The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Severe cytomegalovirus encephalitis in an immunocompetent healthy young woman: A case report
Open accessAbstract
Cytomegalovirus (CMV) causes a mild illness in immunocompetent patients. Conversely, it can be life-threatening in immunocompromised or critically ill patients. We present a 48-year-old immunocompetent woman presenting primary severe CMV encephalitis. She presented with a headache, fever, and drowsiness. She did not respond to empirical treatment. Her level of consciousness deteriorated, she was put on mechanical ventilation on day two. Bacterial culture, herpes simplex virus, and tuberculosis were negative in cerebrospinal fluid (CSF). After three weeks, the patient was transferred to our center due to financial matters. Brain magnetic resonance imaging (MRI) showed diffuse hydrocephalus, periventricular T2 hyperintensity, patchy basal ganglia, and diffuse leptomeningeal enhancement. CMV polymerase chain reaction (PCR) was positive in cerebrospinal fluid (CSF) specimen. Ganciclovir (5 mg/kg/IV q12h) was initiated. Subsequently, a brain shunt was inserted. Her level of consciousness raised, she was weaned from the ventilator. She was discharged after 52 days in a bedridden state, quadriplegic, and only able to speak words with a minor swallowing problem. She remained in the same condition for one year. She was expired one year later due to aspiration pneumonia after four weeks of hospitalization. Early diagnosis and treatment of severe CMV encephalitis are crucial to prevent neurological sequelae.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“CMV meningoencephalitis is rare in immunocompetent adults but nevertheless appears to be more common than HHV-6 encephalitis in the same context [13].”
From Meningoencephalitis in a background of inherited chromosomic integration of HHV-6 and CMV infection in an immunocompetent adult, which one is the culprit? (2025) · cites this paper as [13]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cytomegalovirus disease in immunocompetent adults
Lancini, D. V., Faddy, H. M., Flower, R. L., & Hogan, C. (2014) · The Medical Journal of Australia · doi:10.5694/mja14.00183 · Cited by 122
Cytomegalovirus infection in immunocompetent critically ill adults: literature review
Al‐Omari, A., Aljamaan, F., Alhazzani, W. A., Salih, S., & Arabi, Y. M. (2016) · Annals of Intensive Care · doi:10.1186/s13613-016-0207-8 · Cited by 111
Li, X., Huang, Y., Xu, Z., Zhang, R., Liu, X., Li, Y., & Mao, P. (2018) · BMC Infectious Diseases · doi:10.1186/s12879-018-3195-5 · Cited by 103
Silva, J. D. M., Pinheiro-Silva, R., Dhyani, A., & Pontes, G. S. (2020) · BioMed Research International · doi:10.1155/2020/1627824 · Cited by 62
Cytomegalovirus pneumonia in immunocompetent host: Case report and literature review
Grilli, E., Galati, V., Bordi, L., et al. (2012) · Journal of Clinical Virology · doi:10.1016/j.jcv.2012.08.010 · Cited by 55
Prösch, S., Schielke, E., Reip, A., et al. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.12.3636-3640.1998 · Cited by 42
Handley, G. H., Pankow, S., Bard, J. D., Yee, R., Nigo, M., & Hasbun, R. (2021) · Journal of Clinical Virology · doi:10.1016/j.jcv.2021.104936 · Cited by 36
Baghban, A., & Malinis, M. F. (2018) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2018.02.029 · Cited by 27
CMV encephalitis in an immune-competent patient
Micallef, S., & Galea, R. (2018) · BMJ Case Reports · doi:10.1136/bcr-2018-224740 · Cited by 17
Encephalopathy Associated with Severe Cytomegalovirus Infection in an Immunocompetent Young Woman
Tetsuka, S., Suzuki, T., Ogawa, T., et al. (2021) · Case Reports in Infectious Diseases · doi:10.1155/2021/5589739 · Cited by 9
Xu, H., Chen, S., Lin, Q. F., Zhou, H., Huang, C., Lin, J., Xie, W., Chen, K., Zhou, D., Wan, M., et al. (2015) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s92366 · Cited by 8
Cytomegalovirus ileitis with protein-losing enteropathy in an immunocompetent adult
Ochiai, Y., Hoteya, S., Kono, K., et al. (2021) · Clinical Journal of Gastroenterology · doi:10.1007/s12328-021-01382-x · Cited by 7
CMV Encephalitis/Radiculitis: The Difficulty in Diagnosing in an Intubated Patient
Newcomb, G., Mariuz, P., & Lachant, D. J. (2019) · Case Reports in Critical Care · doi:10.1155/2019/8067648 · Cited by 6
Cited by
Lajoye, A.-L., Ciocanu, D., Duverlie, G., & Berquin, P. (2025) · IDCases · doi:10.1016/j.idcr.2025.e02219
“CMV meningoencephalitis is rare in immunocompetent adults but nevertheless appears to be more common than HHV-6 encephalitis in the same context [13].”
Metadata
- Authors
- Mozafarybazargany, M., & Khoshsirat, N. A.
- Affiliations
- Alborz University of Medical Sciences (IR)
- Corresponding author
- Khoshsirat, Nahid Abbasi
- Venue
- IDCases
- Publisher
- Elsevier BV
- Published
- 2022
- Volume
- 27
- Pages
- e01403
- ISSN
- 2214-2509 (ISSN-L)
- PMC
- PMC8763626
- OpenAlex
- W4205597782
- Cited by
- 12
- References
- 13
- Citations by year
- 2025: 6 · 2024: 4 · 2023: 1 · 2022: 1
- FWCI
- 2.17
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- IDCases (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Alborz University of Medical Sciences
- Topics
- Health Sciences › Medicine › Epidemiology › Cytomegalovirus and herpesvirus research
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Health Sciences › Medicine › Infectious Diseases › Herpesvirus Infections and Treatments
- Keywords
- cytomegalovirus encephalitis, primary CMV infection, immunocompetent patient, ganciclovir, cerebrospinal fluid PCR, hydrocephalus, neurological sequelae, tetraplegia, aspiration pneumonia, brain MRI findings
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
