplication in MYH9-related disease: a hot spot for unequal crossing-over within exon 24 of the MYH9 gene, Eur. J. Med. Genet., 52, 191, 10.1016/j.ejmg.2009.01.006 · DOI
- Derycke, 2011, The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells, Int. J. Dev. Biol., 55, 835, 10.1387/ijdb.113336ld · DOI
- Dong, 2005, Genotype-phenotype correlation in MYH9-relatedthrombocytopenia, Br. J. Haematol., 130, 620, 10.1111/j.1365-2141.2005.05658.x · DOI
- Dulyaninova, 2013, The heavy chain has its day: regulation of myosin-II assembly, BioArchitecture, 3, 77, 10.4161/bioa.26133 · DOI
- Dulyaninova, 2007, Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells, Mol. Biol. Cell, 18, 3144, 10.1091/mbc.e06-11-1056 · DOI
- Ebrahim, 2013, NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry, Curr. Biol., 23, 731, 10.1016/j.cub.2013.03.039 · DOI
- Eddinger, 2007, Myosin II isoforms in smooth muscle: heterogeneity and function, Am. J. Phys. Cell Physiol., 293, C493, 10.1152/ajpcell.00131.2007 · DOI
- Favier, 2013, First successful use of eltrombopag before surgery in a child with MYH9-related thrombocytopenia, Pediatrics, 132, e793, 10.1542/peds.2012-3807 · DOI
- Favier, 2018, Eltrombopag to treat thrombocytopenia during last month of pregnancy in a woman with MYH9-related disease: a case report, A A Pract., 10, 10, 10.1213/XAA.0000000000000621 · DOI
- Foth, 2006, New insights into myosin evolution and classification, Proc. Natl. Acad. Sci. U. S. A., 103, 3681, 10.1073/pnas.0506307103 · DOI
- Genovese, 2010, Association of trypanolytic ApoL1 variants with kidney disease in African Americans, Science, 329, 841, 10.1126/science.1193032 · DOI · Paper page
- Golomb, 2004, Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family, J. Biol. Chem., 279, 2800, 10.1074/jbc.M309981200 · DOI
- Greinacher, 2017, Diagnosis of inherited platelet disorders on a blood smear: a tool to facilitate worldwide diagnosis of platelet disorders, J. Thromb. Haemost., 15, 1511, 10.1111/jth.13729 · DOI
- Gresele, 2013, Apparent genotype-phenotype mismatch in a patient with MYH9-related disease: when the exception proves the rule, Thromb. Haemost., 110, 618, 10.1160/TH13-02-0175 · DOI
- Grum-Schwensen, 2005, Suppression of tumor development and metastasis formation in mice lacking the S100A4(mts1) gene, Cancer Res., 65, 3772, 10.1158/0008-5472.CAN-04-4510 · DOI
- Han, 2011, Renal manifestations of patients with MYH9-related disorders, Pediatr. Nephrol., 26, 549, 10.1007/s00467-010-1735-3 · DOI
- Heissler, 2013, Nonmuscle myosin-2: mix and match, Cell. Mol. Life Sci., 70, 1, 10.1007/s00018-012-1002-9 · DOI
- Heissler, 2016, Kinetic adaptations of myosins for their diverse cellular functions, Traffic, 17, 839, 10.1111/tra.12388 · DOI
- Heynen, 1988, Congenital macrothrombocytopenia, leukocyte inclusions, deafness and proteinuria: functional and electron microscopic observations on platelets and megakaryocytes, Br. J. Haematol., 70, 441, 10.1111/j.1365-2141.1988.00441.x · DOI
- Hosono, 2012, MYBPH inhibits NM IIA assembly via direct interaction with NMHC IIA and reduces cell motility, Biochem. Biophys. Res. Commun., 428, 173, 10.1016/j.bbrc.2012.10.036 · DOI
- Hu, 2002, Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function, J. Biol. Chem., 277, 46512, 10.1074/jbc.M208506200 · DOI
- Hundt, 2016, Load-dependent modulation of non-muscle myosin-2A function by tropomyosin 4.2, Sci. Rep., 6, 10.1038/srep20554 · DOI
