Cited by 184Atrial Fibrillation Management and OutcomesCardiovascular and Diving-Related ComplicationsCardiac Arrhythmias and Treatments

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Association between incomplete surgical ligation of left atrial appendage and stroke and systemic embolization

Aryana, Arash, Singh, Steve K., Singh, Sheldon M., Gearoid O’Neill, P., Bowers, Mark R., Allen, Shelley L., Lewandowski, Sammi L., Vierra, Eleanor C., d’Avila, André·2015·Heart Rhythm

DOI 10.1016/j.hrthm.2015.03.028

Open this paper in CoChat — free account

Abstract

Background Surgical exclusion of the left atrial appendage (LAA) can frequently yield incomplete closure.Objective We evaluated the ischemic stroke/systemic embolization (SSE) risk in patients with atrial fibrillation (AF) and complete LAA closure (cLAA) vs incompletely surgically ligated LAA (ISLL) and LAA stump after surgical suture ligation.Methods Seventy-two patients (CHA2DS2-VASc score 4.1 ± 1.9) underwent surgical LAA ligation in conjunction with mitral valve/AF surgery and postoperative LAA evaluation using computerized tomographic angiography.Results Overall, cLAA was detected in 46 of 72 patients (64%), ISLL in 17 patients (24%), and LAA stump in 9 patients (12%). The incidences of oral anticoagulation (OAC) and recurrent AF were similar among the 3 groups during 44 ± 19 months of follow-up. SSE occurred in 2% of patients with cLAA vs 24% with ISLL and 0% with LAA stump (P = .006). None of the patients with SSE were receiving OAC, and all had recurrent AF during follow-up. Additionally, patients with SSE exhibited a significantly smaller ISLL neck diameter (2.8 ± 1.0 vs 7.1 ± 2.1 mm; P = .002). The annualized SSE risk was 1.9% (entire cohort), 6.5% (ISLL patients), 14.4% (ISLL patients not receiving OAC), and 19.0% (ISLL neck diameter ≤5.0 mm) per 100 patient-years of follow-up. The latter risk was nearly 5 times greater than predicted by conventional risk-stratification schemes. Moreover, ISLL emerged as an independent predictor of SSE in univariate analyses and as the sole predictor of SSE in a multivariate analysis.Conclusion In patients with AF, ISLL is a predictor of SSE, independent of conventional risk stratification schemes. Consequently, OAC should be strongly considered in this high-risk cohort.

Integrity signals

Registry

Crossref · 10.1016/j.hrthm.2015.03.028

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.05.007 · Cited by 2,245
Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial
Holmes, D. R., Reddy, V. Y., Turi, Z. G., Doshi, S. K., Sievert, H., Buchbinder, M., Mullin, C. M., & Sick, P. B. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61343-x · Cited by 2,242
Prospective Randomized Evaluation of the Watchman Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation Versus Long-Term Warfarin Therapy
Holmes, D. R., Kar, S., Price, M. J., Whisenant, B. K., Sievert, H., Doshi, S. K., Huber, K., & Reddy, V. Y. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.04.029 · Cited by 1,874
2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.190748 · Cited by 1,128
Does the Left Atrial Appendage Morphology Correlate With the Risk of Stroke in Patients With Atrial Fibrillation?
Biase, L. D., Santangeli, P., Anselmino, M., Mohanty, P. K., Salvetti, I., Gili, S., Horton, R., Sánchez, J., Bai, R., Mohanty, S., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.04.032 · Cited by 876
NHLBI funding policies. Enhancing stability, predictability, and cost control.
Lenfant, C. L. (1994) · Circulation · doi:10.1161/01.cir.90.1.1 · Cited by 763
Success of Surgical Left Atrial Appendage Closure
KANDERIAN, A. S., Gillinov, A. M., Pettersson, G., Blackstone, E. H., & Klein, A. L. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.03.067 · Cited by 551
The Clinical Impact of Incomplete Left Atrial Appendage Closure With the Watchman Device in Patients With Atrial Fibrillation
Viles-González, J. F., Kar, S., Douglas, P. S., Dukkipati, S. R., Feldman, T. E., Horton, R., Holmes, D. R., & Reddy, V. Y. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.11.028 · Cited by 545
Left Atrial Appendage Occlusion Study (LAAOS): results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke
Healey, J. S., Crystal, E., Lamy, A., Teoh, K., Semelhago, L., Hohnloser, S. H., Cybulsky, I., Abouzahr, L., Sawchuck, C., Carroll, S., et al. (2005) · American Heart Journal · doi:10.1016/j.ahj.2004.09.054 · Cited by 496
Surgical left atrial appendage ligation is frequently incomplete: a transesophageal echocardiographic study
Katz, E. S., Tsiamtsiouris, T., Applebaum, R. M., Schwartzbard, A. Z., Tunick, P. A., & Kronzon, I. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00765-8 · Cited by 392

Flagged first, then by citations

Show all 27 references

Research works printed but not linked: 1

Labovitz, 1994, Transesophageal echocardiography in patients with unexplained cerebral ischemia: multicenter findings, Circulation, 90, 1

