Cited by 34Health and Medical Research ImpactsResearch, Science, and AcademiaBiotechnology and Related Fields

Geography of Genetics and Genomics Research Funding in Africa

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Coles, Eric, Mensah, George A.·2017·Global Heart

Abstract

An estimated U.S. $300 billion is spent each year on medical research. What proportion of this goes to genomics and genetics research in Africa? Until recently, this type of question was nearly impossible to answer. The World RePORT database, sponsored by the Heads of International Research Organizations (HIRO) and managed by the National Institutes of Health (NIH), provides a first attempt at answering questions on the distribution of research funding by geography and research organization. In this journal issue on the Human Heredity and Health in Africa (H3Africa), we explore the geography of biomedical research funding in the genomics field with special emphasis on Africa. Using World RePORT, we identified 185 research projects in genetics and genomics in Africa in 2015 with total funding exceeding U.S. $216 million. These numbers are likely incomplete and more efforts at collating data from funder organizations is needed. A comprehensive snapshot of funders' portfolios will be invaluable to research investigators and policy makers in the identification of research gaps and analysis of allocation priorities to facilitate evidence-based decision-making for public-research-funding organizations.

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  • The H3Africa Initiative has increased genomics research capacity in Africa through more than $216 million in funding from the NIH (USA) and Wellcome Trust (UK) for genetics research led by African investigators.

    “The most notable investment here comes from the Human Heredity and Health in Africa (H3Africa) Initiative, increasing genomics research capacity in Africa through more than $216 million in funding from the NIH (USA) and Wellcome Trust (UK) for genetics research led by African investigators55,74.”

    From Clinical use of current polygenic risk scores may exacerbate health disparities (2019) · cites this paper as [74]

    The Introduction says substantial NIH and Wellcome Trust investment in H3Africa gave genetics and genomics research in sub-Saharan Africa momentum. But the Results and Summary and Conclusions identify approximately $216 million as 2015 funding for 185 genetics and genomics projects across Africa, not funding for H3Africa alone; the paper also does not establish that those projects were led by African investigators. (LLM, conf=0.89)

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Research works printed but not linked: 4

  1. [1]Chakma J Sun GH Steinberg JD Sammut SM Jagsi R Asia’s ascent--global trends in biomedical R&D expenditures N Engl J Med 2014 370 1 3 6 24382062
  2. [3]Green ED Guyer MS Charting a course for genomic medicine from base pairs to bedside Nature 2011 470 7333 204 213 21307933
  3. [4]Collins FS Green ED Guttmacher AE Guyer MS A vision for the future of genomics research Nature 2003 422 6934 835 847 12695777
  4. [7]Mensah GA Peprah EK Sampson UK Cooper RS H3Africa comes of age Cardiovasc J Afr 2015 26 2 Suppl 1 S3 S5 PMC4547554 25962946

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Authors
Coles, E., & Mensah, G. A.
Affiliations
National Institutes of Health (US)
Corresponding author
Mensah, George A.
Venue
Global Heart
Published
2017-06-01
Volume
12
Issue
2
Pages
173
ISSN
  • 2211-8160 (ISSN-L)
  • 2211-8179
OpenAlex
W2752471688
Cited by
34
References
1
Citations by year
2025: 1 · 2024: 24 · 2023: 1 · 2022: 2 · 2020: 2 · 2019: 2 · 2018: 2
FWCI
1.54
Type
journal article
Language
en
Open access
Locations
  • Global Heart (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (Z99 HL999999)
  • Fogarty International Center
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
  • Social Sciences › Decision Sciences › Information Systems and Management › Research, Science, and Academia
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Biotechnology and Related Fields
Keywords
research funding, genomics, genetic research, Africa, H3Africa, biomedical research funding, research funding allocation, research gaps, science policy, research funding agencies
MeSH terms
Africa, Capital Financing, Humans, Databases, Factual, Genomics, Biomedical Research

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