- Ikebe, 1990, Phosphorylation of bovine platelet myosin by protein kinase C, Biochemistry, 29, 2713, 10.1021/bi00463a014 · DOI
- Italiano, 1999, Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes, J. Cell Biol., 147, 1299, 10.1083/jcb.147.6.1299 · DOI
- Jung, 2008, Head-head and head-tail interaction: a general mechanism for switching off myosin II activity in cells, Mol. Biol. Cell, 19, 3234, 10.1091/mbc.e08-02-0206 · DOI
- Kahr, 2009, Megakaryocyte and platelet abnormalities in a patient with a W33C mutation in the conserved SH3-like domain of myosin heavy chain IIA, Thromb. Haemost., 102, 1241, 10.1160/TH09-02-0119 · DOI
- Kao, 2008, MYH9 is associated with nondiabetic end-stage renal disease in African Americans, Nat. Genet., 40, 1185, 10.1038/ng.232 · DOI
- Kas, 2017, Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma, Nat. Genet., 49, 1219, 10.1038/ng.3905 · DOI
- Kassianidou, 2017, Activation of ROCK and MLCK tunes regional stress fiber formation and mechanics via preferential myosin light chain phosphorylation, Mol. Biol. Cell, 28, 3832, 10.1091/mbc.e17-06-0401 · DOI
- Katono, 2015, Prognostic significance of MYH9 expression in resected non-small cell lung cancer, PLoS One, 10, 10.1371/journal.pone.0121460 · DOI
- Kaushansky, 2015, Thrombopoiesis, Semin. Hematol., 52, 4, 10.1053/j.seminhematol.2014.10.003 · DOI
- Kawamoto, 1991, Chicken nonmuscle myosin heavy chains: differential expression of two mRNAs and evidence for two different polypeptides, J. Cell Biol., 112, 915, 10.1083/jcb.112.5.915 · DOI
- Kawamoto, 1989, In situ phosphorylation of human platelet myosin heavy and light chains by protein kinase C, J. Biol. Chem., 264, 2258, 10.1016/S0021-9258(18)94170-0 · DOI
- Kim, 2005, Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C, J. Biol. Chem., 280, 22769, 10.1074/jbc.M503488200 · DOI
- Kim, 2016, Genetic association of MYH genes with hereditary hearing loss in Korea, Gene, 591, 177, 10.1016/j.gene.2016.07.011 · DOI
- Kiss, 2012, Crystal structure of the S100A4-nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism, Proc. Natl. Acad. Sci. U. S. A., 109, 6048, 10.1073/pnas.1114732109 · DOI
- Kitamura, 2013, Normal neutrophil myosin IIA localization in an immunofluorescence analysis can rule out MYH9 disorders, J. Thromb. Haemost., 11, 2071, 10.1111/jth.12406 · DOI
- Komatsu, 2007, The phosphorylation of myosin II at the Ser1 and Ser2 is critical for normal platelet-derived growth factor induced reorganization of myosin filaments, Mol. Biol. Cell, 18, 5081, 10.1091/mbc.e06-12-1076 · DOI
- Kopp, 2010, Glomerular pathology in autosomal dominant MYH9 spectrum disorders: what are the clues telling us about disease mechanism?, Kidney Int., 78, 130, 10.1038/ki.2010.82 · DOI
- Kopp, 2008, MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis, Nat. Genet., 40, 1175, 10.1038/ng.226 · DOI
- Kopp, 2011, APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy, J. Am. Soc. Nephrol., 22, 2129, 10.1681/ASN.2011040388 · DOI
- Kunishima, 2001, Mutations in the NMMHC-A gene cause autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly/Sebastian syndrome), Blood, 97, 1147, 10.1182/blood.V97.4.1147 · DOI
- Kunishima, 2003, Immunofluorescence analysis of neutrophil nonmuscle myosin heavy chain-A in MYH9 disorders: association of subcellular localization with MYH9 mutations, Lab. Investig., 83, 115, 10.1097/01.LAB.0000050960.48774.17 · DOI