Sorted by citations

2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)
Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J. J., Blomström‐Lundqvist, C., Boriani, G., Castella, M., Dan, G.-A., Dilaveris, P., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa612 · Cited by 10,550
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P. F., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castellà, M., Diener, H., Heidbüchel, H., Hendriks, J., et al. (2016) · EP Europace · doi:10.1093/europace/euw295 · Cited by 6,438
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418
2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
Joglar, J. A., Chung, M. K., Armbruster, A. L., Benjamin, E. J., Chyou, J. Y., Cronin, E. M., Deswal, A. M., Eckhardt, L. L., Goldberger, Z. D., Gopinathannair, R., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001193 · Cited by 3,072
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw313 · Cited by 1,403
Antithrombotic Therapy for Atrial Fibrillation
Lip, G. Y. H., Banerjee, A., Boriani, G., Chiang, C. E., Fargo, R. A., Freedman, B., Lane, D. A., Ruff, C. T., Turakhia, M. P., Werring, D. J., et al. (2018) · CHEST Journal · doi:10.1016/j.chest.2018.07.040 · Cited by 963
2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation
Joglar, J. A., Chung, M. K., Armbruster, A. L., Benjamin, E. J., Chyou, J. Y., Cronin, E. M., Deswal, A., Eckhardt, L. L., Goldberger, Z. D., Gopinathannair, R., et al. (2024) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.08.017 · Cited by 933
National Heart Foundation of Australia and the Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Diagnosis and Management of Atrial Fibrillation 2018
Brieger, D. B., Amerena, J. V., Attia, J., Bajorek, B. V., Chan, K. H., Connell, C., Freedman, B., Ferguson, C., Hall, T. L., Haqqani, H. M., et al. (2018) · Heart Lung and Circulation · doi:10.1016/j.hlc.2018.06.1043 · Cited by 335
Amulet or Watchman Device for Percutaneous Left Atrial Appendage Closure: Primary Results of the SWISS-APERO Randomized Clinical Trial
Galea, R., MARCO, F. D., Meneveau, N. F., Aminian, A., Anselme, F., Gräni, C., Huber, A. T., Teíger, E., Iriart, X., Bosombo, F. B., et al. (2021) · Circulation · doi:10.1161/circulationaha.121.057859 · Cited by 152
Impact of Left Atrial Appendage Closure During Cardiac Surgery on the Occurrence of Early Postoperative Atrial Fibrillation, Stroke, and Mortality
Melduni, R. M., Schaff, H. V., Lee, H.-C., Gersh, B. J., Noseworthy, P. A., Bailey, K. R., Ammash, N. M., Cha, S. S., Fatema, K., Wysokiński, W. E., et al. (2016) · Circulation · doi:10.1161/circulationaha.116.021952 · Cited by 151
Impact of Peridevice Leak on 5-Year Outcomes After Left Atrial Appendage Closure
Dukkipati, S. R., Holmes, D. R., Doshi, S. K., Kar, S., Singh, S. M., Gibson, D. N., Price, M. J., Natale, A., Mansour, M., Sievert, H., et al. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2022.04.062 · Cited by 140
Self-citation
Atrial Fibrillation Occurring During Acute Hospitalization: A Scientific Statement From the American Heart Association
Chyou, J. Y., Barkoudah, E., Dukes, J. W., Goldstein, L. B., Joglar, J. A., Lee, A. M., Lubitz, S. A., Marill, K. A., Sneed, K., Streur, M. M., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001133 · Cited by 127
Epicardial left atrial appendage AtriClip occlusion reduces the incidence of stroke in patients with atrial fibrillation undergoing cardiac surgery
Caliskan, E., Sahin, A., Yılmaz, M., Seifert, B., Hinzpeter, R., Alkadhi, H., Cox, J. L., Holubec, T., Reser, D., Falk, V., et al. (2017) · EP Europace · doi:10.1093/europace/eux211 · Cited by 121
Residual leaks following percutaneous left atrial appendage occlusion and outcomes: a meta-analysis
Samaras, A., Papazoglou, Α. S., Balomenakis, C., Bekiaridou, Α., Moysidis, D. V., Patsiou, V., Orfanidis, A., Giannakoulas, G. A., Kassimis, G., Fragakis, N., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad828 · Cited by 104
European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on risk assessment in cardiac arrhythmias: use the right tool for the right outcome, in the right population
Nielsen, J. C., Lin, Y., Figueiredo, M. J. D. O., Shamloo, A. S., Alfie, A., Bovéda, S., Dagres, N., Toro, D. D., Eckhardt, L. L., Ellenbogen, K. A., et al. (2020) · Journal of Arrhythmia · doi:10.1002/joa3.12338 · Cited by 106
European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on risk assessment in cardiac arrhythmias: use the right tool for the right outcome, in the right population
Nielsen, J. C., Lin, Y.-J., de Oliveira Figueiredo, M. J., Sepehri Shamloo, A., Alfie, A., Boveda, S., Dagres, N., Di Toro, D., Eckhardt, L. L., Ellenbogen, K., et al. (2020) · EP Europace · doi:10.1093/europace/euaa065 · Cited by 98
