Biodegradable silk fibroin scaffold doped with mineralized collagen induces bone regeneration in rat cranial defects

Wei, Shuai; Wang, Yu; Sun, Yu; Gong, Leilei; Dai, Xiu; Meng, Haoye; Xu, Wenjing; Ma, Jianxiong; Hu, Qian; Ma, Xinlong; Peng, Jiang; Gu, Xiaosong

doi:10.1016/j.ijbiomac.2023.123861

Biodegradable silk fibroin scaffold doped with mineralized collagen induces bone regeneration in rat cranial defects

Compared with most nondegradable or slowly degradable bone repair materials, bioactive biodegradable porous scaffolds with certain mechanical strengths can promote the regeneration of both new bone and vasculature while the cavity created by their degradation can be replaced by the infiltration o…