- Kunishima, 2005, First description of somatic mosaicism in MYH9 disorders, Br. J. Haematol., 128, 360, 10.1111/j.1365-2141.2004.05323.x · DOI
- Kunishima, 2007, Haematological characteristics of MYH9 disorders due to MYH9 R702 mutations, Eur. J. Haematol., 78, 220, 10.1111/j.1600-0609.2006.00806.x · DOI
- Kunishima, 2009, Germinal mosaicism in MYH9 disorders: a family with two affected siblings of normal parents, Br. J. Haematol., 145, 260, 10.1111/j.1365-2141.2009.07584.x · DOI
- Kunishima, 2014, Somatic mosaicism in MYH9 disorders: the need to carefully evaluate apparently healthy parents, Br. J. Haematol., 165, 885, 10.1111/bjh.12797 · DOI
- Kelley, 2000, Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May-Hegglin anomaly, Nat. Genet., 26, 106, 10.1038/79069 · DOI
- Lalwani, 2008, Localization in stereocilia, plasma membrane, and mitochondria suggests diverse roles for NMHC-IIa within cochlear hair cells, Brain. Res., 1197, 13, 10.1016/j.brainres.2007.12.058 · DOI
- Lalwani, 2000, Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in nonmuscle myosin MYH9, Am. J. Hum. Genet., 67, 1121, 10.1016/S0002-9297(07)62942-5 · DOI
- Larson, 2006, A product of their environment: do megakaryocytes rely on extracellular cues for proplatelet formation?, Platelets, 17, 435, 10.1080/09537100600772637 · DOI
- Lin, 2017, LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration, Mol. Biol. Cell, 28, 1054, 10.1091/mbc.e15-04-0218 · DOI
- Li, 2006, The S100A4 metastasis factor regulates cellular motility via a direct interaction with myosin-IIA, Cancer Res., 66, 5173, 10.1158/0008-5472.CAN-05-3087 · DOI
- Li, 2010, S100A4 regulates macrophage chemotaxis, Mol. Biol. Cell, 21, 2598, 10.1091/mbc.e09-07-0609 · DOI
- Liao, 2017, LIM kinase 1 interacts with myosin-9 and alpha-actinin-4 and promotes colorectal cancer progression, Br. J. Cancer, 117, 563, 10.1038/bjc.2017.193 · DOI
- Ludowyke, 2006, Phosphorylation of nonmuscle myosin heavy chain IIA on Ser1917 is mediated by protein kinase C beta II and coincides with the onset of stimulated degranulation of RBL-2H3 mast cells, J. Immunol., 177, 1492, 10.4049/jimmunol.177.3.1492 · DOI
- Ma, 2012, In vivo studies on nonmuscle myosin II expression and function in heart development, Front. Biosci. (Landmark Ed.), 17, 545, 10.2741/3942 · DOI
- Ma, 2014, The role of vertebrate nonmuscle Myosin II in development and human disease, BioArchitecture, 4, 88, 10.4161/bioa.29766 · DOI
- Ma, 2010, Ablation of nonmuscle myosin II-B and II-C reveals a role for nonmuscle myosin II in cardiac myocyte karyokinesis, Mol. Biol. Cell, 21, 3952, 10.1091/mbc.e10-04-0293 · DOI
- Marigo, 2004, Correlation between the clinical phenotype of MYH9-related disease and tissue distribution of class II non-muscle myosin heavy chains, Genomics, 83, 1125, 10.1016/j.ygeno.2003.12.012 · DOI · Paper page
- Mhatre, 2006, Expression of Myh9 in the mammalian cochlea: localization within the stereocilia, J. Neurosci. Res., 84, 809, 10.1002/jnr.20993 · DOI
- Milton, 2011, Direct evidence for functional smooth muscle myosin II in the 10S self-inhibited monomeric conformation in airway smooth muscle cells, Proc. Natl. Acad. Sci. U. S. A., 108, 1421, 10.1073/pnas.1011784108 · DOI
- Miyagawa, 2013, Targeted exon sequencing successfully discovers rare causative genes and clarifies the molecular epidemiology of Japanese deafness patients, PLoS One, 8, 10.1371/journal.pone.0071381 · DOI