Left Atrial Appendage Occlusion for The Unmet Clinical Needs of Stroke Prevention in Nonvalvular Atrial Fibrillation
Holmes, D. R., Alkhouli, M. A., & Reddy, V. Y. (2019) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2018.09.025 · Cited by 90
JCS/JSCVS 2018 Guideline on Revascularization of Stable Coronary Artery Disease
Nakamura, M., Yaku, H., Ako, J., Arai, H., Asai, T., Chikamori, T., Daida, H., Doi, K., Fukui, T., Ito, T., et al. (2022) · Institutional Repositories DataBase (IRDB) · doi:10.1253/circj.cj-20-1282 · Cited by 70
Stroke Prevention in Nonvalvular Atrial Fibrillation
Alkhouli, M. A., Noseworthy, P. A., Rihal, C. S., & Holmes, D. R. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.04.013 · Cited by 70
Residual leaks following percutaneous left atrial appendage occlusion: assessment and management implications
Raphael, C. E., Friedman, P., Saw, J., Pislaru, S. V., Munger, T. M., & Holmes, D. R. (2017) · EuroIntervention · doi:10.4244/eij-d-17-00469 · Cited by 68
Angiographic Efficacy of the Atriclip Left Atrial Appendage Exclusion Device Placed by Minimally Invasive Thoracoscopic Approach
Ellis, C. R., Aznaurov, S. G., Patel, N., Williams, J. R., Sandler, K. L., Hoff, S. J., Ball, S. K., Whalen, S. P., & Carr, J. J. (2017) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2017.03.008 · Cited by 63
First Experience of Transcatheter Leak Occlusion With Detachable Coils Following Left Atrial Appendage Closure
Rocca, D. G. D., Horton, R., Biase, L. D., Bassiouny, M., Al‐Ahmad, A., Mohanty, S., Gasperetti, A., Natale, V. N., Trivedi, C. G., Gianni, C., et al. (2020) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2019.10.022 · Cited by 62
Patient-specific design of a soft occluder for the left atrial appendage
Robinson, S. S., Alaie, S., Sidoti, H., Augé, J., Baskaran, L., Avilés-Fernández, K., Hollenberg, S., Shepherd, R. F., Min, J. K., Dunham, S. N., et al. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-017-0180-z · Cited by 60
Clinical Implications of Leaks Following Left Atrial Appendage Ligation With the LARIAT Device
Gianni, C., Biase, L. D., Trivedi, C. G., Mohanty, S., Gökoğlan, Y., Günes, M. F., Bai, R., Al‐Ahmad, A., Burkhardt, J. D., Horton, R., et al. (2016) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2016.01.038 · Cited by 56
Cardiovascular Therapies Targeting Left Atrial Appendage
Turagam, M. K., Velagapudi, P., Kar, S., Holmes, D. R., Reddy, V. Y., Refaat, M. M., Biase, L. D., Al‐Ahmed, A., Chung, M. K., Lewalter, T., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.05.048 · Cited by 56
Five-year outcomes in cardiac surgery patients with atrial fibrillation undergoing concomitant surgical ablation versus no ablation. The long-term follow-up of the PRAGUE-12 Study
Osmancik, P. P., Budera, P., Talavera, D., Hlavička, J., Heřman, D., Holy, J., Červinka, P., Šmı́d, J., Hanak, P., Hatala, R., et al. (2019) · Heart Rhythm · doi:10.1016/j.hrthm.2019.05.001 · Cited by 51
Management of atrial fibrillation: two decades of progress — a scientific statement from the European Cardiac Arrhythmia Society
Lévy, S., Steinbeck, G., Santini, L., Näbauer, M., Penela, D., Kantharia, B. K., Saksena, S. V., & Cappato, R. (2022) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-022-01195-z · Cited by 50
Risk of thromboembolic events after percutaneous left atrial appendage ligation in patients with atrial fibrillation: Long-term results of a multicenter study
Mohanty, S., Gianni, C., Trivedi, C. G., Gadiyaram, V. K., Rocca, D. G. D., MacDonald, B. C., Horton, R., Al‐Ahmad, A., Gibson, D. N., Price, M. J., et al. (2019) · Heart Rhythm · doi:10.1016/j.hrthm.2019.08.003 · Cited by 49
Cardiovascular Outcomes With Surgical Left Atrial Appendage Exclusion in Patients With Atrial Fibrillation Who Underwent Valvular Heart Surgery (from the National Inpatient Sample Database)
Elbadawi, A., Olorunfemi, O. E., Ogunbayo, G. O., Saad, M. S., Elgendy, I. Y., Arif, Z., Badran, H., Saheed, D., Ahmed, H. M. A., & Rao, M. C. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2017.03.037 · Cited by 46
Interventional and surgical occlusion of the left atrial appendage
Caliskan, E., Cox, J. L., Holmes, D. R., Meier, B., Lakkireddy, D., Falk, V., Salzberg, S. P., & Emmert, M. Y. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2017.107 · Cited by 45
European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on risk assessment in cardiac arrhythmias: use the right tool for the right outcome, in the right population
Nielsen, J. C., Lin, Y., Figueiredo, M. J. D. O., Shamloo, A. S., Alfie, A., Bovéda, S., Dagres, N., Toro, D. D., Eckhardt, L. L., Ellenbogen, K. A., et al. (2020) · Heart Rhythm · doi:10.1016/j.hrthm.2020.05.004 · Cited by 42
Nonpharmacological Management of Atrial Fibrillation in Patients at High Intracranial Hemorrhage Risk
