Signal transduction and oncogenesis by ErbB/HER receptors

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Items 201–300 of 345

1. Strong dimerization of wild-type ErbB2/Neu transmembrane domain and the oncogenic Val664Glu mutant in mammalian plasma membranes
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2. The Relationship Among Neuregulin 1-Stimulated Phosphorylation of AKT, Psychosis Proneness, and Habituation of Arousal in Nonclinical Individuals
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3. MicroRNAs as the critical regulators of epithelial mesenchymal transition in pancreatic tumor cells
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4. COPI-Mediated Nuclear Translocation of EGFRvIII Promotes STAT3 Phosphorylation and PKM2 Nuclear Localization
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5. Effects of an EGFR-binding affibody molecule on intracellular signaling pathways.
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6. Investigation of HER-2 codon 655 single nucleotide polymorphism frequency and c-ErbB-2 protein expression alterations in gastric cancer patients.
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7. The ErbB Signaling Network and Its Potential Role in Endometrial Cancer
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8. Lapatinib Inhibits Amphiregulin-induced BeWo Choriocarcinoma Cell Proliferation by Reducing ERK1/2 and AKT Signaling Pathways
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9. Expression Levels and Significance of Nuclear Factor-κB and Epidermal Growth Factor Receptor in Hepatolithiasis Associated with Intrahepatic Cholangiocarcinoma
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10. The HER2-Binding Affibody Molecule (ZHER2∶342)2 Increases Radiosensitivity in SKBR-3 Cells
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11. The Effect of Hydrophilic Substitutions and Anionic Lipids Upon the Transverse Positioning of the Transmembrane Helix of the Erb b2 (neu) Protein Incorporated into Model Membrane Vesicles
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12. Expression of epidermal growth factor receptor in primary colorectal adenocarcinoma predicts expression in recurrent disease.
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13. Combination of Huanglian Jiedu Decoction and erlotinib delays growth and improves sensitivity of EGFR‑mutated NSCLC cells in vitro and in vivo via STAT3/Bcl‑2 signaling
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14. The use of protein array to identify targetable receptor tyrosine kinases for treatment of human colon cancer.
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15. Conversion of an MMP-potent scaffold to an MMP-selective HER-2 sheddase inhibitor via scaffold hybridization and subtle P1' permutations.
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16. Overexpression of EGFR in Oral Premalignant Lesions and OSCC and Its Impact on Survival and Recurrence
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17. Camel milk-derived exosomes as novel nanocarriers for curcumin delivery in lung cancer
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18. A Novel Mechanism Underlying the Inhibitory Effects of Trastuzumab on the Growth of HER2-Positive Breast Cancer Cells
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19. "Shedding" light on HER4 signaling in normal and malignant breast tissues.
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20. PlncRNA-1 induces apoptosis through the Her-2 pathway in prostate cancer cells
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21. The function of human epidermal growth factor receptor-3 and its role in tumors (Review).
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22. Multiparametric image analysis reveals role of Caveolin1 in endosomal progression rather than internalization of EGFR
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23. Monitoring the Size and Lateral Dynamics of ErbB1 Enriched Membrane Domains through Live Cell Plasmon Coupling Microscopy
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24. Optimizing the use of epidermal growth factor receptor inhibitors in advanced non-small-lung cancer (NSCLC).
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25. SCHOOL Model and New Targeting Strategies
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26. The Contorsbody, an antibody format for agonism: Design, structure, and function
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27. Abnormal Hypermethylation of CpG Dinucleotides in Promoter Regions of Matrix Metalloproteinases Genes in Breast Cancer and its Relation to Epigenomic Subtypes and HER2 Overexpression
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28. EGF Receptor Stalls upon Activation as Evidenced by Complementary Fluorescence Correlation Spectroscopy and Fluorescence Recovery after Photobleaching Measurements
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29. Pioglitazone inhibits EGFR/MDM2 signaling-mediated PPARγ degradation.
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30. Luteinizing Hormone–Induced Up-Regulation of ErbB-2 Is Insufficient Stimulant of Growth and Invasion in Ovarian Cancer Cells
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31. Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.