- Miyazaki, 2009, Identification of three in-frame deletion mutations in MYH9 disorders suggesting an important hot spot for small rearrangements in MYH9 exon 24, Eur. J. Haematol., 83, 230, 10.1111/j.1600-0609.2009.01274.x · DOI
- Moussavi, 1993, Phosphorylation of vertebrate nonmuscle and smooth muscle myosin heavy chains and light chains, Mol. Cell. Biochem., 127-128, 219, 10.1007/BF01076773 · DOI
- Neveling, 2013, A post-hoc comparison of the utility of sanger sequencing and exome sequencing for the diagnosis of heterogeneous diseases, Hum. Mutat., 34, 1721, 10.1002/humu.22450 · DOI
- Nishikawa, 1984, Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase, J. Biol. Chem., 259, 8808, 10.1016/S0021-9258(17)47225-5 · DOI
- Noris, 2013, Platelet size for distinguishing between inherited thrombocytopenias and immune thrombocytopenia: a multicentric, real life study, Br. J. Haematol., 162, 112, 10.1111/bjh.12349 · DOI
- Noris, 2014, Platelet diameters in inherited thrombocytopenias: analysis of 376 patients with all known disorders, Blood, 124, e4, 10.1182/blood-2014-03-564328 · DOI
- Odronitz, 2007, Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species, Genome Biol., 8, R196, 10.1186/gb-2007-8-9-r196 · DOI
- O'Seaghdha, 2011, The MYH9/APOL1 region and chronic kidney disease in European-Americans, Hum. Mol. Genet., 20, 2450, 10.1093/hmg/ddr118 · DOI
- Pecci, 2008, Position of nonmuscle myosin heavy chain IIA (NMMHC-IIA) mutations predicts the natural history of MYH9-related disease, Hum. Mutat., 29, 409, 10.1002/humu.20661 · DOI
- Pecci, 2008, Renin-angiotensin system blockade is effective in reducing proteinuria of patients with progressive nephropathy caused by MYH9 mutations (Fechtner-Epstein syndrome), Nephrol. Dial. Transplant., 23, 2690, 10.1093/ndt/gfn277 · DOI
- Pecci, 2009, Megakaryocytes of patients with MYH9-related thrombocytopenia present an altered proplatelet formation, Thromb. Haemost., 102, 90, 10.1160/TH09-01-0068 · DOI
- Pecci, 2010, Eltrombopag for the treatment of the inherited thrombocytopenia deriving from MYH9 mutations, Blood, 116, 5832, 10.1182/blood-2010-08-304725 · DOI
- Pecci, 2011, Mutations responsible for MYH9-related thrombocytopenia impair SDF-1-driven migration of megakaryoblastic cells, Thromb. Haemost., 106, 693, 10.1160/TH11-02-0126 · DOI
- Pecci, 2012, Alteration of liver enzymes is a feature of the MYH9-related disease syndrome, PLoS One, 7, e35986, 10.1371/journal.pone.0035986 · DOI
- Pecci, 2012, Short-term eltrombopag for surgical preparation of a patient with inherited thrombocytopenia deriving from MYH9 mutation, Thromb. Haemost., 107, 1188, 10.1160/TH12-01-0005 · DOI
- Pecci, 2014, MYH9-related disease: a novel prognostic model to predict the clinical evolution of the disease based on genotype-phenotype correlations, Hum. Mutat., 35, 236, 10.1002/humu.22476 · DOI
- Pecci, 2014, Cochlear implantation is safe and effective in patients with MYH9-related disease, Orphanet J. Rare Dis., 9, 100, 10.1186/1750-1172-9-100 · DOI
- Peterson, 1985, Fechtner syndrome—a variant of Alport's syndrome with leukocyte inclusions and macrothrombocytopenia, Blood, 65, 397, 10.1182/blood.V65.2.397.397 · DOI
- Raab, 2012, Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain, J. Cell Biol., 199, 669, 10.1083/jcb.201205056 · DOI