Gurol, M. E. (2017) · Stroke · doi:10.1161/strokeaha.117.017081 · Cited by 36
State of the Art in Left Atrial Appendage Occlusion
Garg, J., Kabra, R., Gopinathannair, R., Biase, L. D., Wang, D. D., Saw, J., Hahn, R. T., Freeman, J. V., Ellis, C. R., & Lakkireddy, D. (2025) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2024.10.024 · Cited by 35
Thoracoscopic stapler-and-loop technique for left atrial appendage closure in nonvalvular atrial fibrillation: Mid-term outcomes in 201 patients
Ohtsuka, T., Nonaka, T., Hisagi, M., Ninomiya, M., Masukawa, A., & Ota, T. (2018) · Heart Rhythm · doi:10.1016/j.hrthm.2018.05.026 · Cited by 35
Incidence and characteristics of left atrial appendage stumps after device-enabled epicardial closure
Caliskan, E., Eberhard, M., Falk, V., Alkadhi, H., & Emmert, M. Y. (2019) · Interactive Cardiovascular and Thoracic Surgery · doi:10.1093/icvts/ivz176 · Cited by 34
Residual echocardiographic and computed tomography findings after thoracoscopic occlusion of the left atrial appendage using the AtriClip PRO device
Osmancik, P. P., Budera, P., Veselá, J., Heřman, D., Petr, R., Fojt, R., & Straka, Z. (2017) · Interactive Cardiovascular and Thoracic Surgery · doi:10.1093/icvts/ivx427 · Cited by 33
Leaks after Left Atrial Appendage Closure: Ignored or Neglected?
Jang, S., Wong, S. C., & Mosadegh, B. (2021) · Cardiology · doi:10.1159/000513901 · Cited by 32
Safety and feasibility of peri-device leakage closure after LAAO: an international, multicentre collaborative study
Piayda, K., Sievert, K., Rocca, D. G. D., Adeola, O. G., Alkhouli, M., Yoo, D., Benito-González, T., Cruz-González, I., Galea, R., Skurk, C., et al. (2021) · EuroIntervention · doi:10.4244/eij-d-21-00286 · Cited by 31
Guía ESC 2020 sobre el diagnóstico y tratamiento de la fibrilación auricular, desarrollada en colaboración de la European Association of Cardio-Thoracic Surgery (EACTS)
Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J. J., Blomström‐Lundqvist, C., Boriani, G., Castellà, M., Dan, G., Dilaveris, P., et al. (2021) · Revista Española de Cardiología · doi:10.1016/j.recesp.2020.10.022 · Cited by 34
Left atrial appendage shape impacts on the left atrial flow hemodynamics: A numerical hypothesis generating study on two cases
Alinezhad, L., Ghalichi, F., Ahmadlouydarab, M., & Chenaghlou, M. (2021) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2021.106506 · Cited by 27
5-Year Experience of In-Hospital Outcomes After Percutaneous Left Atrial Appendage Closure in Germany
Hobohm, L., von Bardeleben, R. S., Ostad, M. A., Wenzel, P., Münzel, T. F., Gori, T., & Keller, K. (2019) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2019.04.002 · Cited by 27
Impact of Left Atrial Appendage Exclusion on Cardiovascular Outcomes in Patients With Atrial Fibrillation Undergoing Coronary Artery Bypass Grafting (From the National Inpatient Sample Database)
Elbadawi, A., Ogunbayo, G. O., Elgendy, I. Y., Olorunfemi, O. E., Saad, M. S., Ha, L. D., Alotaki, E., Baig, B., Abuzaid, A., Shahin, H. I., et al. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2017.06.025 · Cited by 24
Safety and feasibility of peri-device leakage closure after LAAO: an international, multicentre collaborative study
Piayda, K., Sievert, K., Rocca, D. G. D., Adeola, O., Alkhouli, M. A., Yoo, D. H., Benito‐González, T., Cruz‐González, I., Galea, R., Skurk, C., et al. (2021) · doi:10.48350/163276 · Cited by 23
Surgical management of the left atrial appendage: a must or a myth?
Hanke, T. (2018) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezy088 · Cited by 23
Efficacy of four different left atrial appendage closure techniques during cardiac surgery—A transesophageal echocardiography follow-up study
Petersen, J., Böning, H., Yildirim, S., Alassar, Y., Yıldırım, Y., Bazhanov, I., Sinning, C., Reichenspurner, H. C., & Pecha, S. (2024) · JTCVS Techniques · doi:10.1016/j.xjtc.2024.05.007 · Cited by 22
Epicardial left atrial appendage clip occlusion in patients with atrial fibrillation during minimally invasive cardiac surgery
Rhee, Y., Park, S. J., & Lee, J. W. (2021) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2021.10.032 · Cited by 22
Evaluation of Multimodality LAA Leak Closure Methods Following Incomplete Occlusion
Charate, R. A., Ahmed, A., Rocca, D. G. D., Bloom, S., Garg, J., Pothineni, N. V. K., Biase, L. D., Turagam, M. K., Gopinathannair, R., Horton, R., et al. (2022) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2022.08.034 · Cited by 21
Combination of ablation and left atrial appendage closure as “One‐stop” procedure in the treatment of atrial fibrillation: Current status and future perspective
He, B., Jiang, L., Hao, Z., Wang, H., & Miao, Y. (2021) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.14201 · Cited by 21
