Cutaneous endometriosis.
Open accessAbstract
Cutaneous endometriosis is a disorder that primarily affects women of reproductive age. The disorder is most commonly associated with cyclical pain during menses, but it can be difficult to diagnose in the absence of these symptoms and requires biopsy testing for a definitive diagnosis. We report on a case of a 41-year-old patient undergoing hormonal therapy for infertility who presented with a painful firm subcutaneous nodule in the umbilicus. She was ultimately diagnosed with cutaneous endometriosis and underwent surgical excision. In this report, we discuss the differential diagnosis and comment on treatment options, including surgical excision with wide margins or treatment with hormonal agents, such as danazol or leuprolide. Finally, we discuss whether patients with cutaneous endometriosis should receive an additional evaluation for pelvic endometriosis.
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Marras et al concluded in an 11-year retrospective study of endometriosis patients with involvement of the abdominal wall that symptoms are nonspecific.
“Marras et al23 concluded the same in an 11-year retrospective study of endometriosis patients with involvement of the abdominal wall, highlighting the nonspecific nature of symptoms in this disease.”
From Endometriosis in Patients Undergoing Plastic Surgical Procedures: A Case Report and Review of the Literature (2024) · cites this paper as [23]
The Introduction and Discussion (pages unavailable) say cutaneous endometriosis can mimic other conditions and be difficult to diagnose, supporting the general point about nonspecific presentation. Our copy does not mention Marras et al. or an 11-year retrospective study, so it does not support attributing that conclusion to such a study. (LLM, conf=0.82)
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References 6 · Cited by 43
- Authors
- Raffi, L., Suresh, R., McCalmont, T. H., & Twigg, A. R.
- Affiliations
- University of Southern California (US)
- University of California, San Francisco (US)
- Corresponding author
- Twigg, Amanda R.
- Venue
- International Journal of Women’s Dermatology
- Published
- 2019-12
- Volume
- 5
- Issue
- 5
- Pages
- 384-386
- ISSN
- 2352-6475 (ISSN-L)
- PMC
- PMC6938861
- OpenAlex
- W4240705232
- Cited by
- 43
- References
- 6
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 6 · 2023: 10 · 2022: 2 · 2021: 12 · 2020: 1 · 2017: 1 · 2016: 2 · 2013: 1
- FWCI
- 3.59
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Women’s Dermatology (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- eScholarship (California Digital Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Dermatology › Cancer and Skin Lesions
- Keywords
- cutaneous endometriosis, subcutaneous nodules, umbilicus, cyclical pain, infertility, hormone therapy, danazol, leuprolide, surgical excision, differential diagnosis, pelvic endometriosis
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