- Rai, 2017, Myosin IIA heavy chain phosphorylation mediates adhesion maturation and protrusion in three dimensions, J. Biol. Chem., 292, 3099, 10.1074/jbc.M116.733402 · DOI
- Ramagopal, 2013, Structure of the S100A4/myosin-IIA complex, BMC Struct. Biol., 13, 31, 10.1186/1472-6807-13-31 · DOI
- Ravid, 2014, The tumor suppressor Lgl1 regulates front-rear polarity of migrating cells, Cell Adhes. Migr., 8, 378, 10.4161/cam.29387 · DOI
- Rocca, 1993, Fechtner syndrome: report of a third family and literature review, Br. J. Haematol., 85, 423, 10.1111/j.1365-2141.1993.tb03193.x · DOI
- Sandquist, 2008, The C-terminal tail region of nonmuscle myosin II directs isoform-specific distribution in migrating cells, Mol. Biol. Cell, 19, 5156, 10.1091/mbc.e08-05-0533 · DOI
- Saposnik, 2014, Mutation spectrum and genotype-phenotype correlations in a large French cohort of MYH9-related disorders, Mol. Genet. Genomic Med., 2, 297, 10.1002/mgg3.68 · DOI
- Savoia, 2010, Heavy chain myosin 9-related disease (MYH9 -RD): neutrophil inclusions of myosin-9 as a pathognomonic sign of the disorder, Thromb. Haemost., 103, 826, 10.1160/TH09-08-0593 · DOI
- Schramek, 2014, Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas, Science, 343, 309, 10.1126/science.1248627 · DOI
- Sebé-Pedrós, 2014, Evolution and classification of myosins, a paneukaryotic whole-genome approach, Genome Biol. Evol., 6, 290, 10.1093/gbe/evu013 · DOI
- Sekine, 2010, Patients with Epstein-Fechtner syndromes owing to MYH9 R702 mutations develop progressive proteinuric renal disease, Kidney Int., 78, 207, 10.1038/ki.2010.21 · DOI
- Seri, 2000, Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes. The May-Heggllin/Fechtner Syndrome Consortium, Nat. Genet., 26, 103, 10.1038/79063 · DOI
- Seri, 2003, MYH9-related disease: May-Hegglin anomaly, Sebastian syndrome, Fechtner syndrome, and Epstein syndrome are not distinct entities but represent a variable expression of a single illness, Medicine (Baltimore), 82, 203, 10.1097/01.md.0000076006.64510.5c · DOI
- Shutova, 2014, Endogenous species of mammalian nonmuscle myosin IIA and IIB include activated monomers and heteropolymers, Curr. Biol., 24, 1958, 10.1016/j.cub.2014.07.070 · DOI
- Shutova, 2017, Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility, J. Cell Biol., 216, 2877, 10.1083/jcb.201705167 · DOI
- Sloan-Heggen, 2016, Comprehensive genetic testing in the clinical evaluation of 1119 patients with hearing loss, Hum. Genet., 135, 441, 10.1007/s00439-016-1648-8 · DOI
- Sellers, 2000, Myosins: a diverse superfamily, Biochim. Biophys. Acta, 2000, 3, 10.1016/S0167-4889(00)00005-7 · DOI
- Sellers, 1981, Reversible phosphorylation of smooth muscle myosin, heavy meromyosin, and platelet myosin, J. Biol. Chem., 256, 13137, 10.1016/S0021-9258(18)43018-9 · DOI
- Suzuki, 2013, Establishment of mouse model of MYH9 disorders: heterozygous R702C mutation provokes macrothrombocytopenia with leukocyte inclusion bodies, renal glomerulosclerosis and hearing disability, PLoS One, 8, 10.1371/journal.pone.0071187 · DOI
- Takeda, 2003, Ablation and mutation of nonmuscle myosin heavy chain II-B results in a defect in cardiac myocyte cytokinesis, Circ. Res., 93, 330, 10.1161/01.RES.0000089256.00309.CB · DOI
- Thon, 2012, Platelets: production, morphology and ultrastructure, Handb. Exp. Pharmacol., 210, 3, 10.1007/978-3-642-29423-5_1 · DOI