Feasibility of left atrial appendage device closure following chronically failed surgical ligation
Ellis, C. R., Metawee, M., Piana, R. N., Bennett, J. M., Pretorius, M., & Deegan, R. (2018) · Heart Rhythm · doi:10.1016/j.hrthm.2018.07.017 · Cited by 21
Radiofrequency Energy Applications Targeting Significant Residual Leaks After Watchman Implantation
Rocca, D. G. D., Murtaza, G., Biase, L. D., Akella, K., Krishnan, S., Magnocavallo, M., Mohanty, S., Gianni, C., Trivedi, C. G., Lavalle, C., et al. (2021) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2021.06.002 · Cited by 20
Diretriz Brasileira de Fibrilação Atrial – 2025
Cintra, F. D., Pisani, C. F., Rezende, A. G. D. S., Henz, B. D., Armaganijan, L., Pimentel, M., Lópes, R. D., do Nascimento, T. A., Lorga-Filho, A. M., de Albuquerque, A., et al. (2025) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20250618 · Cited by 21
Systematic review and meta-analysis of left atrial appendage closure's influence on early and long-term mortality and stroke
Kowalewski, M., Święczkowski, M., Kuźma, Ł., Maesen, B. A. E., Dąbrowski, E. J., Matteucci, M., Batko, J., Litwinowicz, R. A., Kowalówka, A. R., Wańha, W., et al. (2024) · JTCVS Open · doi:10.1016/j.xjon.2024.02.022 · Cited by 17
Percutaneous left atrial appendage closure
Jazayeri, M., Vuddanda, V. L. K., Parikh, V. K., & Lakkireddy, D. (2016) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000367 · Cited by 17
Use of a Novel Septal Occluder Device for Left Atrial Appendage Closure in Patients With Postsurgical and Postlariat Leaks or Anatomies Unsuitable for Conventional Percutaneous Occlusion
Rocca, D. G. D., Horton, R., Tarantino, N. M., Niekerk, C. J. V., Trivedi, C. G., Chen, Q., Mohanty, S., Anannab, A., Murtaza, G., Akella, K., et al. (2020) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.120.009227 · Cited by 17
Design and Rationale of the Swiss-Apero Randomized Clinical Trial: Comparison of Amplatzer Amulet vs Watchman Device in Patients Undergoing Left Atrial Appendage Closure
Galea, R., MARCO, F. D., Aminian, A., Meneveau, N. F., Anselme, F., Gräni, C., Huber, A. T., Teíger, E., Iriart, X., Angelillis, M., et al. (2021) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-020-10095-4 · Cited by 17
PREventive left atrial appenDage resection for the predICtion of fuTure atrial fibrillation: design of the PREDICT AF study
van den Berg, N. W. E., Neefs, J., Berger, W. R., Boersma, L. V. A., van Boven, W. J., van Putte, B. P., Kaya, A., Kawasaki, M., Driessen, A. H. G., & de Groot, J. R. (2019) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000000868 · Cited by 16
Computational Flow Dynamic Analysis in Left Atrial Appendage Thrombus Formation Risk: A Review
Valvez, S., Santos, M. O., Piedade, A. P., Gonçalves, L. M. M., & Amaro, A. M. (2023) · Applied Sciences · doi:10.3390/app13148201 · Cited by 15
Left Atrial Appendage Occlusion: A Narrative Review
Alsagheir, A., Koziarz, A., Belley‐Côté, E. P., & Whitlock, R. P. (2019) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2019.01.054 · Cited by 15
Clinical Implications and Management Strategies for Left Atrial Appendage Leaks
Salwan, A. S., Rocca, D. G. D., Anannab, A., Mohanty, S., Akella, K., Murtaza, G., Trivedi, C. G., Gianni, C., Chen, Q., Bassiouny, M., et al. (2020) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2019.11.010 · Cited by 15
Modification of the left atrial appendage and its role in stroke risk reduction with non-valvular atrial fibrillation
Rashid, H. N. Z., & Layland, J. J. (2020) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2020.100688 · Cited by 15
Different Techniques of Surgical Left Atrial Appendage Closure and Their Efficacy: A Systematic Review
D’Abramo, M., Romiti, S., Saltarocchi, S., Saade, W., Spunticchia, F., Bruno, N., Peruzzi, M., Miraldi, F., Frati, G., Greco, E., et al. (2023) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2406184 · Cited by 14
Surgical techniques for left atrial appendage exclusion
Salzberg, S. P., Emmert, M. Y., & Caliskan, E. (2017) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s00399-017-0532-0 · Cited by 14
Peri-Device Leaks after Percutaneous Left Atrial Appendage Closure: Clinical Significance and Unmet Diagnostic Needs
Albaghdadi, M. S., Kadlec, A. O., Adler, A., Siddiqui, U., Romanov, A., Kück, K., Sievert, H., Leon, M. B., & Vahl, T. P. (2020) · Structural Heart · doi:10.1080/24748706.2020.1817642 · Cited by 14
The relationship between incomplete surgical obliteration of the left atrial appendage and thromboembolic events after mitral valve surgery (from the ISOLATE Registry)
Güner, A., Kalçık, M., Gündüz, S., Gürsoy, M. O., Güner, E. G., Ulutaş, A. E., Kalkan, S., Onan, B., Bayam, E. M., Ertük, M., et al. (2020) · Journal of Thrombosis and Thrombolysis · doi:10.1007/s11239-020-02291-5 · Cited by 14
