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Cited by 326Atrial Fibrillation Management and OutcomesCardiac Arrhythmias and TreatmentsCardiac pacing and defibrillation studies

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Temporal relationship of atrial tachyarrhythmias, cerebrovascular events, and systemic emboli based on stored device data: A subgroup analysis of TRENDS

Daoud, Emile G., Glotzer, Taya V., Wyse, D. George, Ezekowitz, Michael D., Hilker, Christopher, Koehler, Jodi, Ziegler, Paul D.·2011·Heart Rhythm
DOI 10.1016/j.hrthm.2011.04.022
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Abstract

Background The temporal relationship between atrial tachyarrhythmias (atrial tachycardia [AT] and atrial fibrillation [AF]) and cerebrovascular events/systemic emboli (CVE/SE) is unknown.Objective The purpose of this study was to evaluate this relationship using stored AT/AF diagnostic data from implanted devices in patients with and those without AF.Methods The TRENDS study enrolled 2,486 patients with an indication for an implantable device, at least one stroke risk factor, and available device data. The current study includes the subgroup of 40 (1.6%) patients enrolled in TRENDS who experienced CVE/SE.Results AT/AF was detected prior to CVE/SE in 20 (50%) of 40 patients. Other than average and maximum daily AT/AF burden and duration of device monitoring prior to CVE/SE, no statistically significant differences were found between patients with and those without AT/AF prior to CVE/SE. For the 20 patients with AT/AF detected prior to CVE/SE, 9 (45%) did not have any AT/AF in the 30 days prior to CVE/SE. Therefore, 29 (73%) of 40 patients with CVE/SE had zero AT/AF burden within 30 days prior to CVE/SE. Fourteen (70%) of the 20 patients with AT/AF detected prior to CVE/SE were not in AT/AF at diagnosis of CVE/SE. The last episode of AT/AF in these 14 patients was 168 ± 199 days (range 3-642 days) before CVE/SE.Conclusion The majority of CVE/SE in this population did not occur proximal to recent AT/AF episodes. These data imply that the mechanisms of CVE/SE in patients with implantable devices may importantly involve mechanisms other than cardioembolism due to atrial tachyarrhythmias.

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Metadata

Authors
Daoud, E. G., Glotzer, T. V., Wyse, D. G., Ezekowitz, M. D., Hilker, C., Koehler, J., & Ziegler, P. D.
Affiliations
  • The Ohio State University Wexner Medical Center (US)
  • Hackensack University Medical Center (US)
  • Libin Cardiovascular Institute of Alberta (CA)
  • Lankenau Institute for Medical Research (US)
  • Medtronic (United States) (US)
Corresponding author
Daoud, Emile G.
ORCID
Venue
Heart Rhythm
Publisher
Elsevier BV
Published
2011-09
Volume
8
Issue
9
Pages
1416-1423
ISSN
1547-5271 (ISSN-L)
DOI
10.1016/j.hrthm.2011.04.022
OpenAlex
W2020006237
Cited by
326
References
33
Citations by year
2026: 8 · 2025: 10 · 2024: 20 · 2023: 18 · 2022: 20 · 2021: 28 · 2020: 20 · 2019: 19 · 2018: 31 · 2017: 38 · 2016: 39 · 2015: 26 · 2014: 24 · 2013: 10 · 2012: 11
FWCI
10.52
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Heart Rhythm (publishedVersion)
  • PubMed (publishedVersion)
Funders
Medtronic
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Keywords
atrial tachyarrhythmia, atrial fibrillation, atrial tachycardia, cerebrovascular events, systemic embolism, stroke, temporal relations, cardiac implantable electronic devices, device monitoring, cardiac embolism
MeSH terms
Aged, Aged, 80 and over, Atrial Fibrillation, Cardiac Pacing, Artificial, Embolism, Female, Humans, Male, Middle Aged, Product Surveillance, Postmarketing, Prospective Studies, Tachycardia, Ectopic Atrial, Information Storage and Retrieval, Defibrillators, Implantable, Brain Infarction

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