Associations between posttraumatic stress disorder and hemoglobin A1C in low-income minority patients with diabetes
Open accessAbstract
Objective Posttraumatic Stress Disorder (PTSD) is prevalent among low-income minorities and is associated with poorer health. However, the association between PTSD and hemoglobin A1(C) (A1(C)) among patients with diabetes has not been fully described. The objective of this cross-sectional study was to evaluate associations between PTSD and A1(C) among low-income minorities with diabetes. Method Adults with diabetes were recruited from a network of primary care clinics. Data were obtained from surveys and electronic medical records. Lifetime PTSD symptoms were assessed using the Structured Clinical Interview-DSM-IV and depressive symptoms with the Patient Health Questionnaire-9. A1(C) was obtained from chart review. Results Of 103 adults analyzed, 12% had lifetime full PTSD and 12% had subthreshold PTSD. On backward stepwise logistic regression, patients with any PTSD symptoms were significantly more likely to have an A1(C) >7% compared to patients without symptoms (OR(adj) 2.98, 95% CI 1.04-8.52, P=.04). An A1(C) >7% also was associated with an interaction between PTSD symptoms and longer diabetes duration (P<.05). Conclusion In this cohort of low-income minorities with diabetes, lifetime PTSD symptoms were significantly associated with an A1(C) >7%.
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Anxiety is linked to worse glucose control.
“subsequent research in small cross-sectional studies has generally supported a link between anxiety and worse glucose control 112-114”
From Type 2 diabetes mellitus and psychological stress — a modifiable risk factor (2017) · cites this paper as [112]
The Results and Discussion (page unavailable in our copy) report that lifetime PTSD symptoms were associated with A1C >7%, indicating poorer glucose control in this cross-sectional sample. The study examined PTSD in low-income minority patients with type 2 diabetes, not anxiety generally, so it supports a narrower version of the claim. (LLM, conf=0.84)
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- Authors
- Miller, S. A., Mancuso, C. A., Boutin-Foster, C., Michelen, W., McLean-Long, C., Foote, B., & Charlson, M. E.
- Affiliations
- Montefiore Medical Center (US)
- Weill Cornell Medicine (US)
- Corresponding author
- Miller, Samantha A.
- Venue
- General Hospital Psychiatry
- Publisher
- Elsevier BV
- Published
- 2011-03
- Volume
- 33
- Issue
- 2
- Pages
- 116-122
- ISSN
- 0163-8343 (ISSN-L)
- PMC
- PMC5899900
- OpenAlex
- W1999609538
- Cited by
- 31
- References
- 41
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 4 · 2014: 3 · 2013: 1 · 2012: 3
- FWCI
- 3.45
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- General Hospital Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Georgia Clinical and Translational Science Alliance
- National Institutes of Health
- Agency for Healthcare Research and Quality (T32HS000066, 5 T32 HS000066)
- National Center for Research Resources (UL1RR025750)
- National Institute on Minority Health and Health Disparities (L60 MD003017)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Social Sciences › Psychology › Clinical Psychology › Migration, Health and Trauma
- Keywords
- post-traumatic stress disorder, HbA1c, diabetes mellitus, glycemic control, diabetes duration, depressive symptoms, subthreshold PTSD, primary care patients
- MeSH terms
- Aged, Cross-Sectional Studies, Diabetes Mellitus, Female, Glycated Hemoglobin, Humans, Male, Medical Audit, Middle Aged, Minority Groups, Poverty, Stress Disorders, Post-Traumatic, Logistic Models
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