Incomplete surgical ligation of the left atrial appendage—time for a new look at an old problem
Aryana, A., & Bhaskar, R. (2017) · Annals of Translational Medicine · doi:10.21037/atm.2017.02.17 · Cited by 14
Self-citation
Long-term thrombus-free left atrial appendage occlusion via magnetofluids
Wang, S., Ju, W., Zhuang, D., Chen, Z., Zhao, D., Huang, S., Wang, T., Cai, M., Liu, S., Fu, S., et al. (2026) · Nature · doi:10.1038/s41586-025-10091-1 · Cited by 13
Incomplete Closure of the Left Atrial Appendage: Implication and Management
Aryana, A., & d’Ávila, A. (2016) · Current Cardiology Reports · doi:10.1007/s11886-016-0765-2 · Cited by 13
Self-citation
Surgical left atrial appendage occlusion in patients with atrial fibrillation undergoing mechanical heart valve replacement
Zheng, Y., Rao, C., Chen, S., He, L., Hou, J., & Zheng, Z. (2020) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000967 · Cited by 13
Evidence and Challenges in Left Atrial Appendage Management
Yamamoto, T., Endo, D., Matsushita, S., Shimada, A., Nakanishi, K., Asai, T., & Amano, A. (2021) · Annals of Thoracic and Cardiovascular Surgery · doi:10.5761/atcs.ra.21-00040 · Cited by 13
Does left atrial appendage ligation during coronary bypass surgery decrease the incidence of postoperative stroke?
Juo, Y., Bailey, K. L., Seo, Y., Aguayo, E., & Benharash, P. (2018) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2018.02.089 · Cited by 12
Imaging for Percutaneous Left Atrial Appendage Closure: A Contemporary Review
Ramchand, J., Harb, S. C., Miyasaka, R., Kanj, M. H., Saliba, W. I., & Jaber, W. A. (2019) · Structural Heart · doi:10.1080/24748706.2019.1643957 · Cited by 12
2018 KHRS Guidelines for Stroke Prevention Therapy in Korean Patients with Nonvalvular Atrial Fibrillation
Lee, J., Joung, B., Cha, M., Lee, J. H., Lim, W., Kim, T., Shin, S. Y., Uhm, J., Lim, H. E., Kim, J., et al. (2018) · Korean Journal of Medicine · doi:10.3904/kjm.2018.93.2.87.e1 · Cited by 11
Transcatheter embolic coils to treat peridevice leaks after left atrial appendage closure
Musikantow, D. R., Shivamurthy, P., Croft, L. B., Kawamura, I., Turagam, M. K., Whang, W., Dukkipati, S. R., Goldman, M. E., & Reddy, V. Y. (2021) · Heart Rhythm · doi:10.1016/j.hrthm.2021.01.030 · Cited by 11
Surgical and percutaneous left atrial appendage intervention: silent cerebral embolism considerations
Wang, Z., Wang, K., Lu, S., Zhang, L., Li, M., Ju, W., Ni, B., Gu, W., Shao, Y., & Chen, M. (2023) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezad074 · Cited by 11
Does Left Atrial Appendage Amputation During Routine Cardiac Surgery Reduce Future Atrial Fibrillation and Stroke?
Domínguez, H., Madsen, C. V., Westh, O. N. H., Pallesen, P. A., Carranza, C. L., Irmukhamedov, A., & Park-Hansen, J. (2018) · Current Cardiology Reports · doi:10.1007/s11886-018-1033-4 · Cited by 11
Left atrial appendage orifice diameter measured with trans-esophageal echocardiography is independently related with peri-device leakage after Watchman device implantation
Chen, Y., Zhang, Y., Chen, X., Huang, W., Su, X., Su, X., & Chen, Y. (2019) · International journal of cardiac imaging · doi:10.1007/s10554-019-01625-6 · Cited by 11
Thoracoscopic Left Atrial Appendage Excision Plus Ablation for Atrial Fibrillation to Prevent Stroke
Ni, B., Wang, Z., Gu, W., Li, M., Chen, M., Lip, G. Y. H., & Shao, Y. (2020) · Seminars in Thoracic and Cardiovascular Surgery · doi:10.1053/j.semtcvs.2020.06.041 · Cited by 11
Pharmacological and Non-pharmacological Treatments for Stroke Prevention in Patients with Atrial Fibrillation
Ueberham, L., Dagres, N., Potpara, T., Bollmann, A., & Hindricks, G. (2017) · Advances in Therapy · doi:10.1007/s12325-017-0616-6 · Cited by 11
Postoperative Atrial Fibrillation: Guidelines Revisited
Welker, C. C., & Ramakrishna, H. (2023) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2023.07.040 · Cited by 10
Left Atrial Appendage Occlusion: Current Stroke Prevention Strategies and a Shift Toward Data-Driven, Patient-Specific Approaches
Mendez, K. L., Kennedy, D. G., Wang, D. D., O'Neill, B. P., & Roche, E. T. (2022) · Journal of the Society for Cardiovascular Angiography & Interventions · doi:10.1016/j.jscai.2022.100405 · Cited by 10
Atrial Fibrillation in Heart Failure
Ellis, C. R., & Kanagasundram, A. N. (2019) · Cardiology Clinics · doi:10.1016/j.ccl.2019.01.009 · Cited by 9
Eurasian clinical guidelines for the diagnosis and treatment of atrial fibrillation in adult patients (2025)
Sp, G., Панченко, Е. П., Mironov, N. Y., Михайловна, Б. М., Gagloeva, D. A., Elfimova, E. M., Станиславовна, К. Е., Laiovich, L. I., Litvin, A. Y., Maykov, E. B., et al. (2025) · Eurasian heart journal · doi:10.38109/2225-1685-2025-3-6-77 · Cited by 8