- Thon, 2012, Does size matter in platelet production?, Blood, 120, 1552, 10.1182/blood-2012-04-408724 · DOI
- Thon, 2012, Microtubule and cortical forces determine platelet size during vascular platelet production, Nat. Commun., 3, 852, 10.1038/ncomms1838 · DOI
- Totsukawa, 2000, Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts, J. Cell Biol., 150, 797, 10.1083/jcb.150.4.797 · DOI
- Tzur, 2010, Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene, Hum. Genet., 128, 345, 10.1007/s00439-010-0861-0 · DOI
- Verver, 2015, R705H mutation of MYH9 is associated with MYH9-related disease and not only with non-syndromic deafness DFNA17, Clin. Genet., 88, 85, 10.1111/cge.12438 · DOI
- Verver, 2016, Nonmuscle myosin heavy chain IIA mutation predicts severity and progression of sensorineural hearing loss in patients with MYH9-related disease, Ear Hear., 37, 112, 10.1097/AUD.0000000000000198 · DOI
- Vicente-Manzanares, 2009, Non-muscle myosin II takes centre stage in cell adhesion and migration, Nat. Rev. Mol. Cell Biol., 10, 778, 10.1038/nrm2786 · DOI
- Wang, 2010, Nonmuscle myosin II isoform and domain specificity during early mouse development, Proc. Natl. Acad. Sci. U. S. A., 107, 14645, 10.1073/pnas.1004023107 · DOI
- Wendt, 1999, Visualization of head-head interactions in the inhibited state of smooth muscle myosin, J. Cell Biol., 147, 1385, 10.1083/jcb.147.7.1385 · DOI
- Wu, 2013, Application of massively parallel sequencing to genetic diagnosis in multiplex families with idiopathic sensorineural hearing impairment, PLoS One, 8
- Yamanouchi, 2015, A novel MYH9 mutation in a patient with MYH9 disorders and platelet size-specific effect of romiplostim on macrothrombocytopenia, Ann. Hematol., 94, 1599, 10.1007/s00277-015-2416-x · DOI
- Ye, 2017, MicroRNA-647 targets SRF-MYH9 axis to suppress invasion and metastasis of gastric Cancer, Theranostics, 7, 3338, 10.7150/thno.20512 · DOI
- Zhang, 2012, Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A, Blood, 119, 238, 10.1182/blood-2011-06-358853 · DOI
- Zhu, 2017, MYBPH inhibits vascular smooth muscle cell migration and attenuates neointimal hyperplasia in a rat carotid balloon-injury model, Exp. Cell Res., 359, 154, 10.1016/j.yexcr.2017.07.036 · DOI
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Sun, J., Chen, F., She, L., Zeng, Y., Tang, H., Ye, B., Zheng, W., Xiong, L., Li, L., Li, L., et al. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2024.11.020 · Cited by 24
Peng, S., Stojkov, D., Gao, J., Oberson, K., Latzin, P., Casaulta, C., Yousefi, S., & Simon, H.-U. (2022) · PLOS Biology · doi:10.1371/journal.pbio.3001794 · Cited by 15
Metadata
- Authors
- Pecci, A., Ma, X., Savoia, A., & Adelstein, R. S.
- ORCID
- Pecci, Alessandro
- Venue
- Gene
- Publisher
- Elsevier BV
- Published
- 2018-07
- Volume
- 664
- Pages
- 152-167
- ISSN
- 0378-1119
- PMC
- PMC5970098
- Cited by
- 325
- References
- 0
- Language
- en
- Licence
- Funders
- Telethon Foundation (GGP17106)
- Fondazione IRCCS Policlinico San Matteo
- NHLBI
- NIH
- IRCCS Burlo Garofolo
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: MYH9: Structure, functions and role of non-muscle myosin IIA in human disease. https://app.cochat.ai/papers/10.1016/j.gene.2018.04.048
- The paper
- Pecci, A., Ma, X., Savoia, A., & Adelstein, R. S. (2018). MYH9: Structure, functions and role of non-muscle myosin IIA in human disease. Gene. https://doi.org/10.1016/j.gene.2018.04.048