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32. Her-2/neu amplification and breast cancer survival: results from the Shanghai breast cancer study.
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33. Lysophosphatidic Acid, a Disintegrin and Metalloprotease-17 and Heparin-Binding Epidermal Growth Factor–Like Growth Factor in Ovarian Cancer: The First Word, Not the Last
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34. Wighteone exhibits an antitumor effect against EGFR L858R/T790M mutation non-small cell lung cancer
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35. Targeted next-generation sequencing of matched localized and metastatic primary high-risk SCCs identifies driver and co-occurring mutations and novel therapeutic targets.
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36. Natural Products as Chemopreventive Agents by Potential Inhibition of the Kinase Domain in ErbB Receptors
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37. Expression and Characterization of the Extracellular Domain of Human HER2 from Escherichia Coli, and Production of Polyclonal Antibodies Against the Recombinant Proteins
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38. Purification and characterization of recombinant extracellular domain of human HER2 from Escherichia coli.
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39. Therapeutic implications of signaling pathways and tumor microenvironment interactions in esophageal cancer
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40. EGFR/PPARδ/HSP90 pathway mediates cancer cell metabolism and chemoresistance
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41. Synergistic Growth Inhibition by Afatinib and Trametinib in Preclinical Oral Squamous Cell Carcinoma Models
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42. Downregulation of galectin-3 by EGF mediates the apoptosis of HepG2 cells
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43. Transmembrane Peptides from Tyrosine Kinase Receptor. Mutation-related Behavior in a Lipid Bilayer Investigated by Molecular Dynamics Simulations
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44. The mechanism of EGF in promoting skeletal muscle post-injury regeneration.
    Huai-Xin Teng, Yongze Liu, Ruotong Hao, Lu Zhang, Xiaoyu Zhang, Shu-Feng Li, Shuang Li, Hui-Li Tong · 2025 · Differentiation; research in biological diversity
45. Near-infrared targeted EGFR fluorescent probe for tumor imaging and diagnosis
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46. Heparin binding epidermal growth factor–like growth factor is a prognostic marker correlated with levels of macrophages infiltrated in lung adenocarcinoma
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47. Feminization of channel catfish with 17β-oestradiol involves methylation and expression of a specific set of genes independent of the sex determination region
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48. Endogenous thrombopoietin promotes non‐small‐cell lung carcinoma cell proliferation and migration by regulating EGFR signalling
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49. MicroRNA-18a induces epithelial-mesenchymal transition like cancer stem cell phenotype via regulating RKIP pathway in pancreatic cancer
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50. Phytoestrogens and mycoestrogens interacting with breast cancer proteins
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51. Dynamic Expression of MicroRNA-127 During Porcine Prenatal and Postnatal Skeletal Muscle Development
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52. Feasibility study of brain tumor delineation using immunolabeled gold nanorods.
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53. The SCHOOL of nature: III. From mechanistic understanding to novel therapies.
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54. A Peptide Antagonist of the ErbB1 Receptor Inhibits Receptor Activation, Tumor Cell Growth and Migration In Vitro and Xenograft Tumor Growth In Vivo
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55. The lipid second messenger diacylglycerol as a negative regulator of Rac signalling.
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56. Clinicopathological and prognostic values of ErbB receptor family amplification in primary osteosarcoma
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57. Synthesis and stability test of radiogadolinium(III)-DOTA-PAMAM G3.0-trastuzumab as SPECT-MRI molecular imaging agent for diagnosis of HER-2 positive breast cancer
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58. The Role of ErbB Receptors in Endometrial Cancer
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59. Novel irreversible EGFR tyrosine kinase inhibitor 324674 sensitizes human colon carcinoma HT29 and SW480 cells to apoptosis by blocking the EGFR pathway.
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60. The Val allele of HER-2 codon 655 predicts the progression of oral squamous cell carcinoma.
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61. HER2 Status Assessment in Endometrial Serous Carcinoma: Comparative Analysis of Two Proposed Testing and Interpretation Algorithms
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62. Diverse roles of epidermal growth factors receptors in oral and cutaneous canine melanomas
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63. Affibody‑mediated imaging of EGFR expression in prostate cancer using radiocobalt‑labeled DOTA‑ZEGFR:2377.