2018 KHRS Guidelines for Stroke Prevention Therapy in Korean Patients with Nonvalvular Atrial Fibrillation
Lee, J., Joung, B., Cha, M., Lee, J. H., Lim, W., Kim, T., Shin, S. Y., Uhm, J., Lim, H. E., Kim, J., et al. (2018) · Korean Journal of Medicine · doi:10.3904/kjm.2018.93.2.87 · Cited by 8
A Comparative Study of Thoracoscopic Left Atrial Appendage Clipping vs Stapled Resection
Lim, S. K., Kim, C. H., Choi, K. H., Ahn, J., On, Y. K., Kim, S. M., & Jeong, D. S. (2023) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2023.09.010 · Cited by 8
2023 APHRS expert consensus statements on surgery for AF
Nitta, T., Wai, J. W. W., Lee, S. H., Yii, M. Y., Chaiyaroj, S., Ruaengsri, C., Ramanathan, T., Ishii, Y., Jeong, D. S., Chang, J., et al. (2023) · Journal of Arrhythmia · doi:10.1002/joa3.12939 · Cited by 8
Anesthetic Management of Patients Undergoing Percutaneous Endocardial and Epicardial Left Atrial Appendage Occlusion
Husain, Z., Safavi‐Naeini, P., Rasekh, A., Razavi, M., Collard, C. D., Anton, J. M., & Tolpin, D. A. (2017) · Seminars in Cardiothoracic and Vascular Anesthesia · doi:10.1177/1089253217714581 · Cited by 8
Left atrial appendage elimination techniques: stapled excision versus internal suture obliteration
Kang, Y., Hwang, H. Y., Joo, S., Park, J. H., Kim, J. S., Sohn, S. H., & Choi, J. W. (2021) · Journal of Thoracic Disease · doi:10.21037/jtd-21-1138 · Cited by 7
Exclusion versus preservation of the left atrial appendage in rheumatic mitral valve surgery
Kim, W. K., Kim, H. J., Kim, J. B., Jung, S. H., Choo, S. J., Chung, C. H., & Lee, J. W. (2020) · Heart · doi:10.1136/heartjnl-2019-316387 · Cited by 7
Why Follow-up Examinations After Left Atrial Appendage Closure Are Important: Detection of Complications During Follow-up and How to Deal with Them
Wunderlich, N. C., Lorch, G. C., Honold, J., Franke, J., & Küx, H. (2020) · Current Cardiology Reports · doi:10.1007/s11886-020-01357-3 · Cited by 6
A Novel Echocardiographic-Based Classification for the Prediction of Peri-Device Leakage following Left Atrial Appendage Occluder Implantation
Hamadanchi, A., Ijuin, S., Haertel, F., Bekfani, T., Westphal, J. G., Franz, M., Möbius‐Winkler, S., & Schulze, P. C. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11041059 · Cited by 6
Utilization of WATCHMAN FLX for surgically incomplete left atrial appendage occlusion: a multicentre case series
Golzarian, H., Mariam, A., Shah, S. R., Pasley, B. A., Ansah, K. N., Verma, A., Mehzad, R., & Patel, S. M. (2023) · European Heart Journal - Case Reports · doi:10.1093/ehjcr/ytad160 · Cited by 5
Percutaneous Left Atrial Appendage Occlusion Therapy: Evolution and Growing Evidence
Han, X.-Q., & Benditt, D. (2023) · Reviews in cardiovascular medicine · doi:10.31083/j.rcm2407211 · Cited by 5
Prevalence and Risk Factors of Incomplete Surgical Closure of the Left Atrial Appendage on Follow-up Transesophageal Echocardiogram
Lakkireddy, D. (2020) · Journal of Atrial Fibrillation · doi:10.4022/jafib.2357 · Cited by 5
Left Atrial Appendage Occlusion, A Misnomer?
Holmes, D. R., Simard, T., Killu, A. M., & Alkhouli, M. A. (2022) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2022.03.026 · Cited by 5
Left Atrial Appendage Occlusion Guided Only by Transesophageal Echocardiography
Zhao, J., Li, F., Zhang, Y., Zhuang, Z., Wang, M., Fu, L., Ni, Y., Lu, Z. X., Chen, Z., & Zhang, C. (2019) · Cardiology Research and Practice · doi:10.1155/2019/1376515 · Cited by 5
Clinical management after surgical left atrial appendage exclusion
Bhave, P. D., Dhaliwal, K. K., Chebrolu, S., Brock, J., Singleton, M. J., & Richardson, K. M. (2025) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-025-03378-x · Cited by 4
Current Endocardial Approaches for Left Atrial Appendage Closure
Rocca, D. G. D., Prete, A. D., Biase, L. D., Horton, R., Al‐Ahmad, A., Bassiouny, M., Mohanty, S., Trivedi, C. G., Romero, J. E., Gianni, C., et al. (2019) · European Journal of Arrhythmia & Electrophysiology · doi:10.17925/ejae.2019.5.1.40 · Cited by 4
Maze permutations during minimally invasive mitral valve surgery.
Lee, A. M. (2015) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2225-319x.2015.09.07 · Cited by 4
Long-Term Follow-Up of Left Atrial Appendage Exclusion: Results of the V-CLIP Multi-Center Post-Market Study
Zias, E. A., Phillips, K. G., Gerdisch, M., Johnson, S., El‐Eshmawi, A., Saum, K. A., Moront, M. G., Kasten, M. W., Singh, C., Bhatia, G., et al. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14155473 · Cited by 3
Left Atrial Appendage Management with the Watchman Device during Hybrid Ablation of Atrial Fibrillation
Vroomen, M., Maesen, B. A. E., LUERMANS, J. G. L. M., Crijns, H. J. G. M., Maessen, J. G., Meir, M. L., & Pison, L. (2019) · Journal of Interventional Cardiology · doi:10.1155/2019/4525084 · Cited by 3

