Recent progress of collagen, chitosan, alginate and other hydrogels in skin repair and wound dressing applications
Abstract
Human understanding of skin is constantly ongoing. Great progress has been made in skin repair, wound dressing regeneration biomaterials research in recent years. This review introduced the clinical research and guiding principles of skin repair, wound dressing biomaterials at home and abroad, introduced the classification of various skin repair and wound dressing, listed the composition and performance of different dressing biomaterials, including traditional, natural, synthetic, tissue-engineered dressing materials were extensively reviewed. The biological molecular structures and biological function characteristics of different dressing biomaterials are comprehensively reviewed. Collagen, chitosan, alginate hydrogels et al. as the most popular biological macromolecules in skin repair and wound dressing applications were reviewed. The future development direction is also prospected. This paper reviews the research progress of advanced functional skin repair and wound dressing, which provides a reference for the modifications and applications of wound dressings.
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Blending chitosan with polymers such as collagen or alginate enhances its strength for barrier durability.
“Blending chitosan with polymers (e.g., collagen, alginate) enhances its strength for barrier durability [167].”
From Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering (2025) · cites this paper as [167]
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Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering
Fazel Anvari-Yazdi, A., Badea, I., & Chen, X. (2025) · Gels · doi:10.3390/gels11060441 · Cited by 20 · see citing works
- Authors
- Peng, W., Li, D., Dai, K., Wang, Y., Song, P., Li, H., Tang, P., Zhang, Z., Li, Z., Zhou, Y., & Zhou, C.
- Affiliations
- Sichuan University (CN)
- Corresponding author
- Dai, Kaili
- Zhou, Yuchi
- Venue
- International Journal of Biological Macromolecules
- Publisher
- Elsevier BV
- Published
- 2022-05
- Volume
- 208
- Pages
- 400-408
- ISSN
- 0141-8130 (ISSN-L)
- OpenAlex
- W4214932645
- Cited by
- 418
- References
- 0
- Citations by year
- 2026: 61 · 2025: 122 · 2024: 121 · 2023: 89 · 2022: 24 · 2021: 1
- FWCI
- 10.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- International Journal of Biological Macromolecules (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Biomaterials › Collagen: Extraction and Characterization
- Keywords
- collagen, chitosan, alginate, hydrogels, wound dressings, skin repair, biomaterials, natural polymers, synthetic polymers, wound healing
- MeSH terms
- Alginates, Bandages, Biocompatible Materials, Collagen, Humans, Skin, Wound Healing, Hydrogels, Chitosan
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