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64. Cetuximab in previously treated colorectal cancer.
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65. Purification and In Vitro Evaluation of an Anti-HER2 Affibody-Monomethyl Auristatin E Conjugate in HER2-Positive Cancer Cells
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66. Tumor‑penetrating peptide fused EGFR single‑domain antibody enhances radiation responses following EGFR inhibition in gastric cancer.
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67. Standard and Novel Therapies in Endometrial Cancer
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68. Effect of acute acid-base disturbances on ErbB1/2 tyrosine phosphorylation in rabbit renal proximal tubules
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69. Review Article: Targeted Therapy: Comprehensive Review
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70. Receptor Tyrosine Kinase (RTK) Mediated Tyrosine Phosphor-Proteome from Drosophila S2 (ErbB1) Cells Reveals Novel Signaling Networks
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71. SV40 T/t-common polypeptide specifically induces apoptosis in human cancer cells that overexpress HER2/neu.
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72. Design and identification of selective HER-2 sheddase inhibitors via P1' manipulation and unconventional P2' perturbations to induce a molecular metamorphosis.
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73. Structure-based virtual screening and molecular dynamics simulations for detecting novel candidates for allosteric inhibition of EGFRT790M
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74. ErbB Receptors and ErbB Targeted Therapies in Endometrial Cancer
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75. Mutual Regulation of Receptor-Mediated Cell Signalling and Endocytosis: EGF Receptor System as an Example
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76. Nonsurgical Treatment of Head and Neck Cancer
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77. TBB inhibits CK2/PD-L1/EGFR pathway-mediated tumor progression.
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78. Epidermal growth factor receptor-dependent stimulation of differentiation by human papillomavirus type 16 E5
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79. Molecular targeting in combination with platinum‐based chemoradiotherapy in head and neck cancer treatment
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80. Platelet Derived Growth Factor-B and Human Epidermal Growth Factor Receptor-2 Polymorphisms in Gall Bladder Cancer.
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81. EGF receptor dynamics in EGF-responding cells revealed by functional imaging during single particle tracking
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82. Synergistic anti-neoplastic effect of AG1478 in combination with cisplatin or paclitaxel on human endometrial and ovarian cancer cells.
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83. Incomplete surgical resection of ductal carcinomas in situ results in activation of ERBB2 in residual breast cancer cells.
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84. α-Mangostin Exhibits Antitumor Activity Against NCI-H1975 Cells via the EGFR/STAT3 Pathway: An Experimental and Molecular Simulation Study
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85. Obtaining and characterization of monoclonal antibodies against recombinant extracellular domain of human epidermal growth factor receptor 2
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86. Role of HER Family Members in Predicting Prognoses in Epithelial Ovarian Cancer: A Meta-analysis
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87. SV40 T/t-common polypeptide enhances the sensitivity of HER2-overexpressing human cancer cells to anticancer drugs cisplatin and doxorubicin.
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88. Epidermal Growth Factor‐Activated Extracellular Signal‐Regulated Kinase Suppresses Growth Hormone Expression and Stimulates Proliferation in MtT/ E Cells
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89. Screening and Validation of Dinucleotide Repeats in Intron 1 of the Human EGFR Gene and its Paralog in the HER2 Gene
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90. The era of ErbB-receptor-targeted therapies: advances toward personalized medicine.
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91. PPAR? Signaling: One Size Fits All?
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94. NSUN7 promotes cervical cancer progression through activation of ErbB signaling pathway
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95. ErbB4-encoded novel miRNAs act as tumor suppressors by regulating ErbB/PI3K signaling.
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96. EGFR nanovaccine in lung cancer treatment
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97. Molecular Mechanisms, Expression and Clinical Role of ErbB Receptors in Endometrial Cancer
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98. Sitting above the maze: recent model discoveries in molecular science
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99. Building Bridges toward Invasion: Tumor Promoter Treatment Induces a Novel Protein Kinase C-Dependent Phenotype in MCF10A Mammary Cell Acini
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100. Natural selection and functional diversification of the epidermal growth factor receptorEGFR family in vertebrates
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