Authors: Aryana, A., Singh, S. K., Singh, S. M., Gearoid O’Neill, P., Bowers, M. R., Allen, S. L., Lewandowski, S. L., Vierra, E. C., & d’Avila, A.
Affiliations: Dignity Health (US)
Sunnybrook Health Science Centre (CA)
Corresponding author: Aryana, Arash
ORCID: Aryana, Arash
Singh, Sheldon M.
Venue: Heart Rhythm
Publisher: Elsevier BV
Published: 2015-07
Volume: 12
Issue: 7
Pages: 1431-1437
ISSN: 1547-5271 (ISSN-L)
DOI: 10.1016/j.hrthm.2015.03.028
OpenAlex: W1602111967
Cited by: 184
References: 27
Citations by year: 2026: 22 · 2025: 16 · 2024: 7 · 2023: 17 · 2022: 15 · 2021: 21 · 2020: 23 · 2019: 18 · 2018: 16 · 2017: 21 · 2016: 7 · 2015: 1
FWCI: 10.88
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Heart Rhythm (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords: left atrial appendage, atrial fibrillation, ischemic stroke, systemic embolization, oral anticoagulation, atrial fibrillation recurrence, risk stratification, mitral valve surgery
MeSH terms: Aged, Aged, 80 and over, Atrial Fibrillation, Brazil, Female, Follow-Up Studies, Cardiac Surgical Procedures, Humans, Ligation, Male, Middle Aged, Postoperative Complications, Risk Factors, Thromboembolism, Echocardiography, Transesophageal, Risk Assessment, Atrial Appendage, Stroke, Wound Closure Techniques

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Association between incomplete surgical ligation of left atrial appendage and stroke and systemic embolization

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks